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The Science and Technology Centers (STC): Integrative Partnerships program supports exceptionally innovative, complex research and education projects that require large-scale, long-term awards. STCs focus on creating new scientific paradigms, establishing entirely new scientific disciplines and developing transformative technologies which have the potential for broad scientific or societal impact. STCs conduct world-class research through partnerships among institutions of higher education, national laboratories, industrial organizations, other public or private entities, and via international collaborations, as appropriate. They provide a means to undertake potentially groundbreaking investigations at the interfaces of disciplines and/or highly innovative approaches within disciplines. STCs may involve any area of science and engineering that NSF supports. STC investments support the NSF vision of creating and exploiting new concepts in science and engineering and providing global leadership in research and education.

This Program Announcement/Funding Opportunity is focused on specific research topics of psychological health and well-being of military personnel and their families as outlined in section B. Investigators must demonstrate logical reasoning and a sound scientific rationale established through a critical review and analysis of the literature for the proposal to be competitive. Research projects should include a well-formulated, testable hypothesis based on a strong scientific rationale. This award mechanism is focused on applied research, defined as research that refines concepts and ideas into potential solutions to military health and performance problems with a view toward evaluating technical feasibility; includes studies and investigations leading to candidate solutions in preparation for initial human testing. This award mechanism will also support advanced technology development which is defined as research for the development of candidate solutions and components of early prototype systems for test and evaluation. Promising drug and vaccine candidates and medical devices and technologies are selected for initial safety and efficacy testing in small scale human clinical trials. Applications may include phase I or early phase II clinical trials, but not late phase II large-scale effectiveness clinical trials or advanced development of products and capabilities.

The Society of Pediatric Psychology (SPP) is pleased to announce its Targeted Research Grant program. This annual program was established to fund research projects that will contribute to priority and emerging areas in the field of pediatric psychology, and that will allow investigators to collect pilot data to aid in securing additional major grant funding. For the 2013 award cycle, the priority areas identified are: Technology ( eHealth interventions and information and communication technologies)Health care cost-offset researchPrimary care-focused practice or interventionsStudies of novel measurement/assessment strategies (e.g., validation of new questionnaires focused on patient-reported outcomes)Another novel or emerging research area in the field of pediatric psychology. Applicant must demonstrate or document why this area is novel or emerging. SPP will award up to two grants in the amount of $20,000 each to cover one year of funding to those research proposals demonstrating the greatest merit and potential for success. Although priority will be given to young investigators (within seven years of PhD), investigators at any stage of career are encouraged to apply for this funding. For example, a mid-career researcher who is moving into a new emerging research area would be eligible to apply. Only sole principal investigator (PI) applications will be accepted. Application Deadline: Oct. 1

DARPA Defense Sciences Office (DSO) wants to identify and pursue high-risk, high-payoff research initiatives across a broad spectrum of science and engineering disciplines and to transform these initiatives into important, radically new, game-changing technologies for U.S. national security. The current overarching office themes include accelerating scientific discovery, exploring fundamental limits, and expecting the unexpected. In support of this mission, the DSO Office-wide BAA invites proposers to submit innovative basic or applied research concepts in one or more of the following technical areas: Mathematics, Modeling and Design; Physical Systems; Human-Machine Systems; and Social Systems. Each of these areas is described below and includes a list of example research topics that highlight several (but not all) potential areas of interest. Proposals must investigate innovative approaches that enable revolutionary advances. DSO is explicitly not interested in approaches or technologies that primarily result in evolutionary improvements to the existing state of practice.

The FY15 JPC-8/CRMRP ERI is intended to support Phase I, II, or pivotal clinical trial phase development projects focused on extremity regeneration. The focus is on bone and soft tissue reconstruction, limb and tissue salvage technologies, and regenerative medicine technologies for the treatment of trauma-induced damage.

The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is aimed at revolutionizing neuroscience through development and application of innovative technologies to map neural circuits, monitor and modulate their activity, and understand how they contribute to thoughts, sensations, emotions and behavior. NIH has issued a variety of Funding Opportunity Announcements (FOAs) that will support projects that apply technologies to understand neural circuit function in the context of specific circuits, resulting in a diverse portfolio of research into the fundamental biology of nervous system function. The purpose of this announcement is to notify the research community that NIH welcomes BRAIN Initiative applications targeting central nervous system nociceptive and pain circuits, as appropriate to the goals and requirements of specific BRAIN Initiative FOAs. Pain conditions represent an important public health problem and NIH continues to support research into pain pathologies through normal Institute and Center appropriations. However, pain and nociception are also components of normal nervous system function, and the BRAIN Initiative is committed to understanding pain circuits along with brain circuits underlying other sensory, motor, cognitive and emotional functions. It is expected that the unique opportunities of the BRAIN Initiative will enable production of detailed maps of pain circuits, and the adoption of powerful new tools for monitoring and modulating pain circuit activity, leading to significant advances in the understanding of pain and nociception. For a list of past and open BRAIN Initiative FOAs, see https://braininitiative.nih.gov/funding/.

