Skip to main content

Home/ Dr. Goodyear/ Group items tagged marks

Rss Feed Group items tagged

Filter: All | Bookmarks | Topics Simple Middle
1More

Get rid of the Stretch Marks | Best Stretch Marks Removal Laser Treatment - Pixigenus -... - 1 views

youtu.be/W7nUffxg5Rk hormones hormone cancer Testosterone inflammation Men disease Male obesity low
shared by kunalkumar03 on 01 Feb 19 - No Cached
  • kunalkumar03 on 01 Feb 19
     
    Stretch marks are formed deep within the dermis layer and happen due to rapid stretching, this causes damage to the skin's connecting tissues. To get rid of these stretch marks we are introducing to you our latest laser treatment i.e. PIXIGENUS. It is a unique technology to eliminate stretchmarks from various parts of the body. Watch the full video to know more. Stretch marks are caused because of rapid stretching of the skin that results into scars and discoloration of the skin. There are many reasons which can lead to stretch marks such as rapid weight reduction, quick weight gain, excessive exercise, steroids, pregnancy, hormonal changes, puberty etc. Millions of women have stretch marks, but this fact does little to lessen the embarrassment that most women feel at the appearance of these unattractive striations on their skin. Stretch marks, also known as striae, are a form of scarring on the skin with an off-color hue. Over time they may reduce, but will not disappear completely. Tearing of the dermis results into stretch marks.

Prevention Cream For Stretch Marks - 1 views

started by Stretch Marks on 28 Feb 12 no follow-up yet

Prevention Cream For Stretch Marks - 1 views

started by Stretch Marks on 29 Feb 12 no follow-up yet

My Effective Stretch Mark Cream - 3 views

started by stretchmark treatment on 23 Mar 12 no follow-up yet

Effective Stretch Mark Remedy - 4 views

started by Justin Stone on 28 Feb 12 no follow-up yet

Effective Stretch Mark Remedy - 1 views

started by Justin Stone on 29 Feb 12 no follow-up yet

Effective Stretch Mark Remedy - 3 views

started by Justin Stone on 07 Mar 12 no follow-up yet
1More

Stretch Marks Removal Abu Dhbai and Sharjah - 0 views

www.laserskincaretreatments.ae/...stretch-marks-removal #stretchmarksremovalAbuDhbai #StretchmarkstreatmentAbuDhabi #stretchmarksSharjah #StretchmarksremovalSharjah #Stretchmarks
shared by hadiyasafdar on 30 Jan 17 - No Cached
  • hadiyasafdar on 30 Jan 17
     
    Stretch marks are a very common skin issue that is faced by many women. They are grayish white linear marks that appear on the skin surface to excessive skin stretching
1More

The Role of Nutraceutical Supplements in the Treatment of Dyslipidemia - Houston - 2012... - 0 views

onlinelibrary.wiley.com/...full Mark Houston dyslipidemia neutraceuticals CVD cardiovascular disease HTN supplements vitamins
shared by Nathan Goodyear on 27 Sep 12 - No Cached
  • Nathan Goodyear on 27 Sep 12
     
    Dr. Mark Houston discusses the use of neutraceuticals to treat dyslipidemia and CVD.
41More

Lowered testosterone in male obesity: Mechanisms, morbidity and management Tang Fui MN,... - 0 views

