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Statistical validation of results, as Shaffer described it, simply involves testing the null hypothesis: that the pattern you detect in your data occurs at random. If you can reject the null hypothesis—and science and medicine have settled on rejecting it when there's only a five percent or less chance that it occurred at random—then you accept that your actual finding is significant. The problem now is that we're rapidly expanding our ability to do tests. Various speakers pointed to data sources as diverse as gene expression chips and the Sloan Digital Sky Survey, which provide tens of thousands of individual data points to analyze. At the same time, the growth of computing power has meant that we can ask many questions of these large data sets at once, and each one of these tests increases the prospects than an error will occur in a study; as Shaffer put it, "every decision increases your error prospects." She pointed out that dividing data into subgroups, which can often identify susceptible subpopulations, is also a decision, and increases the chances of a spurious error. Smaller populations are also more prone to random associations. In the end, Young noted, by the time you reach 61 tests, there's a 95 percent chance that you'll get a significant result at random. And, let's face it—researchers want to see a significant result, so there's a strong, unintentional bias towards trying different tests until something pops out. Young went on to describe a study, published in JAMA, that was a multiple testing train wreck: exposures to 275 chemicals were considered, 32 health outcomes were tracked, and 10 demographic variables were used as controls. That was about 8,800 different tests, and as many as 9 million ways of looking at the data once the demographics were considered.

King's comments weren't recorded, but a staffer for Media Matters, who heard the comments, provided TPMmuckraker with an account. The staffer, who requested anonymity because she's not a communications specialist, said that King, an extreme right-winger with a reputation for eyebrow-raising rhetoric, appeared as a surprise guest speaker on an immigration panel at the conservative conference. During his closing remarks, King veered into a complaint about high taxes, and said he could "empathize" with the man who flew a plane into an IRS building last week. During the question and answer session, the Media Matters staffer asked King to clarify his comment, reminding him of his sworn duty to protect the American people from all sworn enemies, foreign and domestic. In response, said the staffer, King gave a long and convoluted answer about having been personally audited by the IRS, and ended by saying he intended to hold a fundraiser to help people "implode" their local IRS office.