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Nathan Goodyear

Relationships between serum free ... [J Child Psychol Psychiatry. 1996] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...8682903

fatty acids Omega-3 fish oil zinc ADHD children pediatrics

shared by Nathan Goodyear on 06 Sep 11 - No Cached
  • Nathan Goodyear on 06 Sep 11
     
    free fatty acids and zinc shown to improve symptoms of ADHD in children after testing confirmed deficiencies.
Nathan Goodyear

Effects of supplemental fish oil on resting metabo... [J Int Soc Sports Nutr. 2010] - P... - 0 views

www.ncbi.nlm.nih.gov/...20932294

saliva salivary cortisol hormone testing Omega-3 weight loss overweight obese

shared by Nathan Goodyear on 13 Jul 11 - No Cached
  • These changes were significantly correlated with a reduction in salivary cortisol following FO treatment.
  • 6 wk of supplementation with FO significantly increased lean mass and decreased fat mass
  • Nathan Goodyear on 13 Jul 11
     
    saliva cortisol evaluation reflective of decreased fat mass with Omega-3 supplementation
Nathan Goodyear

Omega-3 fatty acids in juvenile idiopathic ar... [Clin Rheumatol. 2011] - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...21922187

Omega-3 n-3 Fish oil inflammation idiopathic arthritis NSAIDS IL-1 TNF-alpha fatty acids

shared by Nathan Goodyear on 21 Oct 11 - No Cached
  • Nathan Goodyear on 21 Oct 11
     
    Omega-3 intake reduced inflammation and pain in Juvenile idiopathic arthritis.  Associated inflammatory markers were decreased in study.  Anti-inflammatory drug usage was decreased as well.
Nathan Goodyear

European Journal of Clinical Nutrition - Effect of maternal n-3 long-chain polyunsatura... - 0 views

www.nature.com/...ejcn2014158a.html

nutrition n-3 omega 3 omega-3 fish oil pregnancy childhood obesity

shared by Nathan Goodyear on 22 Dec 14 - No Cached
  • It is estimated that approximately 30% of children and adolescents in the United States and about 15–30% of those in Europe can be classified as overweight or obese
  • An increasing body of evidence now suggests that the nutritional environment encountered in utero and the early postnatal life may elicit permanent alterations in adipose tissue structure or function and, thereby, programme the individual’s propensity to later obesity
  • The composition of fatty acids in the Western diets has shifted toward an increasing dominance of n-6 relative to n-3 LCPUFAs over the past decades.9,10 This shift is also reflected in the fatty acid composition of breast milk
  • ...8 more annotations...
  • Evidence from animal studies suggests that the n-6 LCPUFA arachidonic acid promotes adipose tissue deposition, whereas the n-3 LCPUFAs eicosapentaenoic acid and docosahexaenoic acid seem to exert an opposite effect
  • Overall, no effect of supplementation was found on BMI in preschool (<5 years) and school-aged (6–12 years) children
  • increased adiposity, once established in childhood, tends to track into adulthood
  • Many studies have shown that even children <2 years with a high BMI are at increased risk of developing obesity later in life
  • The acquisition of fat cells early in life appears to be an irreversible process
  • Evidence from cell culture and animal studies suggests that early exposure to n-3 LCPUFAs has the potential to limit adipose tissue deposition mainly by attenuating the production of the arachidonic acid metabolite prostacyclin, which has been shown to enhance adipogenesis
  • In conclusion, there is currently no evidence to support that maternal n-3 LCPUFA supplementation during pregnancy and/or lactation exerts a favourable programming effect on adiposity status in childhood
  • our systematic review highlights that most of the trials reviewed were prone to methodological limitations
  • Nathan Goodyear on 22 Dec 14
     
    Literature review finds limited data (9 studies, only 6 RCTs) of omega-3 during pregnancy.  No data was found that supported reduced obesity in children by mothers taking n-3 during pregnancy.  No harm was found either.  Data was sparse.   Take home: not enough data, no harm to pregnancy, children, thus if indications are present for mother, then recommend n-3.  At this point not studies have pointed to reduced obesity in children.
Nathan Goodyear

Omega-3 fatty acids in inflammation and autoimmune diseases. - PubMed - NCBI - 0 views

www.ncbi.nlm.nih.gov/...12480795

omega 3 omega-3 fish oil inflammation autoimmune disease

shared by Nathan Goodyear on 07 Feb 16 - No Cached
  • Nathan Goodyear on 07 Feb 16
     
    review article finds omega-3 supplementation reduced inflammation in autoimmune disease.
Nathan Goodyear

Omega-3 Fatty Acids and Inflammatory Processes - 0 views

www.ncbi.nlm.nih.gov/...PMC3257651

fats nutrition diet omega 3 inflammation NF-kappaB TNF-alpha omega-3 fish oil DHA EPA docosahexaenoic acid eicosapentaenoic acid

shared by Nathan Goodyear on 15 Sep 17 - No Cached
  • marine n-3 PUFAs have also been shown to alter the production of inflammatory proteins including chemokines, cytokines, growth factors and matrix proteases
  • Two transcription factors that are likely to play a role in inflammation are nuclear factor κ B (NFκB) and PPAR-γ
  • NFκB is the principal transcription factor involved in upregulation of inflammatory cytokine, adhesion molecule and cyclooxygenase-2 genes
  • ...3 more annotations...
  • PPAR-γ, is believed to act in an anti-inflammatory manner
  • PPAR-γ directly regulates inflammatory gene expression, it also interferes with the activation of NFκB creating an intriguing interaction between these two transcription factors
  • Both NFκB and PPAR-γ may be regulated by n-3 PUFAs.
  • Nathan Goodyear on 15 Sep 17
     
    great review of the anti-inflammatory effects of omega 3 DHA and EPA.  EPA inhibits COX and 5-LOX and their downstream prostaglandin and leukotrienes.  EPA/DHA inhibited endotoxin-stimulated IL-6, IL-8,TNF-alpha, and NFkappaB.
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