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Innovation Blues

Medical Information & Trusted Health Advice: Healthline - 0 views

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    Healthline is the first consumer medical search engine focused on delivering results from trusted, high-quality healthcare websites.
Innovation Blues

Caffeine: A User's Guide to Getting Optimally Wired - Developing Intelligence - 0 views

  • Caffeine: A User’s Guide to Getting Optimally Wired
  • Caffeine is the most widely used stimulant in the world, but few use it to maximal advantage. Get optimally wired with these tips.
  • 1) Consume in small, frequent amounts. Between 20-200mg per hour may be an optimal dose for cognitive function. Caffeine crosses the blood-brain barrier quickly (owing to its lipid solubility) although it can take up to 45 minutes for full ingestion through the gastro-intestinal tract. Under normal conditions, this remains stable for around 1 hour before gradually clearing in the following 3-4 hours (depending on a variety of factors). A landmark 2004 study showed that small hourly doses of caffeine (.3mg per kg of body weight [approx 20 mg per hour; thanks digg!]) can support extended wakefulness, potentially by counteracting the homeostatic sleep pressure, which builds slowly across the day and acts preferentially on the prefrontal cortex (an area of the brain thought responsible for executive and “higher” cognitive functions).
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  • 2) Play to your cognitive strengths while wired. Caffeine may increase the speed with which you work, may decrease attentional lapses, and may even benefit recall – but is less likely to benefit more complex cognitive functions, and may even hurt others. Plan accordingly (and preferably prior to consuming caffeine!)
  • Recall from memory may be improved by caffeine (here and here), possibly due to enhancements in memory encoding rather than retrieval per se. Another study shows caffeine can actually impair estimates of “memory scanning” speed (in the Sternberg paradigm), so the failure of many studies to find recall-related effects of caffeine may reflect a speed-accuracy tradeoff at the time of retrieval.
  • 3) Play to caffeine’s strengths. Caffeine’s effects can be maximized or minimized depending on what else is in your system at the time. The beneficial effects of caffeine may be most pronounced in conjunction with sugar. For example, one factor analytic study has shown caffeine-glucose cocktails provide benefits to cognition not seen with either alone.
  • Withdrawal symptoms can onset within 12 to 24 hours of caffeine consumption and last between 2 and 9 days.
  • some studies show grapefruit juice might keep caffeine levels in the bloodstream high for longer, though others have found no such effect
  • Similarly, nicotine may speed the metabolism of caffeine.
  • 4) Know when to stop – and when to start again. Although you may not grow strongly tolerant to caffeine, you can become dependent on it and suffer withdrawal symptoms. Balance these concerns with the cognitive and health benefits associated with caffeine consumption – and appropriately timed resumption.
  • Long-term ingestion of large quantities of caffeine (by way of coffee) is associated with a variety of health benefits – not only cognitive enhancements but also reduction in risk for type 2 diabetes (c.f.), Alzheimer’s and Parkinson’s . These beneficial effects may be related to the neuroprotective role of adenosine.
  • Caffeine’s effects might be masked by green tea extract, Kava Kava or St. John’s Wort – all of which contain theanine and are associated with subjective feelings of relaxation – but other preliminary evidence indicates the opposite effect: theanine might actually potentiate the benefits of caffeine on some tasks (reported in longer format here).
  • In addition, there are well-established cognitive effects where recall is best when it matches the context of encoding – so if you’re caffeinated when you study for the test, you better be caffeinated when you take it.
  • 5) Finding good sources of caffeine Despite the huge variety of sources of caffeine – including caffeinated soap, candy, and of course chocolate – the optimal use of caffeine is likely to involve small, hourly doses along with some cardioprotective agent. Given the high solubility of caffeine, absorption time should not be an issue (but if for some reason it is, try gum). Otherwise, why not enjoy a cup of green tea (coffee-flavored, if you must), as the Chinese have for nearly 5000 years? It’s hard to come by a better longitudinal study than that.
Innovation Blues

