The purpose of this Funding Opportunity Announcement (FOA) is to invite applications for research projects designed to use sound and innovative strategies to solve specific problems and paradoxes in childhood cancer research identified by the National Cancer Institute (NCI) as the NCIs Pediatric Provocative Questions (Pediatric PQs). These problems and paradoxes framed as questions are not intended to represent the full range of NCI's priorities in childhood cancer research. Rather, they are meant to challenge cancer researchers to think about and elucidate specific problems in key areas of pediatric cancer research that are deemed important but have not received sufficient attention.

The purpose of this Funding Opportunity Announcement (FOA) is to invite applications for research projects designed to use sound and innovative strategies to solve specific problems and paradoxes in childhood cancer research identified by the National Cancer Institute (NCI) as the NCIs Pediatric Provocative Questions (Pediatric PQs). These problems and paradoxes framed as questions are not intended to represent the full range of NCI's priorities in childhood cancer research. Rather, they are meant to challenge cancer researchers to think about and elucidate specific problems in key areas of pediatric cancer research that are deemed important but have not received sufficient attention.

The purpose of this funding opportunity is to establish a program of research to advance the understanding, prevention and treatment of pediatric multiple organ dysfunction syndrome (MODS). Given the prevalence and associated morbidity and mortality of MODS in children, the current lack of understanding underscores the need for more exploratory research. Possible topics of study include, but are not limited to, the epidemiology, pathophysiology, monitoring, and treatment of MODS. Studies that assess specific etiologies associated with MODS including, but not limited to, sepsis, trauma, acute respiratory distress syndrome, inborn errors of metabolism, burns, cancer, transplantation and congenital heart disease are encouraged. Applications may include any appropriate study design ranging from basic science animal models through small prospective randomized controlled trials. The intent of this R21 funding initiative is to encourage exploratory and developmental research projects by providing support for the early and conceptual stages of research projects addressing these topics. These studies may incur considerable research risk in efforts to make important breakthroughs in the understanding, prevention and treatment of MODS in children. Projects of limited cost or scope that use widely accepted approaches and methods within well-established fields are better suited for the R03 small grant activity code. It is hoped that the results of this exploratory research will translate into improved clinical outcomes for children with, and at risk for MODS.

Today, more than six million children around the world die needlessly before reaching the age of five. Some of the leading causes of child death include preterm birth complications, pneumonia, intrapartum-related complications, diarrhea, and sepsis/ meningitis. Applicants from all walks of life, and from all over the world, are invited to submit a proposal outlining how they plan to save the lives of children under the age of five who would otherwise die from a treatable and preventable cause. All proposals must include a science-based approach to measuring and evaluating the impact of the lives saved. One winner will be awarded $250,000 to directly execute the proposed project.

Non-clinical studies in juvenile animal models have shown that exposure to some anesthetics and sedatives is associated with neurodegenerative changes in the central nervous system, as well as memory and learning deficits. Anesthetic agents that have been specifically implicated are NMDA receptor antagonists, such as ketamine, and GABA agonists, such as sevoflurane. The anesthesia community and the FDA acknowledge that there are insufficient human data to either support or refute the clinical relevance of these findings for pediatric patients. Therefore, numerous non-clinical and clinical studies are needed to assess the effect of anesthetics and sedatives on the developing human brain, including long-term studies in neonates and young children.  However, the planning and performance of the numerous studies needed to address the aforementioned issues will involve enormous challenges in terms of design, assurance of validity and reliability of the outcome measures, and ethical considerations. It is unlikely that any one entity will possess the necessary expertise and resources to accomplish all the work needed to address the issues in an expeditious manner.  FDA seeks under its Pediatric Anesthesia Safety Initiative (PASI), to encourage and facilitate scientific collaboration among multiple stakeholders within a public-private partnership (PPP) framework, and to support the conduct of non-clinical and clinical studies to answer unknown questions regarding the effects of anesthetics and sedatives in the pediatric population.

