Effect of aging on endogenous level of 5 alpha-dihydrotestosterone, testosterone, estra... - 0 views
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Nathan Goodyear on 18 Sep 12Men with BPH found to have higher levels of stromal Estradiol and Estrone. This is associated with aging. This elevation was not found in the prostate epithelium. No correlation with Testosterone and the stroma and epithelium were found. So, the point is that what is happening in the prostate appears to be related to increased aromatase activity in the prostate. Which this has been shown to be evident in the lateral lobes of the prostate in other studies. But DHT? The numbers here are slightly elevated. BUt the balance of DHT to Estradiol may be more important than the individual levels. This study was done in humans.