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shared by Mars Base on 09 May 12 - No Cached

Blood samples are frozen in the Space Station’s freezer for preservation before being returned to Earth for analysis
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ROALD experiments are looking at why certain human cells replicate less in space
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New results from research on the International Space Station are offering clues on why astronauts’ immune systems don’t work as well in space
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discovered that a particular enzyme, called 5-LOX, becomes more active in weightlessness.  
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5-LOX enzyme in part regulates the life expectancy of human cells
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Blood samples from two healthy donors were sent to the orbital outpost
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One set was exposed to weightlessness for two days, while the other was held in a small centrifuge to simulate Earth-like gravity
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samples were then frozen and sent back to Earth for analysis.
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weightless samples showed more 5-LOX activity than the centrifuged samples
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centrifuged samples remained identical to the ground samples
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We now have a target enzyme
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e 5-LOX enzyme can be blocked with existing drugs, so using these findings to improve human health could be a close reality
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Research will continue
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follow-up experiment returned to Earth in a Soyuz capsule with the Expedition 30 crew last week
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Scientists will look for other changes in the cells to understand the underlying mechanisms fully.
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