www.ajandrology.com/article.asp Testosterone male obesity overweight men hormone hormones low T Low T
shared by Nathan Goodyear on 15 Jan 14 - No Cached
  • The number of overweight people is expected to increase from 937 million in 2005 to 1.35 billion in 2030
  • Similarly the number of obese people is projected to increase from 396 million in 2005 to 573 million in 2030
  • By 2030, China alone is predicted to have more overweight men and women than the traditional market economies combined
  • ...37 more annotations...
  • diacylglycerol O-acyltransferase 2 (DGAT2), mechanistically implicated in this differential storage, [10] is regulated by dihydrotestosterone, [11] suggesting a potential role for androgens to influence the genetic predisposition to either the MHO or MONW phenotype.
  • bariatric surgery achieves 10%-30% long-term weight loss in controlled studies
  • The fact that obese men have lower testosterone compared to lean men has been recognized for more than 30 years
  • Reductions in testosterone levels correlate with the severity of obesity and men
  • epidemiological data suggest that the single most powerful predictor of low testosterone is obesity, and that obesity is a major contributor of the age-associated decline in testosterone levels.
  • healthy ageing by itself is uncommonly associated with marked reductions in testosterone levels
  • obesity blunts this LH rise, obesity leads to hypothalamic-pituitary suppression irrespective of age which cannot be compensated for by physiological mechanisms
  • Reductions in total testosterone levels are largely a consequence of reductions in sex hormone binding globulin (SHBG) due to obesity-associated hyperinsulinemia
  • although controversial, measurement of free testosterone levels may provide a more accurate assessment of androgen status than the (usually preferred) measurement of total testosterone in situations where SHBG levels are outside the reference range
  • SHBG increases with age
  • marked obesity however is associated with an unequivocal reduction of free testosterone levels, where LH and follicle stimulating hormone (FSH) levels are usually low or inappropriately normal, suggesting that the dominant suppression occurs at the hypothalamic-pituitary level
  • adipose tissue, especially when in the inflamed, insulin-resistant state, expresses aromatase which converts testosterone to estradiol (E 2 ). Adipose E 2 in turn may feedback negatively to decrease pituitary gonadotropin secretion
  • diabetic obesity is associated with decreases in circulatory E 2
  • In addition to E 2 , increased visceral fat also releases increased amounts of pro-inflammatory cytokines, insulin and leptin; all of which may inhibit the activity of the HPT axis at multiple levels
  • In the prospective Massachusetts Male Aging Study (MMAS), moving from a non-obese to an obese state resulted in a decline of testosterone levels
  • weight loss, whether by diet or surgery, increases testosterone levels proportional to the amount of weight lost
  • fat is androgen-responsive
  • low testosterone may augment the effects of a hypercaloric diet
  • In human male ex vivo adipose tissue, testosterone decreased adipocyte differentiation by 50%.
  • Testosterone enhances catecholamine-induced lipolysis in vitro and reduces lipoprotein lipase activity and triglyceride uptake in human abdominal adipose tissue in vivo
  • in men with prostate cancer receiving 12 months of androgen deprivation therapy, fat mass increased by 3.4 kg and abdominal VAT by 22%, with the majority of these changes established within 6 months
  • severe sex steroid deficiency can increase fat mass rapidly
  • bidirectional relationship between testosterone and obesity
  • increasing body fat suppresses the HPT axis by multiple mechanisms [30] via increased secretion of pro-inflammatory cytokines, insulin resistance and diabetes; [19],[44] while on the other hand low testosterone promotes further accumulation of total and visceral fat mass, thereby exacerbating the gonadotropin inhibition
  • androgens may play a more significant role in VAT than SAT
  • men undergoing androgen depletion for prostate cancer show more marked increases in visceral compared to subcutaneous fat following treatment
    • Nathan Goodyear
      Nathan Goodyear on 16 Jan 14
       
      Interesting: low T increases VAT, yet T therapy does not reduce VAT, yet T therapy reduces SAT.
  • irisin, derived from muscle, induces brown fat-like properties in rodent white fat
  • androgens can act via the PPARg-pathway [37] which is implicated in the differentiation of precursor fat cells to the energy-consuming phenotype
  • low testosterone may compound the effect of increasing fat mass by making it more difficult for obese men to lose weight via exercise
  • pro-inflammatory cytokines released by adipose tissue may contribute to loss of muscle mass and function, leading to inactivity and further weight gain in a vicious cycle
  • Sarcopenic obesity, a phenotype recapitulated in men receiving ADT for prostate cancer, [55] may not only be associated with functional limitations, but also aggravate the metabolic risks of obesity;
  • observational evidence associating higher endogenous testosterone with reduced loss of muscle mass and crude measures of muscle function in men losing weight
  • genuine reactivation of the HPT axis in obese men requires more substantial weight-loss
  • A number of intervention studies have confirmed that both diet- and surgically-induced weight losses are associated with increased testosterone, with the rise in testosterone generally proportional to the amount of weight lost
  • men, regardless of obesity level, can benefit from the effect of weight loss.
  • inconsistent effect of testosterone on VAT
  • Nathan Goodyear on 15 Jan 14
     
    to be read
1More

The Beneficial Effects of Antioxidant Supplementation in Enteral Feeding in Critically ... - 0 views

www.anesthesia-analgesia.org/...857.long IV intravenous vitamin C E critically ill sepsis antioxidant therapy treatment
shared by Nathan Goodyear on 29 Feb 12 - No Cached
  • Nathan Goodyear on 29 Feb 12
     
