In this case, developed for an introductory genetics class, students meet a woman whose family has a history of colon cancer. Students create a pedigree based on information from the case and discuss what it means to be genetically predisposed to cancer. Using bioinformatics tools from the NCBI database, students identify and examine the mutation in the woman's APC gene that results in genetic predisposition to colon cancer. Finally, they investigate the biological function of the APC protein to understand why this mutation contributes to the development of cancer and determine whether APC is a proto-oncogene, tumor suppressor gene, or genome stability gene.
As benign as it may look up close, the tiny seaweed Caulerpa taxifolia can wreak quite a bit of havoc on coastal ecosystems. This super algae is very adaptable; it also grows fast and spreads easily. Eric Noel Muñoz gives the details of this plant's incredible invasion, shedding light on the risks of introducing invasive species into new ecosystems.
