A zebrafish model of a rare genetic disease has revealed an unexpected regulatory pathway for cholesterol absorption and processing.
The findings, reported in the Journal of Molecular Medicine, were "quite surprising and have the potential to teach us about the basic physiology of cholesterol management," said Ela Knapik, M.D., associate professor of Medicine and Cell and Developmental Biology.
Human and animal disease are often caused by viruses or bacteria. Over the past two hundred or so years, vaccines have eradicated some of these diseases. Others have returned to haunt humans with new and ever-mutating strains. Communicable diseases may spread in different ways: through blood, air, feces/urine, food, or water. The World Health Organization (WHO) and the Center for Disease Control (CDC) keep constant watch over the most potentially dangerous diseases and the most likely threats to various world populations.