    IV vitamin C and vitamin E was found to lower the mortality rate in those with critical illness at the 28 day mark.  This study showed the safety and efficacy of IV vitamin C and vitamin E in those critically ill.
1More

Curcumin inhibits proliferation of breast cancer cells through Nrf2-mediated down-regul... - 0 views

www.sciencedirect.com/...S096007601400020X breast cancer curcumin natural alternative Nrf2
shared by Nathan Goodyear on 24 Jun 14 - No Cached
  • Nathan Goodyear on 24 Jun 14
     
    Another mark for cucumin in the battle against cancer.  This article looked at the mechanism behind the inhibition of cell proliferation by curcumin.  The proposed mechanism is via Nrf2 induction in the MCF-7 cell culture lines.
1More

Scopus - Document details - 0 views

www.scopus.com/...display.url amino acids high protein diet insulin resistance
shared by Nathan Goodyear on 21 Oct 13 - No Cached
  • Nathan Goodyear on 21 Oct 13
     
    Amino acids contribute to skeletal muscle insulin resistance.  A marked glycogen synthesis decrease (64%) was found in this study.
2More

Reversal of Maternal Programming of Stress Responses in Adult Offspring through Methyl ... - 0 views

www.jneurosci.org/...11045.full epigenetics stress
shared by Nathan Goodyear on 18 Mar 11 - No Cached
  • These results demonstrate that, despite the inherent stability of the epigenomic marks established early in life through behavioral programming, they are potentially reversible in the adult brain.
  • Nathan Goodyear on 18 Mar 11
     
    We are products of our genetics and our environment
1More

Effects of Transdermal Testosterone Treatment o... [Endocr Pract. 2014] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...25100359 Testosterone inflammation men male hormone hormones therapy treatment
shared by Nathan Goodyear on 13 Aug 14 - No Cached
  • Nathan Goodyear on 13 Aug 14
     
    No decrease or trend for lower inflammatory markers seen in Testosterone therapy in men > 65.  These men had levels of T < 475 ng/dl, which brings into question this studies results as most studies point to 300 or 250 as the mark.
24More

Oxidative Stress and Its Relationship With Adenosine Deaminase Activity in Various Stag... - 0 views

