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Nathan Goodyear

The HK2 Dependent "Warburg Effect" and Mitochondrial Oxidative Phosphorylation in Cancer: Targets for Effective Therapy with 3-Bromopyruvate - 0 views

www.ncbi.nlm.nih.gov/...PMC6273842

cancer hexokinase "hexokinase 2" 3BP LDH 3-bromopyruvate "pyruvate dehydrogenase" "pyruvate dehydrogenase kinase" "lactate

shared by Nathan Goodyear on 20 Jan 19 - No Cached
  • Nathan Goodyear on 20 Jan 19
     
    biochemistry strikes again: hexokinase 2 shown to be key step in cancer proliferation, energy metabolism and mortality. 3BP shown to be a potent glycolytic inhibitor and in animal studies shown to have significant mortality effects on cancer. Also, great review of cancer cell metabolism i.e Warburg effect, Crabtree effect, LDH, PD, PDK...
Nathan Goodyear

3-Bromopyruvate (3BP) a fast acting, pro... [J Bioenerg Biomembr. 2012] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...22382780

cancer 3-bromopyruvate 3-BrPA

shared by Nathan Goodyear on 11 Sep 13 - No Cached
  • Nathan Goodyear on 11 Sep 13
     
    Just the abstract of this article is available.  3-Bromopyruvate useful in cancer treatments to stunt cancer ATP production.
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