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People keep blaming the emergence of HIV on science, or at least medicine. For the longest time this came in the form of the claim that it was all due to contaminated polio vaccine. That turned out to be factually groundless. Now a group of scientists in the US thinks it may all be down to the greatest medical intervention of all: the eradication of smallpox.

"A more potentially useful observation about HIV and viruses comes from Jennifer Smith of the University of North Carolina in Chapel Hill and colleagues in the 1 June issue of the Journal of Infectious Diseases, in which they report that men with HPV infection on their penis are nearly twice as likely to catch HIV than men without. They suspect the virus - which causes cervical cancer in women, and genital warts in men and women - attracts lymphocytes to the skin of the penis for HIV to infect, or creates micro-lesions where it can enter. That's good news, because we have a vaccine for HPV that appears to be completely safe. The team calculates that vaccinating men against HPV could prevent as many cases of HIV as more widely hailed circumcision efforts. It just goes to show that vaccination - already one of the biggest success stories of medicine - can continue to throw up unexpected benefits."

ScienceDaily (Jan. 6, 2011) - For parents wanting to reduce the negative influence of TV on their children, the first step is normally to switch off the television set. But a new study suggests that might not be enough. It turns out indirect media exposure, i.e., having friends who watch a lot of TV, might be even more damaging to a teenager's body image.

Cognitive-bias modification may put the psychiatrist's couch out of business

When a cycad is ready to reproduce, it grows a large colorful cone, rich with pollen or seed. It signals its readiness by radiating heat or sending out attractive odors to pollinators, who travel back and forth. Once fertilized, the seed-rich cone is ripped apart by hungry seed carriers (who've included over the years, not just birds and insects, but dinosaurs, pterosaurs, bats; these trees have been eaten by just about everybody). But what if you can't find a mate? The tree in London (and its clones that are now growing in botanical gardens all over the world) is a male. It can make pollen. But it can't make the seeds. That requires a female. Researchers have wandered the Ngoya forest and other woods of Africa, looking for an E. woodii that could pair with the one in London. They haven't found a single other specimen. They're still searching. Unless a female exists somewhere, E. woodii will never mate with one of its own. It can be cloned. It can have the occasional fling with a closely related species. Hybrid cycads are sold at plant stores, but those plants aren't the real deal. The tree that sits in London can't produce a true offspring. It sits there, the last in its long line, waiting for a companion that may no longer exist.

It's not quite Cyclops, the sci-fi superhero from the X-Men franchise whose eyes produce destructive blasts of light, but for the first time a laser has been created using a biological cell. The human kidney cell that was used to make the laser survived the experience. In future such "living lasers" might be created inside live animals, which could potentially allow internal tissues to be imaged in unprecedented detail. It's not the first unconventional laser. Other attempts include lasers made of Jell-O and powered by nuclear reactors (see box below). But how do you go about giving a living cell this bizarre ability? Typically, a laser consists of two mirrors on either side of a gain medium - a material whose structural properties allow it to amplify light. A source of energy such as a flash tube or electrical discharge excites the atoms in the gain medium, releasing photons. Normally, these would shoot out in random directions, as in the broad beam of a flashlight, but a laser uses mirrors on either end of the gain medium to create a directed beam. As photons bounce back and forth between the mirrors, repeatedly passing through the gain medium, they stimulate other atoms to release photons of exactly the same wavelength, phase and direction. Eventually, a concentrated single-frequency beam of light erupts through one of the mirrors as laser light.

Easy to understand evidence for a common ape-like human/chimp ancestor. One of thousands of collaborating pieces of evidence, but this one is very conceptual. Whip it out anytime a creationist starts preaching.

Physicists currently believe that most of the dark matter in the universe is made up of individual particles, and the challenge is to work out what kind of particles these are. New research, however, overturns this assumption and says that observational and experimental data are better explained if dark matter exists as composite particles - atoms of dark protons and dark electrons that are acted on by the dark-matter equivalent of the electromagnetic force.

Genomes aren't orderly and neat; they're exceedingly messy and complex, filled with "noise" from which subtle signals are difficult to filter. A disease can arise from one or two mutations, or from the cumulative action of hundreds. This means finding genome mutations responsible for diseases is both incredibly difficult and also often fruitless: The variation in individual genomes is so large that nearly every single potential disease-causing mutation typically turns out to be benign.

