CoQ10 can significantly extend survival, delay motor deficits and delay weight loss and attenuate the development of striatal atrophy in a transgenic mouse model of HD
Pilot study and only abstract available here: Low CoQ10 levels found in amniotic sample in preterm delivered pregnancies; not difference was found in serum levels.
low CoQ10 associated with spontaneous miscarriage in abstract. The authors of this paper found CoQ10 levels increased throughout "normal pregnancy". Only abstract available here.
CoQ10 supplementation of 150 mg in individuals with CAD found to have increased catalase activity, increased SOD activity, an increased MDA levels. This reduced oxidative stress, TC, and LDL levels.
high dose CoQ10 shown to slow disease progression in Parkinson's disease. A similar study had shown the same finding in Huntington's disease. Both are excitotoxic diseases
CoQ10 reduced inflammatory cytokines IL-6 and TNF-alpha. CoQ10 also increased SOD, catalase, and glutathione perioxidase. The duration of therapy was quite short--12 weeks. The patients included in the study had pre-existing CAD.
study finds prolonged exposure to estrogen associated with increased colorectal cancer risk in postmenopausal women. So many unanswered questions. What was the ER status of these patients? What was the weight of these patients? One cannot simply compare estrogen exposure to colorectal cancer risk and say aha! What is the environment of the individual(s)?!Thanks
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