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The Mechanics of Materials program supports fundamental research on the behavior of solid materials and respective devices under external actions.?? A diverse and interdisciplinary spectrum of research is supported with emphasis placed on fundamental understanding that i) advances theory, experimental, and/or computational methods in Mechanics of Materials, and/or ii) uses contemporary Mechanics of Materials methods to address modern challenges in material and device mechanics and physics. Proposed research can focus on existing or emerging material systems across time and length scales. Intellectual merit typically includes advances in fundamental understanding of deformation, fracture, fatigue, and contact through constitutive modeling, multiscale and multiphysics analysis, computational methods, or experimental techniques.??Recent interests comprise, but are not limited to:?? contemporary materials including multiphase materials and material systems, soft materials, active materials, low-dimensional materials, phononic/elastic metamaterials, friction, wear;??multiphysics methods, mechanics at the nano, meso and microscale and multiscale integration thereof, as well as approaches incorporating fundamental understanding of physics and chemistry into the continuum-level understanding of the response characteristics of materials and material systems.

The Mechanics of Materials and Structures program supports fundamental research in mechanics as related to the behavior of deformable solid materials and respective structures under internal and external actions. A diverse and interdisciplinary spectrum of research is supported with emphasis on research that leads to advances in i) theory, experimental, and/or computational methods in mechanics, and/or ii) uses contemporary mechanics methods to address modern challenges in materials and structures. Proposed research can focus on existing or emerging materials and structural systems, across time and length scales. Proposals related to material response are welcome, and would propose, but not limited to, advances in fundamental understanding of deformation, fracture, fatigue, as well as on contact and friction through constitutive modeling, multi-scale (spatial or temporal) and multi-physics analysis, computational methods, or experimental techniques. Proposals that relate to structural response are welcome and would propose, but not limited to, advances in the understanding of nonlinear deformation, instability and collapse in the context of large deformation, wave propagation, multi-scale (spatial or temporal) and multi-physics analysis, computational methods, or experimental techniques. Proposals at the intersection or considerate of the integration of material and structure (such as, but not limited to, metamaterials, hierarchical, microarchitectured and low-dimensional materials) are especially welcome. Of particular interest are research questions that address the integration and combination of geometry, topology of material distributions, lengthscales and deformation/failure mechanics. Within this context, the challenge of the notion of what constitutes a ??material?? or a ??structure?? is expected to lead to unique opportunities in terms of analysis and experimentation of novel response characteristics. While the research results should contribute to ultimatel

The purpose of this Funding Opportunity Announcement (FOA) is to invite exploratory/developmental research grant (R21) applications for the development of innovative methods and algorithms in biomedical computing, informatics, and data science addressing priority needs across the cancer research continuum, including cancer biology, cancer treatment and diagnosis, cancer prevention, cancer control and epidemiology, and/or cancer health disparities. As a component of the NCI's Informatics Technology for Cancer Research (ITCR) Initiative, this FOA encourages applications focused on the development of novel computational, mathematical, and statistical algorithms and methods that can considerably improve acquisition, management, analysis, and dissemination of relevant data and/or knowledge. The central mission of ITCR is to promote research-driven informatics technology across the development lifecycle to address priority needs in cancer research. In order to be successful, the proposed informatics method or algorithm must have a clear rationale on why it is novel and how it will benefit the cancer research field.

 The methods proposed for validation must be used to identify and quantify chemical constituents (active or marker chemical compounds, adulterants, contaminants, or metabolites thereof) in experimental reagents, raw materials, and/or clinical specimens (for example urine or plasma samples). Methods must have been developed or utilized in fulfillment of the active parent grants specific aims. Candidate constituents for quantitative method validation studies may include (but are not limited to):phytochemicals; nutrients; and potentially deleterious substances such as pesticides and mycotoxins.

