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Nathan Goodyear

Intravenous methylcobalamin treatment for uremic ... [Intern Med. 1999] - PubMed - NCBI - 0 views

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    IV vitamin B12 shown to safe and effective treatment of neuropathy in diabetic patients.
Nathan Goodyear

Randomized, double-blind, pilot evaluation of int... [Mov Disord. 2009] - PubMed - NCBI - 0 views

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    IV glutathione shown to be same and provide mild improvement in Parkinson's disease.  This is a small pilot study, but a good place to start.  The likelyhood is that glutathione is more beneficial early in Parkinson's disease to slow disease progression.
Nathan Goodyear

Practicalities of glutathione supplementation in nutritional... : Current Opinion in Cl... - 0 views

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    high dose IV glutathione proven to be safe
Nathan Goodyear

Glutathione reduces the toxicity and improves quality of life of women diagnosed with o... - 0 views

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    IV glutathione reduces the toxicity of cisplatin in women treated for ovarian cancer.  Quality of life also improved
Nathan Goodyear

The Effect of Glutathione and N-Acetylcysteine on Lipoperoxidative Damage in Patients w... - 0 views

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    IV glutathione and NAC shown to reduce oxidative stress markers associated with septic shock
Nathan Goodyear

Glutathione (GSH) improved haemostatic an... [Drugs Exp Clin Res. 1992] - PubMed - NCBI - 0 views

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    IV glutathione shown to reduce blood viscosity and platelet aggregation.  THis has major implications in atherosclerosis and CVD
Nathan Goodyear

Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a p... - 0 views

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    IV vitamin C shown to be useful aid in cancer treatment
Nathan Goodyear

Vitamin C Pharmacokinetics: Implications for Oral and Intravenous Use - 0 views

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    only high dose IV vitamin C shown to produce high plasma vitamin C concentrations compared to oral vitamin c.
Nathan Goodyear

The effect of intravenous vitamin C infusion on periprocedural myocardial injury for pa... - 0 views

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    IV vitamin C, though low dose, is associated with a reduced myocardial injury.  Not only safe, but benefit is seen in protecting the heart against repercussion injury.
Nathan Goodyear

Thieme eJournals - Abstract - 0 views

  • ur data showed that sHT patients exists impaired endothelial function, and antioxidant alpha-lipoic acid can improve endothelial function, through decrease of oxygen- derived free radicals.
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    IV alpha Lipoic acid shown to improve vascular function
Nathan Goodyear

Alpha-lipoic acid improves vascular endothelial function in patients with type 2 diabet... - 0 views

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    IV alpha lipoic acid improves vascular function
Nathan Goodyear

Tumor cells have decreased ability to metabolize H2O2: Implications for pharmacological... - 0 views

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    Cancer cells have reduced catalase activity and thus reduced capability to metabolize H202. IV vitamin takes advantage of this deficiency.
Nathan Goodyear

Ascorbic acid: Chemistry, biology and the treatment of cancer - 0 views

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    IV vitamin C as an adjuvant in the treatment of cancer.
Nathan Goodyear

High-dose intravenous vitamin C in the treatment of a patient with renal cell carcinoma... - 0 views

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    This is a case study of a patient with cancer of the kidney treated with vitamin C. Therapy was obviously successive in obtaining remission.
Nathan Goodyear

JTM | Full text | Intravenous ascorbic acid to prevent and treat cancer-associated sepsis? - 0 views

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    Cancer patients are depeleted of vitamin C.  IV vitamin C is suggested as a therapy to treat sepsis or SIRS in those individuals with cancer.
Nathan Goodyear

Oral antibiotics for treating infection with Pseudomonas aeruginosa in people with cyst... - 0 views

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    Oral Antibiotics, no less effective than IV therapy.  This is a cochrane review of the treatment of p aeruginosa in those with CF.
Nathan Goodyear

Vitamin C: A Concentration-Function Approach Yields Pharmacology and Therapeutic Discov... - 0 views

  • when vitamin C is ingested by mouth, plasma and tissue concentrations are tightly controlled by at least 3 mechanisms in healthy humans: absorption, tissue accumulation, and renal reabsorption
  • 4th mechanism, rate of utilization, may be important in disease
  • Ascorbate administered intravenously has already been tested in a phase I clinical trial, is in wide use by complementary and alternative medicine (integrative medicine) practitioners, and appears to have minimal side effects in patients who are properly screened.
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    Fantastic review on IV Vitamin C therapy
Nathan Goodyear

The ROS-induced cytotoxicity of ascorbate is attenuated by hypoxia and HIF-1alpha in th... - 0 views

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    vitamin C effects decreased by hypoxia which increases HIF-1alpha.  The authors propose oxygen therapy, hyperbaric, to improve and augment the cytotoxic effects of vitamin C.
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