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The Human Cell Atlas (HCA) is a global effort to create a reference map of all cell types in the human body. The Chan Zuckerberg Initiative and the Helmsley Charitable Trust are pleased to announce continued support for the Human Cell Atlas by collaborating on two new funding mechanisms that the community can access through a single application portal. The Chan Zuckerberg Initiative seeks to continue the work of the HCA community with a focus on interdisciplinary work and collaboration through the formation of 3 year Seed Networks. The Helmsley Charitable Trust welcomes applications that will construct a detailed atlas of the human gut. Project Specifications This Request for Applications (RFA) seeks to support the continued growth of nascent projects and to incubate new networks. The Seed Networks should generate new tools, open source analysis methods, and significant contributions of diverse data types to the Human Cell Atlas Data Coordination Platform. Applications should have a primary focus on the healthy tissues that will contribute to a reference atlas. Seed Networks Seed Networks should consist of at least three principal investigators, including at least one computational biologist or software engineer, together with additional computational biologists, engineers, experimental biologists, and/or physicians. CZI Seed Networks aim to support foundational tools and resources for the HCA and will not require a gut component in the application. CZI Seed Network Grants have four overarching scientific goals: - Build and support networks of collaborating scientists and engineers; - Contribution of high-quality data to v1.0 of the HCA; - Development of new technologies and benchmark data sets, particularly those anchored in spatial as well as molecular information; - Support of computational biology within the Human Cell Atlas community.

The HFSP supports novel, innovative and interdisciplinary basic research focused on the complex mechanisms of living organisms; topics range from molecular and cellular approaches to systems and cognitive neuroscience and the interactions between organisms. A clear emphasis is placed on novel collaborations that bring biologists together with scientists from fields such as physics, mathematics, chemistry, computer science and engineering to focus on problems at the frontier of the life sciences.