The MoM program supports fundamental research in interdisciplinary solid mechanics.  Emphasis is placed on fundamental understanding that i) advances theory, experimental, and/or computational methods in MoM, and/or ii) uses contemporary MoM methods to address modern challenges in material and device mechanics and physics. Proposed research can focus on existing or emerging material systems across time and length scales; especially of interest are contemporary materials including complex solids, phononic/elastic metamaterials, soft materials, and active materials.  Research is welcome in emerging areas of multiscale methods, nanomechanics, manufacturing mechanics, and areas that incorporate fundamental understanding of physics and chemistry into the continuum-level understanding of solids.

Ninesigma's client is a global supplier of high performance materials for a variety of high temperature applications. The ability to functionalise graphite flakes (plus powder and expanded graphite conformations) is important to improve the variety of product formulations currently available. The high hydrophobic nature of graphite materials causes issues in using certain green functional methods. The current methodology involves using different acids which are hazardous and only yields 7-8% of Oxygen or metals on the graphite flakes. Any proposed solutions must be able to provide variable yield functionalisation of hydroxyl and acid groups with the potential to expand to other functional groups listed. The client is open to all solutions from academia and from industry, as long as a clear understanding of the method and requirements for up-scaling are detailed.

Ninesigma's client is a global supplier of high performance materials for a variety of high temperature applications. The ability to functionalise graphite flakes (plus powder and expanded graphite conformations) is important to improve the variety of product formulations currently available. The high hydrophobic nature of graphite materials causes issues in using certain green functional methods. The current methodology involves using different acids which are hazardous and only yields 7-8% of Oxygen or metals on the graphite flakes. Any proposed solutions must be able to provide variable yield functionalisation of hydroxyl and acid groups with the potential to expand to other functional groups listed. The client is open to all solutions from academia and from industry, as long as a clear understanding of the method and requirements for up-scaling are detailed.

NIJ seeks proposals for basic or applied research and development projects that will: (1) increase the body of knowledge to guide and inform forensic science policy and practice or (2) lead to the production of useful materials, devices, systems, or methods that have the potential for forensic application. The intent of this program is to direct the findings of basic scientific research, research and development in broader scientific fields applicable to forensic science, and ongoing forensic science research toward the development of highly discriminating, accurate, reliable, cost-effective, and rapid methods for the identification, analysis, and interpretation of physical evidence for criminal justice purposes.

NineSigma, representing a major building materials manufacturer, invites proposals for methods, materials, or novel approaches to re-inventing weather protection for residential buildings. The weather barrier may be directly exposed or behind a decorative façade, and should be able to withstand thermal, moisture, and UV environments for at least 10 years. Solutions that do not need a decorative façade, that provide lower installed/labor cost versus current solutions, or are cradle-to-cradle approaches are strongly preferred. Solutions that impact vapor barrier, roofing, or sheathing applications are also strongly preferred. The partner is open to a wide range of potential solutions (e.g., replacement with alternative substances, new material architectures, novel processing methods) that can achieve this objective.

Naval Surface Warfare Center (NSWC) Crane and the Office of the Undersecretary of Defense for Research and Engineering (OUSD(R&E))'s Joint Hypersonic Transition Office (JHTO) are interested in receiving research proposals in the following areas. Each will have a Period of Performance (PoP) of 12 months. a. Systems-level design of high-temperature composite materials and structures research utilization of fiber architectures and matrix compositions b. Novel position, navigation, and timing and adaptive flight controls c. Design-oriented models to optimize scramjet and multi-mode engines d. Simulation Methods for the Rapid Prediction of Hypersonic Environments e. Addressing the flow path processes that occur in rectangular or curved inlets and isolators including the destabilization that may occur due to junction flows or off-nominal flight conditions f. The development of methods and models including validation experiments and instrumentation to provide high quality data on multiphase blast properties and structural responses to structures g. Improving the understanding of rotating detonation rocket engine (RDRE) physics and developing design solutions for their inherent technical challenges h. Hypersonic Workforce Curricula Development

