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Sasicha Manupipatpong

New genes linked to brain size, intelligence - 2 views

  • genes that increase your risk for a single disease that your children can inherit
  • factors that cause tissue atrophy and reduce brain size, which is a biological marker for hereditary disorders
  • schizophrenia, bipolar disorder, depression, Alzheimer’s disease and dementia
  • ...13 more annotations...
  • sample large enough to reveal clear patterns in genetic variation and show how these changes physically alter the brain
  • smaller brains
  • gene variants that deplete brain tissue beyond normal in a healthy person
  • unearth new genetic variants in people who have bigger brains as well as differences in regions critical to learning and memory
  • screened the genomes of people suffering from a specific brain disease and combed their DNA to uncover a common variant.
  • consistent relationship between subtle shifts in the genetic code and diminished memory centers
  • variations in their DNA that help boost or lower their brains’ susceptibility to a vast range of diseases
  • People also can take preventive steps through exercise, diet and mental stimulation to erase the effects of a bad gene
  • Once we identify the gene, we can target it with a drug to reduce the risk of disease
  • genes that explain individual differences in intelligence
  • gene called HMGA2 affected brain size as well as a person’s intelligence
  • People whose HMGA2 gene held a letter “C” instead of “T” on that location of the gene possessed larger brains and scored more highly on standardized IQ tests
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    Specific genes have been identified which affect brain size and intelligence--a difference of one nucleotide in the DNA sequence could determine how well you score on a standardized IQ test.
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