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Nathan Goodyear

Testosterone physiology in resistance exercise an... [Sports Med. 2010] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...21058750

resistance exercise physiology testosterone men male hormone hormones

shared by Nathan Goodyear on 29 Jul 14 - No Cached
  • testosterone stimulates protein synthesis
  • promotion of muscle hypertrophy by testosterone
  • intracellular androgen receptor (AR)
  • ...8 more annotations...
  • In general, testosterone concentration is elevated directly following heavy resistance exercise in men
  • Findings on the testosterone response in women are equivocal with both increases and no changes observed in response to a bout of heavy resistance exercise
  • Age also significantly affects circulating testosterone concentrations.
  • Aging beyond 35-40 years is associated with a 1-3% decline per year in circulating testosterone concentration in men
  • aging results in a reduced acute testosterone response to resistance exercise in men.
  • In women, circulating testosterone concentration also gradually declines until menopause, after which a drastic reduction is found.
  • acute increases in testosterone can be induced by resistance exercise
  • testosterone is an important modulator of muscle mass in both men and women
  • Nathan Goodyear on 29 Jul 14
     
    Resistance training to increase endogenous Testosterone production: more specific, the exercise must be high rep or as the authors call it--high volume.  To do this, the weight needs to be light.
Nathan Goodyear

Characteristics of Secondary, Primary, and Compensated Hypogonadism in Aging Men: Evide... - 0 views

press.endocrine.org/...jc.2009-1796

low T low Testosterone hypogonadism aging obesity men male hormone hormones

shared by Nathan Goodyear on 30 Mar 15 - No Cached
  • Circulating testosterone (T) in men declines progressively by 0.4–2% per year from the third decade onward
  • late-onset hypogonadism (LOH) (6, 7), whereas others have used various terms including andropause, male menopause, and androgen deficiency syndrome of the aging male.
    • Nathan Goodyear
      Nathan Goodyear on 30 Mar 15
       
      all names for Low T--interesting
  • Secondary hypogonadism is associated with obesity (and potentially reversible) independently of age
  • ...2 more annotations...
  • primary hypogonadism (probably the genuine form of LOH) is strongly associated with age
  • Compensated hypogonadism represents a distinct clinical entity that warrants continued monitoring to prevent or preempt further deterioration
  • Nathan Goodyear on 30 Mar 15
     
    Study divides low T into primary (age), secondary (weight), and compensated hypogonadism (elevated LH with normal T)
Nathan Goodyear

Sex hormones affect neurotransmitters and shape the adult female brain during hormonal ... - 0 views

www.ncbi.nlm.nih.gov/...PMC4335177

hormones neurotransmitters serotonin GABA dopamine estradiol progesterone glutamate

shared by Nathan Goodyear on 11 Jul 17 - No Cached
  • estrogen administration has been found to increase tryptophan hydroxylase
  • 5-HT2A mRNA levels in brain areas relevant for the control of mood, mental state and cognition (Sumner and Fink, 1998) and 5-HTT mRNA when administered for a longer period
  • n the other hand, estrogen treatment has also been observed to decrease mRNA related to serotonergic neurotransmission
  • ...4 more annotations...
  • Furthermore, acute estrogen administration decreases 5-HTT mRNA levels (Pecins-Thompson et al., 1998) and 5-HT1A mRNA levels and binding
  • assigning the effects of estrogen on serotonin to a homogenous functional class of stimulation or inhibition seems not to be feasible
  • Progesterone has been suggested to increase serotonergic neurotransmission via the regulation of the expression of serotonin-related genes and proteins
  • menopausal women gain less benefit from antidepressant treatments compared to women during their reproductive years
  • Nathan Goodyear on 11 Jul 17
     
    good review of the relationship of the sex hormones and neurotransmitters.
Nathan Goodyear

Subcutaneous testosterone-letrozole therapy before and concu... : Menopause - 0 views

journals.lww.com/...trozole_therapy_before.21.aspx

breast cancer Testosterone aromatase inhibitor Estradiol lotrazole

shared by Nathan Goodyear on 15 Jul 19 - No Cached
  • Nathan Goodyear on 15 Jul 19
     
    Testosterone SQ pellets + AI letrozole associated with a reduction in breast cancer survival.
Nathan Goodyear

Type and timing of menopausal hormone therapy and breast cancer risk: individual partic... - 2 views

www.thelancet.com/...fulltext

cancer hormones

shared by Nathan Goodyear on 06 Sep 19 - No Cached
  • Nathan Goodyear on 06 Sep 19
     
    To be read
Nathan Goodyear

Hormone Replacement Therapy Associated with Lower Mortality - American College of Cardi... - 0 views

www.acc.org/...ssociated-with-lower-mortality

HRT hormone replacement therapy hormones menopause atherosclerosis cardiovascular disease hormone therapy

shared by Nathan Goodyear on 22 Mar 17 - No Cached
  • Nathan Goodyear on 22 Mar 17
     
    Just a press release of yet to be published study that finds women on HRT have lower atherosclerosis, calcium score, and death than younger women not on HRT.
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