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International Journal of Bone and Rheumatology Research (IJBRR) ISSN 2470-4520 is a peer-reviewed, Open Access journal that combines the interests of researchers and clinical practitioners across Bone, Orthopedic medicine, microsurgery and congenital anomalies. IJBRR publishes high quality papers, rapid communications, original papers, research letters and case reports pertaining to clinical reports and clinical studies in basic and applied Bone & Rheumatology Research. For more details : http://scidoc.org/bone-and-rheumatology-research.php

Parathyroid carcinoma is a rare cause of primary hyperparathyroidism. When this malignancy is diagnosed, often there are distant metastases (usually liver and/or bone). Brown tumor is a localized form of osteitis fibrosa cystica; classic manifestation in bone of excess parathyroid hormone and this is a bening pathology. We encountered an unusual case of parathyroid carcinoma with images that mimicked metastatic bone tumors, whose differential diagnosis with brown tumor may be complicated. Positron emission tomography/computed tomography (PET/CT) scan was requested for the evaluation of fluorodeoxyglucosa uptake of these lesions. PET/CT images showed multiple hypermetabolic images that mimicked multiple skeletal metastasis but brown tumors could not be dismissed.

Lymphangiomatosis is rare in both adults and children. We present an 11 year old boy with right chylothorax. The formation of chylothorax was a result of diffuse lymphangioma in the mediastinum spreading to the pleura. In addition, this patient suffered from cystic bone lesions. The child was finally diagnosed as having lymphangiomatosis based on pleural biopsy and bone lesions found on CTs and MRI. He was treated by pleurectomy and propranol as well as control of anemia and infection. For more info : http://scidoc.org/IJRDM-01-101.php

Ankylosing Spondylitis (AS) is a chronic disease with inflammation at the enthesis of the spine and peripheral skeleton, which leads to bony erosion or juxtain sertional osteoporosis in the early stages. However, in later stages, new bone formation, syndesmophytes and ankylosis can occur. Generalized as well as regional osteopaenia is common in AS [1] with a frequency ranging from 50-92% [2-4]. It ranges from 41-62% in spine and 46-86% in femur [5]. For more information : http://scidoc.org/IJBRR-2470-4520-03-601.php