As part of the Gabriella Miller Kids First Pediatric Research Program (Kids First), the NIH invites applications to use whole genome sequencing at a Kids First-supported sequencing center to elucidate the genetic contribution to childhood cancers, and to investigate the genetic etiology of structural birth defects.These data will become part of the Gabriella Miller Kids First Pediatric Data Resource (Kids First Data Resource) for the pediatric research community.

The Administration for Children and Families (ACF), Office of Planning, Research and Evaluation (OPRE), will solicit applications for Family Strengthening Research Scholars grants to support dissertation research on healthy marriage/responsible fatherhood policy issues. These grants are meant to build capacity in the research field to focus research on questions that have direct implications for healthy marriage/responsible fatherhood policy decision-making and program administration, and to foster mentoring relationships between faculty members and high-quality doctoral students. These grants are intended to address issues of significance to inform policy decisions and solutions, particularly for underserved/understudied populations (e.g., low-income families, minority populations), utilize rigorous research methodology (both primary data collection and secondary data analysis), and help inform the development of future intervention research.

This Funding Opportunity Announcement (FOA) invites applications from institutions/organizations which propose to characterize or identify factors in early childhood (birth-24 months) that may increase or mitigate risk for obesity and/or excessive weight gain and/or to fill methodological research gaps relevant to the understanding of risk for development of obesity in children. Studies should propose research in children from birth to 24 months, although any proposed follow-up assessments, if applicable, may continue past this period. Studies may also assess factors relevant to families and/or caregivers of children from birth to 24 months. Applications should seek to fill unique research needs and involve expertise across disciplines as appropriate for the proposed research question.

The purpose of this funding opportunity announcement (FOA) is to award one cooperative agreement to develop a state-of-the-art foster/adoptive parent training program to include intensive preparation and development components that reflect the capacities required of successful foster/adoptive parents. This is intended to be a product that could be utilized by all states, tribes, and territories and consistently applied wherever implemented. Development of this program would include research on the common characteristics of individuals and their foster/adoptive families that have succeeded in terms of well-being and stability. Common characteristics of families that are more likely to foster and/or adopt harder to place children/youth and are successful and remain committed to the relationship will be identified and integrated into the program. The program would be inclusive of development, training, and capacity needs of individuals/families that are interested in becoming foster parents, as well as those who are interested in fostering with the intention to eventually adopt; therefore many concepts would be in common for foster and adoptive parents. There would be particular focus for foster parents on working on reunification efforts with birth parents and for adoption there would be particular focus on the common adoption issues pertinent to all types of adoption, i.e., child welfare, private domestic, and international. The initial year would entail an extensive review of all current training and preparation programs and include new intervention strategies that foster/adoptive parents should be skilled in as they develop as foster and adoptive parents. The initial year would also involve the basic development of the new intensive training modules.

This announcement solicits applications for the Developmental Behavioral Pediatrics Research Network Program. This cooperative agreement opportunity will establish and maintain a national scientific and clinical research network that will promote and coordinate research activities in developmental, behavioral, and psychosocial aspects of pediatric care to improve clinical services and health and related outcomes for children and adolescents with autism spectrum disorder (ASD) and other developmental disabilities.

This announcement solicits applications for the Developmental Behavioral Pediatrics Research Network Program. This cooperative agreement opportunity will establish and maintain a national scientific and clinical research network that will promote and coordinate research activities in developmental, behavioral, and psychosocial aspects of pediatric care to improve clinical services and health and related outcomes for children and adolescents with autism spectrum disorder (ASD) and other developmental disabilities.

Empowers early career psychologists to produce scientifically - based research andprograms (on serious emotional disturbance) that could provide models for broad-based applications across the country. Encourages early career psychologists to devote their careers to methods of intervention and treatment for serious emotional disturbance in children.

Empowers early career psychologists to produce scientifically - based research andprograms (on serious emotional disturbance) that could provide models for broad-based applications across the country. Encourages early career psychologists to devote their careers to methods of intervention and treatment for serious emotional disturbance in children.