With this solicitation, NIJ seeks applications for funding of multidisciplinary research projects addressing three topics: 1) The impact of fatigue and stress on officer performance. 2) Enhancing strategies for officer interaction with mentally ill individuals. 3) Advancing Resiliency for the Forensic Workforce- Understanding the Impact and Management of Stress, Burnout, and Vicarious Trauma. This solicitation supports the U.S. Department of Justice’s priority of protecting officers and other public safety personnel. This solicitation also supports the following five objectives of the NIJ Safety, Health, and Wellness Strategic Research Plan 2016-2021 (August 2016): 1) Objective I.2: Support development, and promote strategies, policies, practices, and technologies that enhance the safety of criminal justice personnel. 2) Objective I.4: Develop policies, strategies, and technologies to promote safety in criminal justice interactions with the public. 3) Objective II.1: Promote research to improve the physical and mental health of individuals working in the criminal justice system. 4) Objective II.2: Study both trauma and suicide among criminal justice employees. 5) Objective II.4: Promote science-based tools and strategies to monitor physical and mental health.

The purpose of this program is to demonstrate how telehealth programs and networks can improve access to health care services, particularly substance abuse treatment services, in rural, frontier, and underserved communities. The range and use of telehealth services have expanded over the past decades, along with the role of technology in improving and coordinating care. Telehealth has proven capabilities to reduce travel time, increase access to specialty care, and improve patient safety, quality of care, and provider support. Traditional models of telehealth involve care delivered to the patient at a series of originating (or spoke) sites from a specialist working at a distant (or hub) site. Telehealth is a promising tool for providing substance abuse treatment services and support to rural populations. Communities that lack sufficient substance abuse treatment and other behavioral health professionals can utilize telehealth technologies to increase access to care.

The Office of Naval Research (ONR) is interested in receiving proposals for its Young Investigator Program (YIP). ONR's Young Investigator Program (YIP) seeks to identify and support academic scientists and engineers who are in their first or second full-time tenure-track or tenure-track-equivalent academic appointment, have begun their first appointment on or after 31 December 2012, and who show exceptional promise for doing creative research. The objectives of this program are to attract outstanding faculty members of Institutions of Higher Education (hereafter also called "universities") to the Department of the Navy's Science and Technology (S&T) research program, to support their research, and to encourage their teaching and research careers. Proposals addressing research areas (as described in the ONR Science and Technology Department section of ONR's website at www.onr.navy.mil) which are of interest to ONR program officers will be considered. Contact information for each division (a subgroup of an S&T Department) is also listed within the S&T section of the website

The purpose of this Funding Opportunity Announcement (FOA) is to: identify new, information technology (IT)-enabled delivery models that support systematic screening and treatment of depression in cancer patients; test the feasibility of implementing these new delivery models in a variety of oncology practice settings, especially those serving under-served populations; and test the usability and potential effectiveness of the IT-specific components of these new delivery models. Also listed under R01

The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) InitiativeSM is aimed at revolutionizing our understanding of the human brain. By accelerating the development and application of innovative technologies, researchers will be able to produce a new dynamic picture of the brain that, for the first time, will show how individual cells and complex neural circuits interact in both time and space. It is expected that the application of these new tools and technologies will ultimately lead to new ways to treat, cure, and even prevent brain disorders.

 Cutting-edge research in the biomedical, behavioral, clinical sciences and technologies requires new ideas, techniques, and points of view. Such ideas may differ substantially from current thinking or practice. The NIBIB seeks to foster these new scientific bioengineering and imaging ideas, model systems, tools, agents, targets, and technologies through the Exploratory/Developmental Research Grant Program.  More detail on our program areas can be found at https://www.nibib.nih.gov/research-funding.

The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is aimed at revolutionizing our understanding of the human brain. By accelerating the development and application of innovative technologies, researchers will be able to produce a new dynamic picture of the brain that, for the first time, will show how individual cells and complex neural circuits interact in both time and space. It is expected that the application of these new tools and technologies will ultimately lead to new ways to treat and prevent brain disorders.

The purpose of this funding opportunity announcement (FOA) is to stimulate clinical research focused on biobehavioral or technological interventions to attenuate cognitive decline in individuals with dementia (such as Alzheimer's disease, Lewy body dementia, vascular dementia), mild cognitive impairment (MCI), or disease- or age-related cognitive decline. There is particular interest in interventions that can be implemented in community settings by the affected individual, informal caregivers, or others in the community. Research to inform the development of such interventions is also of interest, as well as research examining underlying mechanisms and biomarkers associated with response to interventions. It is anticipated that the results of this research will help affected individuals maintain independence and quality of life, improve their ability to perform activities of daily living (ADLs) and instrumental activities of daily living (IADLs), and additionally help to reduce stress, burden, and other poor outcomes in their caregivers.   

