Rheumatoid Arthritis is an incurable disease that is often difficult to treat. The article describes how a transfer of cultured synovial fibroblasts can increase the amount of IL-1Ra receptor, which offers a therapeutic gene that can be used to obtain intra articular transgene expression.
A long term foreign gene expression can be embedded/transferred if a housekeeping gene promoter is present to drive the transcription. A mouse embryo fibroblast implants can be achieved when the embryo is embedded in a collagen matrix, which is a proof of the theory.
Riboswitches, natural RNA sensors that mediate the control of gene expression by beinding with metabolites, are engineered via a simulation to meet the requirements of translational regulation in organelles. These new riboswitches are able facilitate the expression of chloroplast genes
Psychologists from the Buffalo University and University of California have conducted a survey to find out if DNA can affect how a person perceives the world. They conclude that there is a specific gene, which has not yet been identified, that controls the receptors of oxytocin and vasopressin, hormones that display "niceness".
Researchers in IMIM have discovered the function of the enzyme LOXL2, which is one of the factor causing cancer. The enzyme interacts with histone H3, and changes the DNA sequence around that histone, eliminating the lysine 4 amino acid group, which favors tumor development