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Nathan Goodyear

Low Grade Chronic Inflammation in Women with Polycystic Ovarian Syndrome - 0 views

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    Women with PCOS have associated increased inflammation.  This origin is primarily via adipose tissue and associate adipocytokines (TNF-alpha, and IL-6).  CRP elevation, as found in this study, is associated with increased CVD.
Nathan Goodyear

Alterations in diurnal salivary cortisol rhyth... [Psychosom Med. 2008] - PubMed - NCBI - 0 views

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    Individuals with CFS found to have flattened salivary cortisol 4-point pattern and elevated IL-6.
Nathan Goodyear

Estradiol and inflammatory markers in Older Men - 0 views

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    In this study, estradiol is associate with increased IL-6 in elderly men. No correlation was seen with TNFalpha, and CRP.
Nathan Goodyear

Aromatase activity and interleukin-6... [J Clin Endocrinol Metab. 1995] - PubMed - NCBI - 0 views

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    Inflammatory cytokine, IL-6, shown to increase aromatase activity in breast cancer.
Nathan Goodyear

Full Text: Editorial - 0 views

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    high aromatase activity and conversion of testosterone to estrogen conversion plays a role in lupus and RA.  Inflammatory cytokines are shown to increase aromatase activity.
Nathan Goodyear

Does increased aromatase activity in adipose fibroblasts cause low sexual desire in pat... - 0 views

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    increased testosterone to estrogen conversion, in part, stimulated by inflammatory cytokines: TNF, and IL-6.  They propose aromatase inhibition to decrease testosterone to estrogen conversion.  This study looked at individuals with HIV.
Nathan Goodyear

Sex hormones influence on the immune system: basic and clinical aspects in autoimmunity - 0 views

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    high conversion of testosterone to estrogen conversion in men is from increased aromatase activity.  Inflammatory cytokines, such as IL-6, TNF-alpha, has been shown to increase aromatase activity and at the same time increase IL-6 and other inflammatory cytokines is the result of increased aromatase activity.
Nathan Goodyear

IL-6 in autoimmune diseas... [Cytokine Growth Factor Rev. 2002 Aug-Oct] - PubMed - NCBI - 0 views

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    IL-6 over expression associated with autoimmune disease.
Nathan Goodyear

Low Testosterone Levels and Increased Inflammatory Markers in Patients with Cancer and ... - 0 views

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    low testosterone and elevated IL-6 and CRP found in male cancer patients.
Nathan Goodyear

The effect of testosterone replacement therapy on adipocytokines and C-reactive protein... - 0 views

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    low testosterone correlated with elevated IL-6 and CRP in this study.  Translation: low Testosterone = inflammation
Nathan Goodyear

Estradiol and Inflammatory Markers in Older Men - 0 views

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    Estradiol found to be associate, though weakly, with IL-6 in men.  This provides a link between estradiol production in men and inflammation.
Nathan Goodyear

Reduction of Inflammatory Cytokine Concentrations and Improvement of Endothelial Functi... - 0 views

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    adipose tissue releases inflammatory markers (cytokines IL-6, TNF-alpha, V-CAM-1, ICAM-1, and P-selectin). Associated endovascular disfunction and eventually cardiovascular disease.  A direct link between obesity induced inflammation and endovascular dysfunction.  Weight loss in these obese women reduced secretion of the associated inflammatory cytokines and thus decreased vascular dysfunction.
Nathan Goodyear

Elevated Levels of Interleukin 6 Are Reduced in Serum and Subcutaneous Adipose Tissue o... - 0 views

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    weight loss resulted in reduction in IL-6 and leptin.  The reduction of IL-6 reflects a decrease in inflammation. The reduction in leptin reflects an improved leptin sensitivity.
Nathan Goodyear

Increased Toll-Like Receptor Activity in Patients With Metabolic Syndrome - 0 views

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    TLR2 and TLR4 are increased in patients with metabolic syndrome.  No surprise that IL-1Beta, IL-6, IL-8, TNF-alpha were increased as well.
Nathan Goodyear

Endotoxemia-induced inflammation and the effect on... [Crit Care. 2010] - PubMed - NCBI - 0 views

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    LPS endotoxemia shown to induce brain inflammation.  In this study, the inflammatory cytokine upregulation did not fully explain the septic encephalopathy so often found.  It was associated with elevated cortisol, which has been shown to shrink the hippocampus
Nathan Goodyear

Hypocortisolism and increased glucocorticoid... [Biol Psychiatry. 2004] - PubMed - NCBI - 0 views

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    low cortisol and elevated LPS, IL-6, and TNF-alpha found in people with PTSD.
Nathan Goodyear

Low Cortisol, High DHEA, and High Levels of Stimulated TNFα, and IL-6 in Wome... - 0 views

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    low cortisol pattern with elevated DHEA found in women with PTSD.  Additionally, elevated levels of TNF-alpha and IL-6 were found. Hormone evaluation was tested through saliva.
Nathan Goodyear

Effects of supplemental vitamin D and calcium on biomarkers of inflammation in colorect... - 0 views

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    Vitamin D3 shown to reduce CRP, TNF, IL-6, IL-1B, IL-8 in colorectal adenoma patients. This study supports the anti-inflammatory, anti-cancer benefits of vitamin D3.
Nathan Goodyear

IOS Press - Journal Article - 0 views

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    neuroinflammaiton, also described as excitotoxicity, found in the brains of children/young adults that lived in high air pollution areas.  Neuroinflammation (IL-6, IL-1, TNF-alpha, IFN-gamma...) found in the brains of these children and young adults.  This is the same process found in Alzheimers and other excitotoxicity disease states.  Addtionally, it is also involved in most chronic diseases of aging.
Nathan Goodyear

Sleep Duration and Biomarkers of Inflammation - 0 views

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    shortened sleep interval increased TNF-alpha levels and prolonged sleep intervals increased IL-6 and CRP.  It appears that sleep duration has a direct effect on inflammation
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