Growing Convergence Research (GCR) at the National Science Foundation was identified as one of 10 Big Ideas. Convergence research is a means for solving vexing research problems, in particular, complex problems focusing on societal needs. It entails integrating knowledge, methods, and expertise from different disciplines and forming novel frameworks to catalyze scientific discovery and innovation. GCR identifies Convergence Research as having two primary characteristics: Research driven by a specific and compelling problem. Convergence Research is generally inspired by the need to address a specific challenge or opportunity, whether it arises from deep scientific questions or pressing societal needs. Deep integration across disciplines. As experts from different disciplines pursue common research challenges, their knowledge, theories, methods, data, research communities and languages become increasingly intermingled or integrated. New frameworks, paradigms or even disciplines can form sustained interactions across multiple communities. A distinct characteristic of convergence research, in contrast to other forms of multidisciplinary research, is that from the inception, the convergence paradigm intentionally brings together intellectually diverse researchers and stakeholders to frame the research questions, develop effective ways of communicating across disciplines and sectors, adopt common frameworks for their solution, and, when appropriate, develop a new scientific vocabulary. Research teams practicing convergence aim at developing sustainable relationships that may not only create solutions to the problem that engendered the collaboration, but also develop novel ways of framing related research questions and open new research vistas.

This FOA invites applications for the Microphysiological Systems (MPS) for Disease Modeling and Efficacy Testing Program to develop highly reproducible and translatable in vitro models for preclinical efficacy studies through discovery and validation of translatable biomarkers, development of standardized methods for preclinical efficacy testing and definitive efficacy testing of candidate therapeutics using best practices and rigorous study design. An essential feature will be a multidisciplinary approach that brings together experts in bioengineering, microfluidics, material science, "omic" sciences, computational biology, disease biology, pathology, electrophysiology, pharmacology, biostatistics and clinical science.

This FOA invites applications for the Microphysiological Systems (MPS) for Disease Modeling and Efficacy Testing Program to develop highly reproducible and translatable in vitro models for preclinical efficacy studies through discovery and validation of translatable biomarkers, development of standardized methods for preclinical efficacy testing and definitive efficacy testing of candidate therapeutics using best practices and rigorous study design. An essential feature will be a multidisciplinary approach that brings together experts in bioengineering, microfluidics, material science, "omic" sciences, computational biology, disease biology, pathology, electrophysiology, pharmacology, biostatistics and clinical science.

The Environmental Health and Safety of Nanotechnology (Nano EHS) program provides support to examine and mitigate the environmental effects of nanotechnologies.  Fundamental research is sought to understand, evaluate, and lessen the impact of nanotechnology on the environment and biological systems.  The program emphasizes engineering principles underlying the environmental health and safety impacts of nanotechnology.  Innovative methods related to clean nanomaterials production processes, waste reduction, recycling, and industrial ecology of nanotechnology are also of interest.

The Environmental Health and Safety of Nanotechnology (Nano EHS) program provides support to examine and mitigate the environmental effects of nanotechnologies.  Fundamental research is sought to understand, evaluate, and lessen the impact of nanotechnology on the environment and biological systems.  The program emphasizes engineering principles underlying the environmental health and safety impacts of nanotechnology.  Innovative methods related to clean nanomaterials production processes, waste reduction, recycling, and industrial ecology of nanotechnology are also of interest.  

The Land-Cover/Land-Use Change (LCLUC) program is developing interdisciplinary research combining aspects of physical, social, and economic sciences, with a high level of societal relevance, using remote sensing tools, methods, and data. One of its stated goals is to develop the capability for periodic satellite-based inventories of land-cover and monitoring and characterizing land-cover and land-use change.

