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Nathan Goodyear

Omega-3 fatty acids (fish oil) as an anti-inflam... [Surg Neurol. 2006] - PubMed - NCBI - 0 views

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    omega-3 equivalent to NSAIDS in pain management and inflammation
Nathan Goodyear

Is the use of cholesterol in mortality ris... [J Eval Clin Pract. 2011] - PubMed - NCBI - 0 views

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    cholesterol in women up to 270 is beneficial on CVD, not harmful.  How much does the difference in diet and lifestyle play a role here.  Norwegians have a higher fish intake, but they have a lower sun exposure. Maybe, just maybe, all pub around cholesterol has been overblown.
Nathan Goodyear

Fish Intake, Contaminants, and Human Health | Nutrition | JAMA | The JAMA Network - 0 views

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    Study finds that higher omega 3 intake over time associated with a reduction in blood clots, heart arrhythmias, lower triglycerides, lower heart rates and lower blood pressure.
Nathan Goodyear

Omega-3 fatty acids supplementation improves endothelial function and maximal oxygen up... - 0 views

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    supplementation of 2.6 grams of n-3 found to increase NO and VO2max in elite cycling athletes.  This has applications for all endurance athletes.  
Nathan Goodyear

Articles | Physiological Reports - 0 views

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    4 grams of daily n-3 decreased pulse wave velocity--decreased arteriosclerosis.  No change in blood pressure noted through the change in central pulse pressure.
Nathan Goodyear

Evaluation of Lipid Profiles and the Use of Omega-3 Essential Fatty Acid in Professiona... - 0 views

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    82% of retired NFL players <50 have statistically significant more blockage of arteries than the general population.    n-3 in this study was shown to improve the lipid profile in these individuals.  Inflammation needs to be addressed
Nathan Goodyear

Purified eicosapentaenoic and docosahexaenoic acids have differential effects on serum ... - 0 views

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    EPA and DHA have differing effects in men with Hyperlipidemia.  DHA increased LDL particle size, increased fasting insulin, but did not increase fasting glucose.
Nathan Goodyear

Docosahexaenoic Acid but Not Eicosapentaenoic Acid Lowers Ambulatory Blood Pressure and... - 0 views

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    Only DHA, not EPA, reduced blood pressure and heart rate.
Nathan Goodyear

Alpha lipoic acid is an anti-inflammatory and neuroprotective - 0 views

  • Data from cell culture and animal models suggest that LA could be combined with nutraceuticals such as curcumin, (-)-epigallocatechin gallate (from green tea) and docosahexaenoic acid (from fish oil) to synergistically decrease oxidative stress, inflammation
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    Alpha lipoic acid suggested via animal studies to be possible mechanism to prevent Alzhemiers disease.
Nathan Goodyear

Inuit are protected against... [Cancer Epidemiol Biomarkers Prev. 2003] - PubMed - NCBI - 0 views

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    Low incidence of prostate cancer in epidemiology study of Inuit eskimos.
Nathan Goodyear

Prophylactic and therapeutic effects of n-3 polyunsaturated fatty acids, capsaicin, and... - 0 views

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    Rat study, but it finds that n-3, capsaicin, and curcumin can not only decrease the inflammation associatied with arthritis, but it can delay it all together.
Nathan Goodyear

Effect of the long-term feeding of dietary lipids on the learning ability, fatty acid c... - 0 views

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    mouse study finds high DHA diet improved learning.
Nathan Goodyear

DHA dietary supplementation enhances the effects of exercise on synaptic plasticity and... - 0 views

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    DHA enriched diet plus exercis improved cognition through a increase in brain derived neurotrophic factor (BDNF).  The result was increased neuroplasticity.  Additionally, they were shown to reduce hippocampal lipid peroxidation.
Nathan Goodyear

Omega-3 fatty acid supplementation and reduction... [J Neurosurg. 2011] - PubMed - NCBI - 0 views

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    Animal model shows that n-3 intake reduced axonal injury after injury insult.  This implies a use in n-3 intake even after an insult has occured. This implies a role for n-3 in neuroplasticity.
Nathan Goodyear

ω-3 Fatty Acid Supplementation as a Potential Therapeutic Aid for the Recover... - 0 views

  • There is a growing body of preclinical literature suggesting that ω-3 FAs, and DHA in particular, may play a therapeutic role in mTBI
  • the potential for ameliorating or possibly even preventing the complications associated with concussions
  • DHA is the predominant ω-3 FA present in the brain, and, consistent with this finding, DHA, and not EPA, has been demonstrated to be critical for brain development and cognitive function throughout life
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  • the concentration of EPA in the brain is negligible (77–80), suggesting that EPA plays a limited role in mediating the beneficial effects of LCPUFA supplementation on mTBI pathology
  • there is evidence that the amount of DHA in brain tissue is decreased after mTBI (65, 66), suggesting an elevated need for DHA in mTBI recovery.
  • the current state of the science regarding LCPUFA supplementation for the treatment of concussion is based primarily on animal models
  • the well-established role of DHA in supporting the structure and function of the brain throughout the lifespan (26, 27, 46, 47, 53) provides encouragement that LCPUFAs may also prove beneficial in the context of concussion recovery.
  • no therapies are currently available to aid the recovery from this injury
  • Previously discussed reports outlining the use of ω-3 FAs in the recovery from severe TBIs (reviewed in Ref. 92) described the use of very-high doses of LCPUFAs (16.2 g/d EPA plus DHA) in the recovery of these patients
  • Within the context of mTBIs/concussions, translating a DHA intake used in several rat studies of mTBI recovery (40 mg ⋅ kg−1 ⋅ d−1 DHA) (57, 63, 64) using body surface area conversion methods (93) amounts to an estimated human intake of 387 mg/d DHA
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    nice review of the evidence of n-3, particularily DHA, in concussions and concussion recovery.
Nathan Goodyear

Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) - Nutrition and Traumatic Br... - 0 views

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    Evidence does support that n-3 reduces inflammation; yet limited evidence exists to provide direct evidence that n-3 protects against TBI.
Nathan Goodyear

Unbound MEDLINE | Pilot, Prospective, Randomized, Double-masked, Placebo-controlled Cli... - 0 views

  • the average tear production and tear volume was increased in the omega-3 group
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    Omega-3 supplementation possible therapy for dry eyes
Nathan Goodyear

Arch Intern Med -- Abstract: Effect of Different Antilipidemic Agents and Diets on Mort... - 0 views

  • Statins and n-3 fatty acids are the most favorable lipid-lowering interventions with reduced risks of overall and cardiac mortality.
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    Omega-3 most favorable lipid lowering agent
Nathan Goodyear

ingentaconnect Immunonutrition in Surgical Patients - 0 views

  • Surgery induces an inflammatory response
  • A range of nutrients, including several amino acids, antioxidant vitamins and minerals, ω-3 fatty acids, and nucleotides, are able to modulate inflammation and the associated oxidative stress, and maintain or improve immune function
  • parenteral glutamine is recommended in patients receiving parenteral nutrition
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  • Antioxidants, particularly selenium, should be considered for critically ill patients
  • enteral formulas enriched with fish oils are recommended for patients with acute respiratory distress syndrome.
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    nutrition to improve inflammation in surgical patiens
Nathan Goodyear

n-3 Polyunsaturated fatty acids, inflammation, and inflammatory diseases - 0 views

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    Take omega-3 to reduce inflammation!
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