OpenSciInfo

by Daniel Shiffman. Renders a simple tree-like structure via recursion Branching angle calculated as a function of horizontal mouse location

We are focused on providing tools to our users to ensure that they can add information of interest to structure-based records in ChemSpider. We have introduced DOI-based associations recently allowing users to connect publications of interest to chemical compounds on our database. The process is simple. Find the structure record of interest, use the Add DOI function and Publish. The process is outlined graphically below.

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ChemSpider is a free access service providing a structure centric community for chemists. Providing access to millions of chemical structures and integration to a multitude of other online services ChemSpider is the richest single source of structure-based chemistry information.

bioconductor.org Bioconductor is an open source and open development software project for the analysis and comprehension of genomic data.

Not a few biologists tend to consider wiki as a solution to manage and reorganize data by a community. However, in its basic functionality, wiki lacks a measure to check data consistency and is not suitable for a database. To circumvent this pitfall, installation of page dependency through in-line page searches is necessary. We also introduce two existing approaches that support in-line queries.

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, non-profit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics and funded by the NIH National Center for Research Resources (grant P41-RR01081).

If required, entire databases can be downloaded from our FTP site in a variety of formats, from flat files to MySQL dumps. Please be aware that these files can run to many gigabytes of data. To facilitate storage and download all databases are GNU Zip (gzip, *.gz) compressed. Please note: Ensembl supports downloading of many correlation tables via the highly customisable BioMart data mining tool. You may find exploring this web-based data mining tool easier than extracting information from our database dumps.

BioMart is a query-oriented data management system developed jointly by the Ontario Institute for Cancer Research (OiCR) and the European Bioinformatics Institute (EBI). The system can be used with any type of data and is particularly suited for providing 'data mining' like searches of complex descriptive data. BioMart comes with an 'out of the box' website that can be installed, configured and customised according to user requirements. Further access is provided by graphical and text based applications or programmatically using web services or API written in Perl and Java. BioMart has built-in support for query optimisation and data federation and in addition can be configured to work as a DAS 1.5 Annotation server. The process of converting a data source into BioMart format is fully automated by the tools included in the package. Currently supported RDBMS platforms are MySQL, Oracle and Postgres. BioMart is completely Open Source, licensed under the LGPL, and freely available to anyone without restrictions.

For large amounts of data and more detailed analysis, we recommend you use our publicly-accessible MySQL server, ensembldb.ensembl.org, which you can access as user 'anonymous'. A second server, martdb.ensembl.org provides public access to the BioMart databases.

FindPeaks 3.1: a tool for identifying areas of enrichment from massively parallel short-read sequencing technology

his meeting was about "Making the Web Work for Science and the Impact of e-Science and the Cyberinfrastructure." I provided an overview of how access to information has changed over the past 20 years for me. I talked about the challenges for publishers serving the chemistry community and how their business models are being challenged and how I empathize with the struggle to figure out how to deal with it. I talked about quality and how care must be taken when using information online. We are ALL challenged with errors - whether you consider PubChem, ChemSpider, Wikipedia or any of the other online databases they all have errors - how do you find them? Some of them are obvious and I pointed to obvious examples in the talk. I hoped to educate the attendees in regards to the value of InChI which, while not a perfect fit yet, is a great start to structure-based communication of chemistry. I publicly blessed the efforts of publishers such as the RSC and Nature Publishing group for the efforts they are making to support InChI and improve the quality of document presentation online. I blessed CAS as a treasure trove of information and the gold standard of curated chemistry. We need them all to be successful for the sake of our science. The challenge is how to fit into the ongoing proliferation of free access to information without modifying the business models.

The presentation provides an overview of some of the challenges the publishers face moving forward, how they are responding to it, how InChI is an enabling technology, how quality is important.

These Web Services can be used to create applications on Molecules and their Properties. Details of the Web Services can be found here. If you are new to using these Web Services, please take a few minutes to read the instructions here.

This package contains code for use with Short Read DNA Sequencing technologies, and includes packages for ChIP-Seq, Whole Transcriptome Shotgun Sequencing, Whole Genome Shotgun Sequencing, SNP Detection, Transcript expression and file conversion.

This package of tools encompasses many of the common pieces of software required for the analysis of short read sequences produced by the Second Generation DNA sequencing machines. (eg. Illumina/Solexa sequencers, ABI SOLiD and 454). The focus of this project is on post-alignment analysis, thus the input for this process should be the files produced by sequence aligners such as MAQ, Eland or Exonerate. The output should be provided in several formats, including BED and WIG files which are readable by the UCSC Genome Browser.

To establish a method of measuring the solubility of some compounds in organic solvents. For a justification of this project see here.

Welcome to the Directory of Open Access Journals. This service covers free, full text, quality controlled scientific and scholarly journals. We aim to cover all subjects and languages. There are now 3768 journals in the directory. Currently 1327 journals are searchable at article level. As of today 240018 articles are included in the DOAJ service.

The BioInfoBank Meta Server offers a gateway to well-benchmarked protein structure and function prediction methods. Structural models collected from the prediction servers are assessed using the powerful 3D-jury consensus approach.

With the following three steps, you can set up a Disco cluster in the Amazon's Elastic Computing Cloud. This will cost you a few dollars (or more, depending on your needs) but requires no resources on your side besides a single machine that you use to setup the cluster. In this setup Disco master and nodes run on EC2. Your Disco client can run either on the master node on EC2 or on a local machine.