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Nathan Goodyear

Hypothalamic-pituitary-adrenal stress axis function and the relationship with chronic w... - 0 views

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    Those with chronic pain shown to have HPA dysfunction.  Elevated cortisol was found via saliva evaluation.  This with pain had the higher cortisol levels.
Nathan Goodyear

Salivary cortisol as a diagnostic tool for ... [Eur J Endocrinol. 2012] - PubMed - NCBI - 0 views

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    European Journal of Endocrinology finds that salivary cortisol can be used as a diagnostic tool for Cushing's syndrome and adrenal insufficiency.  Thus both hypercortisol and hypocortisol states can be followed using saliva.  This statement was using immunoassay.  Mass spectroscopy provides even better results
Nathan Goodyear

Stress-induced hypocortisolemia diagnosed a... [Ann N Y Acad Sci. 2005] - PubMed - NCBI - 0 views

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    Always remember to evaluate cortisol in post stress psychiatric disorders.  normallzation of cortisol can resolve psychiatric condition indicating that the underlying etiology is adrenal in nature.
Nathan Goodyear

Cambridge Journals Online - Proceedings of the Nutrition Society - Fulltext -... - 0 views

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    Peripheral 11Beta-HSD1 plays critical role in fat metabolism and energy utilization.  Good discussion on the role that extra-adrenal 11Beta-HSD1 plays in metabolism
Nathan Goodyear

[Salivary cortisol in adrenal diseases] [Tidsskr Nor Laegeforen. 2007] - PubMed result - 0 views

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    Salivary cortisol in adrenal diseases
Nathan Goodyear

Concentrations of total and free dehydroepiandrosterone in plasma and dehydroepiandrost... - 0 views

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    Conclusion: "the concentration of DHEA in saliva is a reliable index of adrenal DHEA secretion..."
Nathan Goodyear

Cortisol awakening response and nighttime salivary... [Yonsei Med J. 2011] - PubMed result - 0 views

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    salivary cortisol useful in evaluating hypothalamus-pituitary-adrenal axis system
Nathan Goodyear

Immunohistochemical localization of ... [J Clin Endocrinol Metab. 1998] - PubMed - NCBI - 0 views

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    11beta-HSD type I is highly expressed in liver, adrenal glands, ovaries, and adipose tissue in human immunohistochemical analysis.
Nathan Goodyear

Pituitary-adrenocortical function in abdominal obesity of males: ev... - PubMed - NCBI - 0 views

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    Obesity associated with decreased adrenal 21alpha-hydroxylase activity.  The result is decreased cortisol production in obese individuals.  
Nathan Goodyear

Overtraining, Exercise, and Adrenal Insufficiency - 0 views

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    Great review on over training syndrome and hypoadrenia.
Nathan Goodyear

DISTRIBUTION OF ASCORBIC ACID, METABOLITES AND ANALOGUES IN MAN AND ANIMALS - Hornig - ... - 0 views

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    The tissues that have the highest concentrations of vitamin C are adrenal, pituitary, brain, heart, pancrease, and kidneys.
Nathan Goodyear

HPA Axis Reactivity and Lymphocyte Glucocorticoid Sensitivity in Fibromyalgia Syndrome ... - 0 views

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    Individuals with Fibromyalgia shown to have lowered salivary cortisol levels.  This study suggested that this could be due to reduced adrenal reactivity to ACTH.  Another thought, is there increased metabolism of cortisol in these clients.  This would be found in the urinary metabolites.
Nathan Goodyear

Diurnal variation of adrenocortical activ... [Neuropsychobiology. 1998] - PubMed - NCBI - 0 views

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    adrenocortical dysfunction found to play a role in CFS
Nathan Goodyear

Late-night and low-dose dexamethasone-suppressed cortisol in saliva and serum for the d... - 1 views

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    diagnostic accuracy again proven for salivary cortisol. So why does BCBS consider this experimental?  Maybe they just don't read research.
Nathan Goodyear

Utility of Salivary Cortisol Measurements in Cushing's Syndrome and Adrenal Insufficiency - 1 views

  • It is expected that the use of the measurement of salivary cortisol will become routine in the evaluation of patients with disorders of the HPA axis.
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    Salivary cortisol testing shown to have sensitivity and specificity that exceeds 90%.  Final Quote: "salivary cortisol will become routine in the evaluation of patients with disorders of the HPA axis
Nathan Goodyear

Adipose Tissue as an Endocrine Organ - 0 views

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    You need to look at your fat differently.  It literally has developed a life of its own.  Adipose Tissue functions as an endocrine organ.  Just like your thyroid, adrenals...
Nathan Goodyear

The Relationships Between Testosterone, Body Composition, and Insulin Resistance - 0 views

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    case study that showed removal of testosterone secreting adrenal tumor worsened insulin function and contributed to weight gain 9 months post surgery.  This is a case study and far from conclusive.
Nathan Goodyear

Mechanisms mediating androgen receptor reactivation after castration - 0 views

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    In cases of CRPC, there is endogenous androgen synthesis from weaker adrenal androgens.  Also, the authors point to a unregulated AR sensitivity in the lower androgen environment created by ADT.
Nathan Goodyear

Intratumoral De Novo Steroid Synthesis Activates Androgen Receptor in Castration Resist... - 0 views

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    adrenal androgens contribute to ADT resistant prostate cancer as precursors to T and DHT production.
Nathan Goodyear

Dietary Macronutrient Content Alters Cortisol Metabolism Independently of Body Weight C... - 0 views

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    Extra-adrenal cortisol production is increased by 11-Beta-HSD1 via low Carb diet.  This is counter to that seen in mice studies.  The fat content of the diet could explain this.  This study looked at men.
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