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"SignalP 3.0 Server\n\nSignalP 3.0 server predicts the presence and location of signal peptide cleavage sites in amino acid sequences from different organisms: Gram-positive prokaryotes, Gram-negative prokaryotes, and eukaryotes. The method incorporates a prediction of cleavage sites and a signal peptide/non-signal peptide prediction based on a combination of several artificial neural networks and hidden Markov models.\n\nView the version history of this server. All the previous versions are available on line, for comparison and reference.\n\nNew paper about using SignalP and other protein subcellular localization prediction methods:\nLocating proteins in the cell using TargetP, SignalP, and related tools\nOlof Emanuelsson, Søren Brunak, Gunnar von Heijne, Henrik Nielsen\nNature Protocols 2, 953-971 (2007)."