The MPM program supports fundamental, hypothesis-driven research on the interrelationship of materials processing, structure, properties, performance and process control. Analytical, experimental, and numerical studies are supported, including novel processing methods for any materials system (metals, polymers, ceramics, hybrids, composites, etc.). Proposed research should include the consideration of cost, performance, and feasibility of scale-up, as appropriate. Research that address multi-scale and/or multi-functional materials systems is encouraged as is research in support of environmentally-benign manufacturing. Collaborative proposals with industry (GOALI) are encouraged. Research on micro-scale (and larger) processes is funded by the MPM program; research on processing at the submicron or nano scale is funded by the Nanomanufacturing (NM) program. Research on solid freeform fabrication processes is funded by the Manufacturing Machines and Equipment (MME) program, as are material removal process proposals such as cutting or grinding. Proposals that focus on research leading to new paradigms of material systems design should consider the Design of Engineering Material Systems (DEMS) program. Proposals that primarily focus on fundamental material composition-structure-property studies, where neither processing nor manufacturing plays a significant role in the proposed work, should be submitted to the Materials and Surface Engineering (MSE) program or to the appropriate program in the DMR division.Investigators wishing to serve on a proposal review panel should email the Program Director with a short biographical sketch, a list of areas of expertise and/or a link to their home page. REU/RET supplement requests should be submitted by March 31 each year.

The SD2 program aims to develop data-driven methods to accelerate scientific discovery and robust design in domains that lack complete models. Engineers regularly use high-fidelity simulations to create robust designs in complex domains such as aeronautics, automobiles, and integrated circuits. In contrast, robust design remains elusive in domains such as synthetic biology, neuro-computation, cyber, and polymer chemistry due to the lack of high-fidelity models. SD2 will develop tools to enable robust design despite the lack of complete scientific models.

The purpose of NIDILRR's DRRPs, which are funded through the Disability and Rehabilitation Research Projects and Centers Program, is to improve the effectiveness of services authorized under the Rehabilitation Act by developing methods, procedures, and rehabilitation technologies that advance a wide range of independent living, employment, and health outcomes for individuals with disabilities, especially individuals with the most significant disabilities.

The Chemical and Biological Separations (CBS) program supports fundamental research on novel methods and materials for separation processes.  These processes are central to the chemical, biochemical, materials, energy, and pharmaceutical industries.  A fundamental understanding of the interfacial, transport, and thermodynamic behavior of multiphase chemical systems as well as quantitative descriptions of processing characteristics in the process-oriented industries is critical for efficient resource management and effective environmental protection.  The program encourages proposals that address emerging research areas and technologies, have a high degree of interdisciplinary thought coupled with knowledge creation, and integrate education and research.

MGI recognizes the importance of materials science to the well-being and advancement of society and aims to "deploy advanced materials at least twice as fast as possible today, at a fraction of the cost." DMREF integrates materials discovery, development, property optimization, and systems design and optimization, with each employing a toolset to be developed within a materials innovation infrastructure. The toolset will synergistically integrate advanced computational methods and visual analytics with data-enabled scientific discovery and innovative experimental techniques to revolutionize our approach to materials science and engineering.

This program supports theoretical and computational materials research and education in the topical areas represented in DMR programs, including condensed matter physics, polymers, solid-state and materials chemistry, metals and nanostructures, electronic and photonic materials, ceramics, and biomaterials. The program supports fundamental research that advances conceptual, analytical, and computational techniques for materials research. A broad spectrum of research is supported using electronic structure methods, many-body theory, statistical mechanics, and Monte Carlo and molecular dynamics simulations, along with other techniques, many involving advanced scientific computing. Emphasis is on approaches that begin at the smallest appropriate length scale, such as electronic, atomic, molecular, nano-, micro-, and mesoscale, required to yield fundamental insight into material properties, processes, and behavior and to reveal new materials phenomena. Areas of recent interest include, but are not limited to: strongly correlated electron systems; low-dimensional systems; nonequilibrium phenomena, including pattern formation, microstructural evolution, and fracture; high-temperature superconductivity; nanostructured materials and mesoscale phenomena; quantum coherence and its control; and soft condensed matter, including systems of biological interest.