Fats in foods like potato chips and french fries make them nearly irresistible because they trigger natural marijuana-like chemicals in the body called endocannabinoids, researchers at the University of California, Irvine, have found. The researchers discovered that when rats tasted something fatty, cells in their upper gut started producing endocannabinoids, while sugars and proteins did not have this effect. How fats create, like, a buzz It starts on the tongue, where fats in food generate a signal that travels first to your brain, and then through a nerve bundle called the vagus to your intestines. There, the signal stimulates the production of endocannabinoids, which initiates a surge in cell signaling that prompts you to totally pig out - probably by initiating the release of digestive chemicals linked to hunger and satiety that compel us to eat more. And that leads to obesity, diabetes and cancer, the researchers said. But they suggest it might be possible to curb this process by obstructing endocannabinoid activity: for example, by using drugs that "clog" cannabinoid receptors. The trick: bypassing the brain to avoid creating anxiety and depression (which happens when endocannabinoid signaling is blocked in the brain). I'm guessing McDonald's won't be adding that drug to their fries. Ref.: Daniele Piomelli, et al., An endocannabinoid signal in the gut controls dietary fat intake, PNAS, 2011; in press

Listen up, Facebook and Twitter groupies: how easily can social pressure affect your memory? Very easily, researchers at the Weizmann Institute and University College London have proved, and they think they even know what part of the brain is responsible. The participants conformed to the group on these "planted" responses, giving incorrect answers nearly 70% of the time. Volunteers watched a documentary film in small groups. Three days later, they returned to the lab individually to take a memory test, answering questions about the film. They were also asked how confident they were in their answers. They were later invited back to the lab to retake the test. This time, the subjects were also given supposed answers of the others in their film-viewing group (along with social-media-style photos) while being scanned in a functional MRI (fMRI) that revealed their brain activity. Is most of what you know false? Planted among these were false answers to questions the volunteers had previously answered correctly and confidently. The participants conformed to the group on these "planted" responses, giving incorrect answers nearly 70% of the time. To determine if their memory of the film had actually undergone a change, the researchers invited the subjects back to the lab later to take the memory test once again, telling them that the answers they had previously been fed were not those of their fellow film watchers, but random computer generations. Some of the responses reverted back to the original, correct ones, but get this: despite finding out the scientists messed with their minds, close to half of their responses remained erroneous, implying that the subjects were relying on false memories implanted in the earlier session. An analysis of the fMRI data showed a strong co-activation and connectivity between two brain areas: the hippocampus and the amygdala. Social reinforcement could act on the amygdala to persuade our brains to replace a strong memory wi

Brain, bodily awareness, and the emergence of a conscious self: these entities and their relations are explored by Germanphilosopher and cognitive scientist Metzinger. Extensively working with neuroscientists he has come to the conclusion that, in fact, there is no such thing as a "self" -- that a "self" is simply the content of a model created by our brain - part of a virtual reality we create for ourselves. But if the self is not "real," he asks, why and how did it evolve? How does the brain construct the self? In a series of fascinating virtual reality experiments, Metzinger and his colleagues have attempted to create so-called "out-of-body experiences" in the lab, in order to explore these questions. As a philosopher, he offers a discussion of many of the latest results in robotics, neuroscience, dream and meditation research, and argues that the brain is much more powerful than we have ever imagined. He shows us, for example, that we now have the first machines that have developed an inner image of their own body -- and actually use this model to create intelligent behavior. In addition, studies exploring the connections between phantom limbs and the brain have shown us that even people born without arms or legs sometimes experience a sensation that they do in fact have limbs that are not there. Experiments like the "rubber-hand illusion" demonstrate how we can experience a fake hand as part of our self and even feel a sensation of touch on the phantom hand form the basis and testing ground for the idea that what we have called the "self" in the past is just the content of a transparent self-model in our brains. Now, as new ways of manipulating the conscious mind-brain appear on the scene, it will soon become possible to alter our subjective reality in an unprecedented manner. The cultural consequences of this, Metzinger claims, may be immense: we will need a new approach to ethics, and we will be forced to think about ourselves in a fundamentally new way. At

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