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Immune cells in mice with lupus symptoms have overactive metabolisms, so scientists inhibited two metabolic pathways and succeeded in reversing lupus symptoms in mice

Over recent decades, scientists have made various discoveries about DNA methylation and how vital it is to a number of cellular processes such as embryonic development, X-chromosome inactivation, genomic imprinting, gene suppression, carcinogenesis and chromosome stability. Researchers have linked abnormal DNA methylation to several adverse outcomes, including human diseases.