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The purpose of this funding opportunity announcement (FOA) is to advance the field of population dynamics research by increasing research impact, innovation, and productivity; develop junior scientists; and maximize the efficiency of research support.

The purpose of this funding opportunity announcement (FOA), issued by the Office of the Director (OD), National Institutes of Health (NIH), is to invite applications from entities/institutions in Institutional Development Award (IDeA)-eligible States to participate in the Environmental Influences on Child Health Outcomes (ECHO) IDeA States Pediatric Clinical Trials Network (ISPCTN) as the Data Coordination and Operations Center (DCOC). The DCOC will support the Clinical Sites of the ISPCTN to: --Conduct multicenter clinical trials research, assuring the participation of children living in rural or underserved communities located in Institutional Development Award (IDeA) states. --Build pediatric research capacity for IDeA states to support the conduct of clinical trials of relevance to rural or underserved children in IDeA states.

 This funding opportunity announcement (FOA), issued by the Office of the Director (OD), National Institutes of Health (NIH), invites applications from entities/institutions in Institutional Development Award (IDeA)-eligible States to participate as the Data Coordination and Operations Center (DCOC) in the Environmental Influences on Child Health Outcomes (ECHO) IDeA States Pediatric Clinical Trials Network (ISPCTN). The DCOC will support the Clinical Sites of the ISPCTN to conduct multicenter clinical trials research, assuring the participation of children living in rural or underserved communities located in IDeA states, and build pediatric research capacity for IDeA states to support the conduct of clinical trials of relevance to rural or underserved children in IDeA states. The DCOC and the Clinical Sites, together, will form the ISPCTN.    The ISPCTN is the intervention part of the ECHO program and supports its overall mission: to enhance the health of children for generations to come. The award will support clinical trial pediatric research in the 5 focus areas of the ECHO program: pre-, peri-, and postnatal outcomes; obesity; upper and lower airways; neurodevelopment; and positive health.