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Crohn's Disease and IBD - Genetic "Switches" | Foundation for Biomedical Research - 0 views

fbresearch.org/sease-and-ibd-genetic-switches

chron's ibd inflammatory bowel disease zebrafish animal model animal research Duke uhrf1 TNF

shared by Lottie Peppers on 27 Feb 15 - No Cached

Lottie Peppers on 27 Feb 15

Over a million people in the United States have some form of Inflammatory Bowel Disease or IBD. It can be caused by intestinal bacteria, environment or genetics. One thing is for sure, the lining of the intestines don't work correctly because the cells have been disturbed by one of these things. A common finding in Crohn's and IBD is that a molecule called TNF is elevated, and starts the inflammation process. Researchers still don't know what signals the TNF to go up, but maybe they can turn it off with another molecule.

<div class="cArrow"> </div><div class="cContentInner">Over a million people in the United States have some form of Inflammatory Bowel Disease or IBD. It can be caused by intestinal bacteria, environment or genetics. One thing is for sure, the lining of the intestines don't work correctly because the cells have been disturbed by one of these things. A common finding in Crohn's and IBD is that a molecule called TNF is elevated, and starts the inflammation process. Researchers still don't know what signals the TNF to go up, but maybe they can turn it off with another molecule.</div>

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