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Innovation Blues

Caffeine: A User's Guide to Getting Optimally Wired - Developing Intelligence - 0 views

  • Caffeine: A User’s Guide to Getting Optimally Wired
  • Caffeine is the most widely used stimulant in the world, but few use it to maximal advantage. Get optimally wired with these tips.
  • 1) Consume in small, frequent amounts. Between 20-200mg per hour may be an optimal dose for cognitive function. Caffeine crosses the blood-brain barrier quickly (owing to its lipid solubility) although it can take up to 45 minutes for full ingestion through the gastro-intestinal tract. Under normal conditions, this remains stable for around 1 hour before gradually clearing in the following 3-4 hours (depending on a variety of factors). A landmark 2004 study showed that small hourly doses of caffeine (.3mg per kg of body weight [approx 20 mg per hour; thanks digg!]) can support extended wakefulness, potentially by counteracting the homeostatic sleep pressure, which builds slowly across the day and acts preferentially on the prefrontal cortex (an area of the brain thought responsible for executive and “higher” cognitive functions).
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  • 2) Play to your cognitive strengths while wired. Caffeine may increase the speed with which you work, may decrease attentional lapses, and may even benefit recall – but is less likely to benefit more complex cognitive functions, and may even hurt others. Plan accordingly (and preferably prior to consuming caffeine!)
  • Recall from memory may be improved by caffeine (here and here), possibly due to enhancements in memory encoding rather than retrieval per se. Another study shows caffeine can actually impair estimates of “memory scanning” speed (in the Sternberg paradigm), so the failure of many studies to find recall-related effects of caffeine may reflect a speed-accuracy tradeoff at the time of retrieval.
  • 3) Play to caffeine’s strengths. Caffeine’s effects can be maximized or minimized depending on what else is in your system at the time. The beneficial effects of caffeine may be most pronounced in conjunction with sugar. For example, one factor analytic study has shown caffeine-glucose cocktails provide benefits to cognition not seen with either alone.
  • Withdrawal symptoms can onset within 12 to 24 hours of caffeine consumption and last between 2 and 9 days.
  • Caffeine’s effects might be masked by green tea extract, Kava Kava or St. John’s Wort – all of which contain theanine and are associated with subjective feelings of relaxation – but other preliminary evidence indicates the opposite effect: theanine might actually potentiate the benefits of caffeine on some tasks (reported in longer format here).
  • Similarly, nicotine may speed the metabolism of caffeine.
  • 4) Know when to stop – and when to start again. Although you may not grow strongly tolerant to caffeine, you can become dependent on it and suffer withdrawal symptoms. Balance these concerns with the cognitive and health benefits associated with caffeine consumption – and appropriately timed resumption.
  • Long-term ingestion of large quantities of caffeine (by way of coffee) is associated with a variety of health benefits – not only cognitive enhancements but also reduction in risk for type 2 diabetes (c.f.), Alzheimer’s and Parkinson’s . These beneficial effects may be related to the neuroprotective role of adenosine.
  • some studies show grapefruit juice might keep caffeine levels in the bloodstream high for longer, though others have found no such effect
  • In addition, there are well-established cognitive effects where recall is best when it matches the context of encoding – so if you’re caffeinated when you study for the test, you better be caffeinated when you take it.
  • 5) Finding good sources of caffeine Despite the huge variety of sources of caffeine – including caffeinated soap, candy, and of course chocolate – the optimal use of caffeine is likely to involve small, hourly doses along with some cardioprotective agent. Given the high solubility of caffeine, absorption time should not be an issue (but if for some reason it is, try gum). Otherwise, why not enjoy a cup of green tea (coffee-flavored, if you must), as the Chinese have for nearly 5000 years? It’s hard to come by a better longitudinal study than that.
Innovation Blues

Nineteen Eighty-Four - Wikipedia, the free encyclopedia - 0 views

  • Nineteen Eighty-Four is a novel by George Orwell published in 1949. It is a dystopian and satirical novel set in Oceania, where society is tyrannized by The Party and its totalitarian ideology.[1] The Oceanian province of Airstrip One is a world of perpetual war, omnipresent government surveillance, and public mind control, dictated by a political system euphemistically named English Socialism (Ingsoc) under the control of a privileged Inner Party elite that persecutes all individualism and independent thinking as thoughtcrimes.[2] Their tyranny is headed by Big Brother, the quasi-divine Party leader who enjoys an intense cult of personality, but who may not even exist. Big Brother and the Party justify their rule in the name of a supposed greater good.[1]
  • George Orwell "encapsulate[d] the thesis at the heart of his unforgiving novel" in 1944, and three years later wrote most of it on the Scottish island of Jura, from 1947 to 1948, despite being seriously ill with tuberculosis.[4] On 4 December 1948, he sent the final manuscript to the publisher Secker and Warburg and Nineteen Eighty-Four was published on 8 June 1949.[5][6] By 1989, it had been translated into sixty-five languages, more than any other novel in English at the time.[7
  • Nineteen Eighty-Four is on Spacious Planet's list of "21 most surprising banned books" for having being banned in Russia and very nearly banned in the UK and the US.[29]
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  • The effect of Nineteen Eighty-Four on the English language is extensive; the concepts of Big Brother, Room 101, the Thought Police, thoughtcrime, unperson, memory hole (oblivion), doublethink (simultaneously holding and believing contradictory beliefs) and Newspeak (ideological language) have become common phrases for denoting totalitarian authority. Doublespeak and groupthink are both deliberate elaborations of doublethink, while the adjective "Orwellian" denotes "characteristic and reminiscent of George Orwell's writings" especially Nineteen Eighty-Four.
  • In September 2009, an album entitled The Resistance was released by English Alternative rock band Muse, which was based entirely on 1984[citation needed], including songs such as "Resistance", "Uprising" and "United States of Eurasia". The album resulted in Muse receiving a Grammy for Best Rock Album at the 53rd Grammys.
  • In November 2011, the United States government argued before the U.S. Supreme Court that it wants to continue utilizing GPS tracking of individuals without first seeking a warrant. In response, Justice Stephen Breyer questioned what this means for a democratic society by referencing Nineteen Eighty-Four. Justice Breyer asked, "If you win this case, then there is nothing to prevent the police or the government from monitoring 24 hours a day the public movement of every citizen of the United States. So if you win, you suddenly produce what sounds like 1984...."[65] In 1984, the book was made into a movie. In 2006, the movie V for Vendetta was released, which has many of the same running themes and principles.[66][67] In Nineteen Eighty-Four, John Hurt portrays Winston Smith, while in V for Vendetta he plays the Big Brother-like figure.[68][69]
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