Scientists at the McEwen Centre for Regenerative Medicine and the Ontario Cancer Institute have isolated a human blood stem cell in its purest form: as a single stem cell capable of regenerating the entire blood system.
"This discovery means we now have an increasingly detailed road map of the human blood development system, including the much sought after stem cell," says principal investigator John Dick, who holds a Canada Research Chair in stem cell Biology and is a Senior Scientist at the McEwen Centre for Regenerative Medicine and the Ontario Cancer Institute, University Health Network (UHN).
"We have isolated a single cell that makes all arms of the blood system, which is key to maximizing the potential power of stem cells for use in more clinical applications. Stem cells are so rare that this is a little like finding a needle in a haystack," says Dr. Dick.
Ref.: John E. Dick, Isolation of Single Human Hematopoietic Stem Cells Capable of Long-Term Multilineage Engraftment, Science, July 2011: Vol. 333 no. 6039 pp. 218-221 [DOI: 10.1126/science.1201219]
In embryos and induced pluripotent stem cells, Nanog sets the ground state of pluripotency
Nanog, named after the fountain of eternal youth, is considered the key to pluripotency, but its role is puzzling: it can be deleted from embryonic stem cells without causing them to differentiate, and it is not among the collection of genes that can induce specialized cells to become pluripotent. Nonetheless, it does help human cells reprogram and can be used to separate incompletely reprogrammed cells from fully reprogrammed ones.
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SCDE is live
The Stem Cell Discovery Engine (SCDE) is an integrated platform that allows users to consistently describe, share and compare cancer and tissue Stem Cell data. It is made up of an online database of curated experiments coupled to a customized instance of the Galaxy analysis engine with tools for gene list manipulation and molecular profile comparisons. The SCDE currently contains more than 50 stem cell-related experiments. Each has been manually curated and encoded using the ISA-Tab standard to ensure the quality of the data and its annotation.
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The Center for Health Bioinformatics at the Harvard School of Public Health provides consults to researchers for the management, integration and contextual analysis of biological high-throughput data. We are a member of the Center for Stem Cell Bioinformatics, the Environmental Statistics and Bioinformatics Core at the Harvard NIEHS Center for Environmental Health and the Genetics & Bioinformatics Consulting group for Harvard Catalyst and work closely with our colleagues in the Department of Biostatistics and the Program in Quantitative Genomics to act as a single point of contact for computational biology,
Stem cell research has now proved that stem cells exist in the mind and the heart. Researchers in numerous labs are attempting to discover better approaches to make substantial amounts of adult stemcells and to control them to produce particular cell sorts so that, they can be utilized to treat damage or malady.
Scientific communities have clearly indicated that lack of stem cells highly affect the quality of life a person is living. Those who have more stem cells in the body always live the healthy and superior life.
ScienceDaily (Apr. 26, 2011) - In a paper published in the April 25 early online edition of the Proceedings of the National Academy of Sciences, researchers at the University of California, San Diego School of Medicine, the Gladstone Institutes in San Francisco and colleagues report a game-changing advance in stem cell science: the creation of long-term, self-renewing, primitive neural precursor cells from human embryonic stem cells (hESCs) that can be directed to become many types of neuron without increased risk of tumor formation.
Read the latest Stem Cell Research at Trivedi Effect! The Trivedi Effect's impact on cancer cells and how, it has become the alternate medicine for cancer.
Creative Bioarray provides various human and animal cell lines that are invaluable for medical, scientific and pharmaceutical institutions. Creative Bioarray offers Mouse Embryonic Stem Cells for your research.
Creative Bioarray provides various human and animal cell lines that are invaluable for medical, scientific and pharmaceutical institutions. Creative Bioarray offers Adult Stem Cells for your research.
Creative Bioarray provides various human and animal cell lines that are invaluable for medical, scientific and pharmaceutical institutions. Creative Bioarray offers Rat Embryonic Stem Cells for your research.
Differentiated human cells have been reprogrammed to an embryonic-like state with the addition of only one gene rather than the standard four. This should advance techniques for the efficient production of high-quality patient-specific stem cells.
Stem cells are generally present in the body of humans and several animals. They divide themselves into some other cells as well with time, which are important for the survival of humans.
Globs of human fat removed during liposuction conceal versatile cells that are more quickly and easily coaxed to become induced pluripotent stem cells, or iPS cells, than are the skin cells most often used by researchers, according to a new study from Stanford's School of Medicine.
A recent article in Scientific American questioned whether research on stem cell lines derived from unfertilized eggs was too tightly regulated by the federal government. Now that technology allows the creation of stem cells without fertilization, there is no question that federal laws and guidelines are overly restrictive, causing a detrimental effect on valuable scientific inquiry.
What happens to fat left over from a liposuction procedure? Brad Pitt might choose to turn it in to soap, but scientists at Stanford University have figured out a surprising alternative: stem cells.