This encompasses basic biological processes governing differentiation and development involving both human and animal model systems, genetics and genomics of these processes, clinical studies, reproductive health and environmental toxicology. Social and behavioral studies are encouraged concerning cognitive and behavioral risks that affect outcomes of pregnancy, the perinatal period, and subsequent child development. The latter may involve family units and those genes, toxicants and social determinants that adversely affect language or behavior.

This encompasses basic biological processes governing differentiation and development involving both human and animal model systems, genetics and genomics of these processes, clinical studies, reproductive health and environmental toxicology. Social and behavioral studies are encouraged concerning cognitive and behavioral risks that affect outcomes of pregnancy, the perinatal period, and subsequent child development. The latter may involve family units and those genes, toxicants and social determinants that adversely affect language or behavior.

OJJDP invites proposals to broker, coordinate, and provide relevant training and technical assistance to organizations representing all faith traditions and to community-based institutions that are engaged with or seeking to engage with the three youth violence prevention initiatives: Â"Defending Childhood, National Forum on Youth Violence Prevention, and Community-Based Violence Prevention Program- OJJDP is funding in 39 sites nationwide.

Together with University Advancement, the Office for the Advancement of Research & Scholarship (OARS) is rolling out an new crowdfunding platform called HawksNest. Through HawksNest, alumni, family, and friends of the university can directly support the research, scholarship, and service projects of Miami University students, faculty, and staff. This is how HawksNest works: * Any Miami University student, faculty, or staff member may complete an online application to have a project considered for funding. * An internal review team assesses applications and posts approved projects on HawksNest for a maximum of 45 days. * Potential donors visit the site to learn about and pledge funds to approved projects. * Once a funding goal has been met, the project can begin! * Project managers use the site to keep donors up-to-date with information on the project's progress.

EPA and NIEHS present the NIEHS/EPA Children's Centers Webinar Series: Protecting Children's Health for a Lifetime. The webinar is co-sponsored by the National Center for Environmental Research and the Office of Children's Health Protection. The topic of the January 2016 webinar is Childhood Obesity.

The  Progeria Research Foundation is seeking proposals from principal researchers for projects related to Hutchinson-Gilford Progeria Syndrome (HGPS), a rare, fatal, "premature aging" disease that affects children.

The purpose of this graduate-level training program is to improve the health of infants, children, and adolescents who have, or are at risk for developing, autism spectrum disorder (ASD) or other neurodevelopmental and other related disabilities (DD), by expanding interdisciplinary training opportunities for graduate-level trainees from a wide variety of professional disciplines. 

The National Institutes of Health (NIH) invites applications for institutional research capacity building programs from entities/institutions in Institutional Development Award (IDeA)-eligible States that propose to support a team of experts to engage and implement pediatric clinical trials. The program aims to provide research infrastructure as well as supervised professional development in research and clinical trial implementation to assist institutions in IDeA-eligible States in establishing and maintaining pediatric clinical trial teams.

The Centers for Disease Control and Prevention's National Center for Injury Prevention and Control (NCIPC) is soliciting investigator-initiated research that will help expand and advance our understanding of how best to disseminate, implement, and translate evidence-based primary prevention strategies, programs, and policies designed to reduce child abuse and neglect. 

The U.S. Agency for International Development (USAID)'s mission in Jordan is issuing this Funding Opportunity to solicit technical applications for a five-year Health Service Delivery Activity designed to improve the health status of women of reproductive age and children underfive. USAID expects this Health Service Delivery Activity to support the resilience of the Jordanian health system to respond to the Syrian refugee crisis, by producing significant and measurable improvements in the availability and quality of reproductive, maternal, newborn, and child health (RMNCH) services, as well as decreasing the prevalence of non-communicable diseases (NCD), through innovative and scale-able service delivery approaches targeting both the public and private sectors.