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Nathan Goodyear

Use of Zinc as a Treatment for Tr... [Neurorehabil Neural Repair. 2012] - PubMed - NCBI - 0 views

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    Another study showing benefit of Zn in TBI
Nathan Goodyear

Improving treatments and outcomes: an emerging role... [Nutr Rev. 2012] - PubMed - NCBI - 0 views

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    Zinc emerging as a tool in the treatment/recovery of TBI
Nathan Goodyear

Exercise normalizes levels of MAG and Nogo-A growth inhibitors after brain trauma - Chy... - 0 views

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    exercise aids repair after TBI through BDNF.
Nathan Goodyear

The epidemiology of sports-related tra... [J Head Trauma Rehabil. 1998] - PubMed - NCBI - 0 views

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    analysis of sports related TBI
Nathan Goodyear

Immunoexcitotoxicity offers new insight in brain injury related research, care - 0 views

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    Great, though brief, review of immunoexcitotoxicity as it relates to CTE.
Nathan Goodyear

Occurrence of pituitary dysfunction following ... [J Neurotrauma. 2004] - PubMed - NCBI - 0 views

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    pituitary dysfunction found in people with TBI.  This study found the greatest effect on HGH.
Nathan Goodyear

Immunoexcitotoxicity as a central mechanism in chronic traumatic encephalopathy--A unif... - 0 views

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    Article discusses the immunoexcitotoxic process involved in chronic TBI. This is likely to be the underlying process involved in NFL and other football players delayed neurological effects. A similar process has been see in combat veterans returning from the theatre.
Nathan Goodyear

Progesterone neuroprotection in trauma... [Front Neuroendocrinol. 2009] - PubMed - NCBI - 0 views

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    Progesterone has a neuroprotective and promyelinating effects in the nervous system.  Progesterone increases BDNF.  Progesterone increases proliferation and differentiation of oligodendrocyte progenitor cells which will increase myelin production.
Nathan Goodyear

The molecular basis of neurodegeneration in multiple sclerosis - 0 views

  • Inflammation is the most predominant feature during the early (relaping) phases of the disease and declines with aging of the patients and disease duration
  • in the process of oligodendrocyte destruction and demyelination in MS lesions iron is liberated from its intracellular ferritin bound stores into the extracellular space, where it is taken up by microglia and macrophages and again stored together with ferritin. When this happens in MS lesions in an environment, where free radicals are produced by oxidative burst, iron can be liberated from ferritin and transformed into reactive Fe++[114], which reacts with hydrogen peroxide to generate highly reactive hydroxyl radicals [36] and thus amplifies oxidative damage and associated cellular injury
  • anti-inflammatory or immunomodulatory treatments are effective in the relapsing stage, but the benefit is lost when the patients have entered the progressive phase
  • ...1 more annotation...
  • Inflammation will remain a key target, since the data suggest that microglia activation and oxidative burst is driven by inflammation throughout all stages of the disease.
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    Very nice review of the neurodegenerative process in MS.  
Nathan Goodyear

Methylmercury induces oxidative injury, alterations in permeability and glutamine trans... - 0 views

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    methylmercury mediates neurotoxicity via mitochondrial damage, inflammation, and oxidative stress.  Astrocytes accumulated the methyl mercury.  The destruction of the astrocytes will result in an increase in glutamate.  Methylmercury is synergistic with other toxins in the development of immunoexcitotoxicity.
wheelchairindia9

Tricycle For Disabled Children - 0 views

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    The tricycles are individually designed to meet the needs of each disabled child and help provide physiotherapy, build muscle tone and promote play. Italso help benefit growth and development in children with disabilities, enabling them to keep active and retain their independence. Disabled children get huge physical and emotional benefits from having the specially tricycles, which are each custom made to suit the individual child's needs. Riding a tricycle provides both fun and fitness, and is a therapeutic activity that allows children to exercise their lower extremities. As the muscles move through cycling motions, they are flexed, extended and stretched. This range of motion is crucial for children with disabilities, because muscles are incapable of keeping up with bone growth unless fully extended. Tricycles are provided to severely disabled children and adults and come in two sizes, 20 inch and 24 inch models. These trikes are grant funded and to qualify for one of these, an individual must suffer from a condition such as, but not limited to, Cerebral Palsy, Down Syndrome, Traumatic Brain Injury or Autism. Trunk support system is ideal for riders who have trouble remaining upright while seated. An optional headrest is available. A headrest can be purchased with either a flat or contoured headpiece, and adjusts both horizontally and vertically for optimum positioning. The Front Pulley System maintains a level pedal position for children whose extreme tone forces the front of the pedal downward. Turn the oval knob to raise and lower the handlebar. A handbrake for the conventional handlebar will arrive installed on Large tricycle. Open access combined with a low transfer step makes it easy to get on and off trikes. Tricycle Deluxe Double Hand Drive: Frame : Made by E.R.W. Tubes 38.0 mm-16 G. 25.4 mm & 22.22 mm- 18 G. Seat & Back : M S, C.R.C. Sheet. Seat Size 18"x 16" Wheel Size : Wheel Diameter 24"x 1 1/2" Tyre and Tube Standard Company. Pa
Nathan Goodyear

Concussions' Lingering Effects Linked to Hormone Deficiency - Scientific American - 0 views

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    Scientific American article from 2013 highlights the link between head trauma and pituitary dysfunction.  
Nathan Goodyear

https://www.cns.org/sites/default/files/clinical_neuro/Chapter18_0.pdf - 0 views

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    Human study: High dose IV vitamin C and IM vitamin E shown to improve outcome.
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