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Inthis lesson students will enter the world of the genome, learning about humanhistory and evolution by examining information about human, Neanderthal, andchimpanzee DNA. Using web interactives and videosfrom The Human Spark, studentswill be introduced to the ambitious Human Genome Project, learn about thegenetic similarities and differences between human beings and our hominidancestors, explore how specific genes manifest themselves in differentorganisms, and discover how genetic information can help us trace a path ofhuman migration all the way back to our earliest ancestors.

This video excerpt from NOVA examines the dilemma some people face when they are deciding whether to undergo genetic testing. Journalist Catherine Elton describes her decision to refuse a test for BRCA1, a mutation that signals an increased risk of breast and ovarian cancers, despite the history of disease in her family. The video also explains that genetic testing results can help some individuals improve their wellness, prevent the onset of diseases they are at risk for, or lessen the harmfulness of diseases they do contract.

This video excerpt from NOVA examines the promise and realities of developing drugs designed to treat genetic disorders. The video presents the story of one patient, Michael McCarrick, whose lungs were devastated from years of suffering from cystic fibrosis. After researchers identified the gene involved in cystic fibrosis, it took decades to find ways to fortify the faulty protein responsible for the serious illness. While two drugs, including one called Kalydeco, offer a small number of patients hope that they will not have to endure a lung transplant, it may be years and several hundred million more development dollars before effective drugs are available for a wider population.

This video excerpt from NOVA uncovers the genetic mystery that nearly killed Alexis, now 14, and introduces the debate surrounding genetic testing at birth. After diagnosing Alexis and her twin brother Noah with cerebral palsy at a young age, doctors later discovered that the twins shared a rare genetic mutation that led to a condition that mimics cerebral palsy. The twins improved after receiving treatment, but then Alexis took a turn for the worse. Thanks to whole genome sequencing, doctors discovered a second problem linked to the mutation and gave her a different treatment that saved her life.

In this lesson, students explore some of the risks and benefits of gene-based medicine. They look at concerns related to genetic testing (which looks for particular genetic variations) and personal genome sequencing (which sequences the entire genome of an individual). Through videos and discussions, students learn about existing technologies for genetic testing and therapies. They also explore matters such as the emotional consequences of genetic testing, discrimination, and privacy issues. In small groups, students discuss scenarios and then share and analyze related opinions and concerns.

This video segment adapted from NOVA scienceNOW examines the realm of personal DNA testing. It describes the latest tests, which look for single-nucleotide polymorphisms (SNPs). These single-letter differences in DNA sequence make humans unique from one another but may also predispose people to certain diseases. The video also discusses the Personal Genome Project, an extension of the Human Genome Project aimed at determining the root causes of many common diseases. The Personal Genome Project takes into account personal genomics as well as lifestyle information, such as one's living environment, habits, and behaviors.

North Carolina Science Now brings science out of the lab and into the classroom.  This collection of 5-7 minute videos includes related links and discussion questions for teachers and students.

In the end, Darwin came up with an entirely new theory to explain the extraordinary lengths many animals will go to in order to woo a potential mate. He called it sexual selection. Simply put, sexual selection is the evolutionary process that favors adaptations that increase an animal's chances of mating. Darwin identified two kinds. In the first, males compete fiercely with each other for access to females. This kind favors the evolution of secondary sexual characters, such as large size and armaments like horns, that enhance a male's ability to fight. In the second, males compete to win over a female.

This interactive activity adapted from the University of Alberta illustrates how, through a process called fixation, nitrogen flows from the atmosphere, into the soil, through various organisms, and back to the atmosphere in a continuous cycle.

interactive biomes

From single-celled organisms to giant redwoods, Life Science explores all of Earth's life forms. Use interactive, animated activities to identify the living and nonliving components of an ecosystem, design a Venn diagram to compare the migrations of monarch butterflies and red knot shorebirds, and take a virtual field trip to a solar farm. Resources in Life Science gives you a wide range of topics, including the cell cycle, genetic disorders, and bioethics.