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3:35 video Enzymes are the critical ingredient in every organism that make life possible. They are catalysts and drive every chemical reaction that takes place in the human body, enabling our bodies to be built from proteins, carbohydrates, and fats. In this program from VEA we investigate the role of enzymes in detail, offering both theoretical and practical examples.

4:51 video What's tasty, abundant and high in protein? Bugs! Although less common outside the tropics, entomophagy, the practice of eating bugs, was once extremely widespread throughout cultures. You may feel icky about munching on insects, but they feed about 2 billion people each day (Mmm, fried tarantulas). They also hold promise for food security and the environment. Emma Bryce makes a compelling case for dining on bugs.

Bipolar disorder is a common, complex genetic disorder, but the mode of transmission remains to be discovered. Many researchers assume that common genomic variants carry some risk for manifesting the disease. The research community has celebrated the first genome-wide significant associations between common single nucleotide polymorphisms (SNPs) and bipolar disorder. Currently, attempts are under way to translate these findings into clinical practice, genetic counseling, and predictive testing. However, some experts remain cautious. After all, common variants explain only a very small percentage of the genetic risk, and functional consequences of the discovered SNPs are inconclusive. Furthermore, the associated SNPs are not disease specific, and the majority of individuals with a "risk" allele are healthy. On the other hand, population-based genome-wide studies in psychiatric disorders have rediscovered rare structural variants and mutations in genes, which were previously known to cause genetic syndromes and monogenic Mendelian disorders.

Taxonomy is the study of scientific classification, in particular the classification of living organisms according to their natural relationships. Taxonomy's first father was the philosopher Aristotle (384-322 BC), sometimes called the "father of science." It was Aristotle who first introduced the two key concepts of taxonomy as we practice it today: classification of oranisms by type and binomial definition.

Taxonomy, the practice of classifying biodiversity, has a venerable history. Although early natural historians did not recognize that the similarities and differences among organisms were consequences of evolutionary mechanisms, they still sought a means to organize biological diversity.

"Bioethics is the study of ethical, legal, and social issues raised by advances in biology and medicine. Bioethics addresses a range of controversial topics, including privacy and fairness in the use of genetic information, integration of new technologies, such as genetic testing, into medical practice, and the design and conduct of research studies and clinical trials.  "

Data Nuggets are free classroom activities, co-designed by scientists and teachers, designed to bring contemporary research and authentic data into the classroom. Data Nuggets include a connection to the scientist behind the data and the true story of their research. Each activity gives students practice working with 'messy data' and interpreting quantitative information. Students are guided through the entire process of science, including identifying hypotheses and predictions, visualizing and interpreting data, making evidence based claims, and asking their own questions for future research. Because of their simplicity and flexibility, Data Nuggets can be used throughout the school year and across grades K-16, as students grow in their quantitative abilities and gain confidence." Sounds like real science to me!

"Our vision for supporting instructional leaders in their work with teachers to improve science teaching and learning stems from our approach to instructional supervision and science instruction."

The following pages contain a wide range of resources for secondary science teachers to use in their classroom. The majority of these lessons have been created through CPET programs by teachers and graduate students, but also lessons used by CPET during the programs as well as best practices that teachers have contributed to our collection.

inquiryHub high school and middle school curricula are aligned to the Framework and guided by the Next Generation Science Standards (NGSS). Using research-based approaches to teaching science in a deeply digital environment, students contribute resources, observations, data, and analyses to solve larger scientific problems.  inquiryHub curricula are designed to go beyond traditional science content. By focusing on phenomena relevant to students' lives and communities, the coursesprovides opportunities to authentically engage with science and engineering practices.

"What is Ambitious Science Teaching? Great teaching can be learned. This web site provides a vision of ambitious science instruction for elementary, middle school and high school classrooms. Ambitious teaching deliberately aims to support students of all backgrounds to deeply understand science ideas, participate in the activities of the discipline, and solve authentic problems. We feature 4 core sets of teaching practices that support these goals. These core sets make up the Ambitious Science Teaching Framework. The framework has been based on classroom research from the past 30 years-research that has asked, "What kinds of talk, tasks, and tools do students need in order to fully engage in meaningful forms of science learning?""

"inquiryHub is a research practice partnership engaged in research and development of materials, tools, and processes to promote equitable student learning of STEM. inquiryHub Biology is an open access, deeply digital high school biology curriculum designed to support the Next Generation Science Standards.  "

The activity begins with students observing different organisms or phenomena and developing questions based on their observations. They then sort their questions into those that can and cannot be answered using the methods of science. Students practice writing scientific questions, designing experiments to address scientific questions, developing questions that involve cause and effect, and understanding the importance of cause and effect questions in scientific research. At the end of the activity, students determine the research questions being asked from reading journal article titles and parts of a published paper or other reported results. Several possible extension activities are provided for continuing the investigation and research of phenomena.

n. As such, this set of Essential Elements addresses a small number of science standards, representing a breadth, but not depth, of coverage across the entire standards framework. The purpose of the DLM Essential Elements is to build a bridge from the content in the general education science framework to academic expectations for students with the most significant cognitive disabilities. This version of the Essential Elements will provide content for science assessments for at least the next two years. The DLM Science Consortium intends to develop a learning map based on research about how students learn science content and engage in scientific and engineering practices in the next phase of the project. Revisions will be made when the science map is complete, at which time we anticipate the EEs will be aligned to the map with revisions and additions as appropriate.

This "clicker case" tells the story of "Hannah," a baby girl adopted by two loving parents who grows up with an uncontrolled appetite and develops severe early-onset obesity. Students follow Hannah's story as she develops excessive eating early in life, which her health care team is unable to explain. A visit to obesity specialists finally reveals the underlying cause of Hannah's obsession with food: extremely low levels of circulating leptin, a hormone that regulates appetite and body weight. It is further discovered that Hannah's leptin deficiency is due to a mutation in the LEP gene. As the story unfolds, students first work on unit conversions and BMI calculations to practice quantitative skills as well as graph and data interpretation skills. Students then apply their knowledge of DNA transcription, translation, and protein structure to answer questions based on figures from a 2019 study on LEP mutations. The case is best suited for high school and lower-level undergraduate biology courses.

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