Memories 'geotagged' with spatial information - 0 views
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Using a video game in which people navigate through a virtual town delivering objects to specific locations, a team of neuroscientists
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has discovered how brain cells that encode spatial information form "geotags" for specific memories and are activated immediately before those memories are recalled.
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work shows how spatial information is incorporated into memories and why remembering an experience can quickly bring to mind other events that happened in the same place
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findings provide the first direct neural evidence for the idea that the human memory system tags memories with information about where and when they were formed
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The participants were first given a period where they were allowed to freely explore the city and learn the stores' locations
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When the game began, participants were only instructed where their next stop was, without being told what they were delivering
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After they reached their destination, the game would reveal the item that had been delivered, and then give the participant their next stop
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After 13 deliveries, the screen went blank and participants were asked to remember and name as many of the items they had delivered in the order they came to mind
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This allowed the researchers to correlate the neural activation associated with the formation of spatial memories (the locations of the stores) and the recall of episodic memories: (the list of items that had been delivered).
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"Having these patients play our games allows us to record every action they take in the game and to measure the responses of neurons both during spatial navigation and then later during verbal recall."
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By asking participants to recall the items they delivered instead of the stores they visited, the researchers could test whether their spatial memory systems were being activated
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During navigation, neurons in the hippocampus and neighboring regions can often represent the patient's virtual location within the town
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Using the brain recordings generated while the participants navigated the city, the researchers were able to develop a neural map that corresponded to the city's layout
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As participants passed by a particular store, the researchers correlated their spatial memory of that location with the pattern of place cell activation recorded
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With maps of place cell activations in hand, the researchers were able to cross- reference each participant's spatial memories as they accessed their episodic memories of the delivered items
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cannot distinguish whether these spatial memories are actually helping the participants access their episodic memories