www.ncbi.nlm.nih.gov/...PMC3547448 Adenosine Deaminase ADA cancer breast cancer superoxide disumutase glutathione peroxidase oxidative stress inflammation
shared by Nathan Goodyear on 10 Nov 14 - No Cached
  • Reduced SOD activity might be responsible for excessive accumulation of superoxide anions leading to increased free radical mediated injury. Increased free radical production has been shown to be responsible for chromosomal damage leading to mutagenecity, cell proliferation and carcinogenesis. SOD activity showed marked improvement after mastectomy indicating the lowering of oxidative stress.
  • The increased production of reactive oxygen species causes oxidative stress leading to cell proliferation and hence increased inflammatory conditions
  • Superoxide dismutase is an important antioxidant enzyme which decomposes the harmful superoxide anions into hydrogen peroxide thus protects the body from the action of free radicals
  • ...20 more annotations...
  • Females suffering from breast cancer had significantly decreased Superoxide dismutase (SOD) and reduced glutathione (GSH) levels in comparison to normal females
  • ADA seems to be a promising marker of inflammation in breast cancer thereby suggesting that it can be used as a diagnostic tool to detect the stage of breast cancer along with cytopathological studies
  • In conclusion, our study confirmed the role of oxidative stress in the pathogenesis of breast cancer.
  • Another potent antioxidant molecule is reduced glutathione. It acts as reductant which converts hydrogen peroxide into water and reduces lipid peroxidation products into their corresponding alcohols and thus mediates protective action.
  • In the present study, significantly low SOD activity has been observed in female patients suffering from carcinoma breast both pre as well as post operative in comparison to healthy females.
  • We observed significantly decreased SOD activity and GSH levels in patients belonging to clinical stage 4 as compared to those having stages 1, 2 or 3 of breast cancer.
  • Increased ADA activity in breast cancer patients has also been reported
  • The compromised antioxidant defence system produces the oxidative stress which in turn creates the inflammatory response shown by concomitant increased adenosine deaminase (ADA) activity in female patients.
  • Experimental and epidemiological evidences implicate the involvement of oxygen derived free radical in the pathogenesis of breast cancer.
  • Antioxidant status was highly depressed in advanced stages of breast cancer as compared to initial stage.
  • In the present study, significantly low GSH levels were observed in female patients of carcinoma breast as compared to normal females
  • Walia et al. (1995) reported increased ADA activity in breast cancer patients as compared to age matched normal subjects.
  • These free radicals are able to cause damage to membrane, mitochondria and macromolecules including proteins, lipids and DNA and actively take part in cell proliferation. This cascade in turn generates the inflammatory response and causes the progression of the disease.
  • increased oxidative stress gives rise to inflammation which could further aggravates the disease
  • Breast carcinoma involves a cascade of events that are highly inflammatory.
  • Marked oxidative stress in stage 4 of breast cancer indicated advancement of the disease, hence checking oxidative stress at initial stage could be helpful for controlling the progression of the disease.
  • They concluded that ADA is a better probable parameter for detection of breast cancer
  • Adenosine deaminase enzyme (ADA) catalyzes the conversion of adenosine to inosine which finally gets converted to uric acid
  • serum ADA activity tends to increase with advancing age,
  • Prevalence of oxidative stress gives rise to inflammation.
  • Nathan Goodyear on 10 Nov 14
     
    Study finds a reduction in SuperOxide Dismutase and Glutathione Perioxidase in advancing breast cancer.  Cancer is a high oxidative stress disease that results in inflammation, mitochondrial dysfunction and proliferation.  Adenosine Deaminase (ADA) is proposed to be another biomarker to assess tumor stage.  
1More

Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection ... - 0 views

www.ncbi.nlm.nih.gov/...PMC8095229 COVID COVID19 COVID-19
shared by Nathan Goodyear on 27 Jul 21 - No Cached
  • Nathan Goodyear on 27 Jul 21
     
    Only natural immunity through infection provides the most durable B and T cells for long-term immunity. Vaccinations miss the mark.
1More

Curcumin interrupts the interaction between the androgen receptor and Wnt/β-c... - 0 views

www.nature.com/...pcan201026 curcumin PSA AR prostate cancer WNT Beta-catenin androgen receptor
shared by Nathan Goodyear on 22 Sep 20 - No Cached
  • Nathan Goodyear on 22 Sep 20
     
    Curcumin was shown to induce significant inhibition of AR expression in a dose-dependent manner. Marked curcumin-induced suppression of β-catenin
1More

New Technique by Low Cost Top 10 Heart Valve Surgeons in India Safer for Some High-Risk... - 0 views

www.briefingwire.com/...er-for-some-high-risk-patients low-cost top 10 heart valve surgeons in India top 10 heart valve surgeons in India heart valve surgeons Heart Valve Replacement in India lowest price for heart valve replacement surgery in India Heart valve replacement surgeons in India
shared by indiacardiacsurg on 28 Oct 21 - No Cached
  • indiacardiacsurg on 28 Oct 21
     
    "All patients had a successful TAVR without a coronary obstruction, stroke, or any major worry," stated low-cost top 10 heart valve surgeons in India. "They have been doing very well as they reached the 30-day-mark after undergoing the procedure." For Consultation International Helpline Number : +91-9370586696 Email id: enquiry@indiacardiacsurgerysite.com
1 - 20 of 46 Next › Last »
Showing 20▼ items per page