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hamelinclara

Johnson And Johnson, Novartis, And AbbVie; Three Pharma Stocks That Could Be Good For Y... - 1 views

www.forbes.com/...cks-that-could-be-good-for-you

stocks pharma

shared by hamelinclara on 22 Jan 13 - No Cached
  • hat’s based on less patent exposure, improving pipelines, growing contributions from emerging markets, and cost cutting.
hamelinclara

2012 in reflection : Article : Nature Reviews Drug Discovery - 1 views

www.nature.com/...nrd3927.html

Patent

shared by hamelinclara on 09 Jan 13 - No Cached
  • Last year saw the largest loss of revenue yet from major drugs due to patent expiries, but a continuation of 2011's higher level of drug approvals and new initiatives to address R&D challenges provide hope for the future.
  • In September 2012, the non-profit TransCelerate BioPharma was established by Abbott, AstraZeneca, Boehringer Ingelheim, Bristol-Myers Squibb, Eli Lilly, GlaxoSmithKline, Johnson & Johnson, Pfizer, Genentech and Sanofi, initially to focus on improving clinical trial processes.
  • Incentives to develop breakthrough products were one of the major themes in the fifth incarnation of the US Prescription Drug User Fee Act (PDUFA), authorized in July 2012, through which industry pays fees to the FDA for product review (Nature Rev. Drug Discov. 11, 586–588; 2012).
hamelinclara

Ten Pharmaceutical Companies Unite to Accelerate Development of New Medicines -- PHILAD... - 1 views

www.prnewswire.com/...f-new-medicines-170329346.html

Pharma Research TransCelerate

shared by hamelinclara on 09 Jan 13 - No Cached
  • Ten leading biopharmaceutical companies announced today that they have formed a non-profit organization to accelerate the development of new medicines. Abbott, AstraZeneca, Boehringer Ingelheim, Bristol-Myers Squibb, Eli Lilly and Company, GlaxoSmithKline, Johnson & Johnson, Pfizer, Genentech a member of the Roche Group, and Sanofi launched TransCelerate BioPharma Inc. ("TransCelerate"), the largest ever initiative of its kind, to identify and solve common drug development challenges with the end goals of improving the quality of clinical studies and bringing new medicines to patients faster.
  • financial and other resources, including personnel, to solve industry-wide challenges in a collaborative environment.
  • among the heads of R&D at major pharmaceutical companies that there is a critical need to substantially increase the number of innovative new medicines,
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  • As shared solutions in clinical research and other areas are developed, TransCelerate will involve industry alliances including Clinical Data Interchange Standards Consortium (CDISC), Critical-Path Institute (C-Path), Clinical Trials Transformation Initiative (CTTI), Innovative Medicines Initiative (IMI), regulatory bodies including the US Food and Drug Administration (FDA) and European Medicines Agency (EMA), and Contract Research Organizations (CROs).
  • "We applaud the companies in TransCelerate BioPharma for joining forces to address a series of longstanding challenges in new drug development. This collaborative approach in the pre-competitive arena, utilizing the collective experience and resources of 10 leading drug companies and others to follow, has the promise to lead to new paradigms and cost savings in drug development, all of which would strengthen the industry and its ability to develop innovative and much-needed therapies for patients.
hamelinclara

L'industrie pharmaceutique attend beaucoup de 2013 - 0 views

www.usinenouvelle.com/...ttend-beaucoup-de-2013.N189571

Pharma 2013 stratégies

shared by hamelinclara on 26 Jan 13 - No Cached
  • Que ce soit le cancer, le diabète, les maladies cardio-vasculaires, la sclérose en plaques ou les hépatites, les laboratoires pharmaceutiques misent sur nombre de "blockbusters", de nouveaux médicaments sur lesquels ils misent beaucoup.
  • Roche, GlaxoSmithKline, Eli Lilly, Biogen Idec, Gilead Sciences et Novo Nordisk figurent parmi les laboratoires disposant de nouveaux produits atteignant une phase cruciale de développement en 2013.
  • Le diabète devrait également faire l'objet de nouveaux traitements, malgré le rejet par la FDA de médicaments à base de dapagliflozine, inhibiteur de SGLT2 pour le traitement du diabète de type 2, proposés par AstraZeneca et Bristol Meyers.Johnson & Johnson devrait obtenir le feu vert de la FDA pour sa canagliflozine, déjà approuvée par un panel d'experts la semaine passée, alors que le marché du SGLT2 pèsera quelque 7 milliards de dollars en 2020, selon Damien Conover, analyste de Morningstar.
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  • "La productivité est en train de dépasser le point critique, mais l'autre grande question est de savoir si l'industrie peut obtenir les prix qu'elle veut pour les nouveaux produits", explique-t-il.
  • Leader du marché du diabète, Novo Nordisk mise de son côté sur une nouvelle insuline à effet prolongé, appelée Tresiba, pour maintenir ses concurrents à distance. Et le groupe a également de bonnes chances de succès sur le marché du traitement de l'obésité, s'il réussit à prouver que son liraglutide est sans danger et efficace dans la perte de poids.Pour ce qui concerne le cancer, qui mobilise les investissements en recherche et développement (R&D) les plus lourds, le ramucirumab d'Eli Lilly est particulièrement attendu, d'autant que le laboratoire sera confronté à l'arrivée à terme du brevet de son antidépresseur Cymbalta en décembre.Eli Lilly dispose par ailleurs de 13 médicaments en phase III de développement, un record pour ce groupe pharmaceutique.Roche compte lui conserver sa place de leader du marché du cancer avec l'approbation attendue en 2013 du T-DEM1, destiné à traiter le cancer du sein.Enfin, avec six nouveaux médicaments pour le traitement des affections pulmonaires, du diabète, du cancer et du sida en attente d'approbation et deux traitements pour les maladies cardio-vasculaires et le cancer en phase III, GlaxoSmithKline est peut-être le groupe pharmaceutique qui attend le plus de 2013.
hamelinclara

Pharma industry's most productive innovators recognised - 0 views

ideapharma.com/...oductive-innovators-recognised

industry pharma

shared by hamelinclara on 13 Feb 13 - No Cached
  • This year there were two major factors which contributed to Johnson & Johnson’s number one ranking. It successfully brought to market Abiraterone (Zytiga) - a lyase and steroid synthesis inhibitor for use in the treatment of prostate cancer - and furthermore it was a major riser in the Access to Medicine Index, which is of increasing global importance.”
  • “Roche, which kept its number 3 spot on the Index, saw the first combined launch of a drug and companion diagnostic device, but on the negative side it had to close phase III development of dalcetrapib, a potentially $20bn product. “Sanofi, although rising one place to rank fifth, suffered a massive climbdown with Zaltrap in colorectal cancer launching at a suicidally high price which it continued to defend against increasing criticism. It eventually cut costs to 50 per cent but the damage had been done. “And AstraZeneca is the perfect example of a company which has shown all the signs of panic over the past five years. The stress of an underwhelming pipeline has led it to make bad decisions on top of bad decisions, and although it enjoyed some top line growth by flogging its sales model, the same primary care sales model has led to poor decisions in many areas.”
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