Comments on Economics: An ordinary Joe | The Economist - 0 views

  • Finally, countless Americans are, by world standards, vastly over-paid and have been found out. There is nothing a laborer in Manhattan can do that someone just as competent but living in El Salvador cannot do for perhaps one-fifth the price. It should be no surprise that 6% of the world's population can no longer enjoy 25% of the world's output -- there was no place to go but down.
  • Normally, the lack of a middle class would preclude a nation from being a world power, but the Anglo-American establishment was able to pay for American industrialization by borrowing British capital; from America’s inception until World War I, it was a debtor nation.
  • Unlike England, which prior to the welfare state of 1909, really did have a large middle class (roughly 40% of the population) America never did; for most of its history the middle class have never been more than 6% of Americans (probably less the 3% today). Middle Class values were the preserve of the WASP establishment, a small elite of German Jews, an even smaller elite of African-Americansand an assortment of assimilated white “ethnics”, but for the most part the American population was working class; focused on today, consuming all they produced.
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  • When Pat gets old he can retire comfortably and leave his widow comfortable as well, again was this because of savings, no; Pat got a company pension (inflation adjusted) and health care for the rest of his life with right of survivorship. All of this sounds great, but it wasn’t real; it was all a result of America ability to overcharge the world for capital goods; the costs of all these benefits were passed on to the rest of the world in higher priced capital good and dollar inflation. These programs allowed people to live middle class lives they never earned and could never keep (absent the programs). In fact, by 1970 it cost an American producer more in labor cost per ton of steel than what he could get for it on the world market. The fantasy world America has built post-World War 2 has been falling apart since the 1980s and the last leg, the dollars reserve currency status, is about to go. The disappearance of the American Dream is simply America reverting back to where its populations core values and behavior patterns would naturally take it.
  • The American Dream is rapidly fading because it was never real or at least never genuinely earned by Americans. When I speak of the “Middle Class”, I don’t simply mean possessing a middle class income, but rather having middle class patterns of behavior and world views. To be middle class is to be future time preference oriented; to accept short term pain for long term gain; to always be looking to get ahead and to plan ahead. Simply put, to be middle class is to consume less than what you produce, reinvesting the excess to produce more in the future.
  • America was the only large industrial power left standing after World War 2 and because it could charge the rest of the world what it wanted for capital goods, it could extract “rents” to support the fantasy of the American Dream. Consider the 1950s, the beginning of universal White middle-classdom and take a typical Irish guy; Pat. Pat grew up in an ethnic Irish slum like his father and grandfather, but he now can afford to buy a house; is it because he diligently saved his money and stayed focused, no; it is because he can get a VA loan or an FHA loan with no money down and easy payments. Pat dropped out of school at 16 and is not too interested in expanding his skills, is he on the streets, no; because of unions he can get an assembly line job. Moreover, because the NLR act effectively unionized every major industrial company and industry, Pat can look forward to annual raises (regardless of productivity) for his entire working life. When his children are old enough, Pat can afford to send them to college, is it because he saved before each child was born and spaced his children accordingly, no; they can get government loans , grants, and go to a subsides state college. When Pats parents get old they are not a burden, is it because they learned middleclass values and started to save, no; his parents rely on social security and Medicare (after 1965).
  • Europe is on the verge of a complete and total economic collapse...why?...because for decades their government has used force to take money from those who work hard and then give that money to those who don't work hard.
  • The capitalist equivalent of a socialist revolution is a Great Depression that wipes out the value of the paper assets the wealthy had accumulated, leaving the government to reallocate the real assets more equally. We almost had this happen in 2008, but the 1 percent blackmailed the rest with fear of collateral damage.
Innovation Blues

Joseph Stiglitz - Wikipedia, the free encyclopedia - 0 views

  • "They’ll say the IMF is arrogant. They’ll say the IMF doesn’t really listen to the developing countries it is supposed to help. They’ll say the IMF is secretive and insulated from democratic accountability. They’ll say the IMF's economic ‘remedies’ often make things worse – turning slowdowns into recessions and recessions into depressions. And they’ll have a point. I was chief economist at the World Bank from 1996 until last November, during the gravest global economic crisis in a half-century. I saw how the IMF, in tandem with the U.S. Treasury Department, responded. And I was appalled."
  • Initiative for Policy Dialogue In July 2000 Stiglitz founded the Initiative for Policy Dialogue (IPD), with support of the Ford, Rockefeller, McArthur, and Mott Foundations and the Canadian and Swedish governments, to enhance democratic processes for decision-making in developing countries and to ensure that a broader range of alternatives are on the table and more stakeholders are at the table.
  • Commission of Experts on Reforms of the International Monetary and Financial System Stiglitz at the World Economic Forum Annual Meeting in Davos, 2009. In 2009, Stiglitz chaired the Commission of Experts on Reforms of the International Monetary and Financial System which was convened by the President of the United Nations General Assembly "to review the workings of the global financial system, including major bodies such as the World Bank and the IMF, and to suggest steps to be taken by Member States to secure a more sustainable and just global economic order".[41] Its final report was released on 21 September 2009.[42][43]
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  • The Price of Inequality: How Today's Divided Society Endangers Our Future (2012) From the jacket: As those at the top continue to enjoy the best health care, education, and benefits of wealth, they often fail to realize that, as Joseph E. Stiglitz highlights, "their fate is bound up with how the other 99 percent live ... It does not have to be this way. In The Price of Inequality Stiglitz lays out a comprehensive agenda to create a more dynamic economy and fairer and more equal society"
Innovation Blues

Google's Self-Driving Cars: 300,000 Miles Logged, Not a Single Accident Under Computer ... - 0 views

  • "According to the World Health Organization, more than 1.2 million lives are lost every year in road traffic accidents. We believe our technology has the potential to cut that number, perhaps by as much as half."
  • he self-driving cars have now logged some 300,000 miles and "there hasn't been a single accident under computer control." (The New York Times did note in a 2010 article that a self-driving car was rear-ended while stopped at a traffic light, so Google must not be counting the incidents that were the fault of flawed humans.)
  • Google's cars would need to drive themselves (by themselves) more than 725,000 representative miles without incident for us to say with 99 percent confidence that they crash less frequently than conventional cars.
Innovation Blues

Carl Jung - Wikipedia, the free encyclopedia - 0 views

  • Individuation Jung considered individuation, a psychological process of integrating the opposites including the conscious with the unconscious while still maintaining their relative autonomy, necessary for a person to become whole.[2] Individuation is a process of transformation whereby the personal and collective unconscious is brought into consciousness (by means of dreams, active imagination or free association to take some examples) to be assimilated into the whole personality. It is a completely natural process necessary for the integration of the psyche to take place.[33] Individuation has a holistic healing effect on the person, both mentally and physically.[33] Besides achieving physical and mental health,[33] people who have advanced towards individuation tend to be harmonious, mature and responsible. They embody humane values such as freedom and justice and have a good understanding about the workings of human nature and the universe.[2]
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