The purpose of this funding opportunity announcement (FOA) is to stimulate clinical research focused on biobehavioral or technological interventions to attenuate cognitive decline in individuals with dementia (such as Alzheimers disease, Lewy body dementia, vascular dementia), mild cognitive impairment (MCI), or disease- or age-related cognitive decline. There is particular interest in interventions that can be implemented in community settings by the affected individual, informal caregivers, or others in the community. Research to inform the development of such interventions is also of interest, as well as research examining underlying mechanisms and biomarkers associated with response to interventions. It is anticipated that the results of this research will help affected individuals maintain independence and quality of life, improve their ability to perform activities of daily living (ADLs) and instrumental activities of daily living (IADLs), and additionally help to reduce stress, burden, and other poor outcomes in their caregivers.

The Substance Abuse and Mental Health Services Administration (SAMHSA), Center for Mental Health Services (CMHS) is accepting applications for fiscal year (FY) 2018 Mental Health Technology Transfer Center Cooperative Agreements (Short Title: MHTTC). The purpose of this program is to establish one MHTTC National Coordinating Center, ten (10) MHTTC Regional Centers, one MHTTC Tribal Affairs Center, and one MHTTC Hispanic and Latino Center to develop and maintain a collaborative network to support resource development and dissemination, training and technical assistance, and workforce development to the field and CMHS grant recipients. It is expected that MHTTC Cooperative Agreements will coordinate and manage CMHS's national efforts to ensure that high-quality, effective mental health disorder treatment and recovery support services, and evidence-based practices are available for all individuals with mental disorders including, in particular, those with serious mental illness. Years of research and knowledge of evidence-based practices related to mental disorders show that well-designed prevention, treatment, and recovery support efforts are effective and can have multiple benefits for individuals with mental health disorders, including serious mental illness. It is SAMHSA's intent to ensure that the public has the resources it needs to be successful in treating these conditions. The MHTTCs will work with organizations and treatment practitioners involved in the delivery of mental health services to strengthen their capacity to deliver effective, evidence-based practices to individuals, including the full continuum of services spanning mental illness prevention, treatment, and recovery support.

The Ohio Opioid Technology Challenge is a prize competition seeking innovative solutions to reduce morbidity and mortality associated with opioid use and addiction by addressing prevention, treatment, and overdose response and avoidance. This will be a multi-phase competition with escalating prize amounts associated with progressive levels of solution development. Each phase of the competition will be associated with highly visible events to showcase ideas, announce awards and details of the next phase of the competition, and generally provide a public forum for the discussion of the opioid crisis in Ohio.  The Ohio Development Services Agency is seeking an experienced Competition Manager for this program. 

The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate tools and resources to facilitate the detailed analysis of brain microconnectivity. Novel and augmented techniques are sought that will ultimately be broadly accessible to the neuroscience community for the interrogation of microconnectivity in healthy and diseased brains of model organisms and humans. Development of technologies that will significantly drive down the cost of connectomics would enable routine mapping of the microconnectivity on the same individuals that have been analyzed physiologically, or to compare normal and pathological tissues in substantial numbers of multiple individuals to assess variability. Advancements in both electron microscopy (EM) and super resolution light microscopic approaches are sought. Applications that propose to develop approaches that break through existing technical barriers to substantially improve current capabilities are highly encouraged. Proof-of-principle demonstrations and/or reference datasets enabling future development are welcome, as are improved approaches for automated segmentation and analysis strategies of neuronal structures in EM images.

The purpose of this Funding Opportunity Announcement [FOA] submitted through the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to stimulate the development and validation of novel tools and analytical methods to target, identify and characterize non-neuronal cells in the brain. This FOA complements previous and ongoing cell-census and tool development efforts initiated under BRAIN, RFA-MH-14-215 and RFA-MH-14-216, that have focused almost exclusively on neuronal cells. The cutting-edge tools and methods developed under this opportunity should focus specifically on providing improved points of entry into non-neuronal cell-types (glial and vascular) to enable their inventory and characterization within the CNS and help define how these cells interact among each other and with neuronal cells to impact functional circuitries. Plans for validating the utility of the tool/technology/method and demonstrating its advantage over currently available approaches will be an essential feature of a successful application. Tools that can be used in several species or model organisms rather than in a single species are especially desirable.

The purpose of this Funding Opportunity Announcement (FOA) is to support a consortium of collaborative projects, with a minimum of two sites, that propose to use cutting edge technologies to generate and analyze whole genome sequencing (WGS) data from either case control or family samples in order to elucidate the full genetic architecture underlying susceptibility to severe mental disorders. Insights into the genetic architecture underlying susceptibility to severe mental disorders will be achieved through implementation of state of the art WGS assays and innovative/novel statistical methods.