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In response to The Gabriella Miller Kids First Research Act ( https://www.congress.gov/bill/113th-congress/house-bill/2019/text), NIH, through the Common Fund, has established the Gabriella Miller Kids First Pediatric Research Program (Kids First). The Kids First program is expected to be a ten-year effort (2015 - 2024) that will build the Gabriella Miller Kids First Pediatric Data Resource (Kids First Data Resource). The Kids First Data Resource will be populated by genomic and phenotypic data and will be of high value to the pediatric research community by facilitating data mining across diverse conditions. During the first five years of this Program, data were generated and made publicly available following sequencing of DNA, and some RNA, samples from pediatric cancer and structural birth defects cohorts as outlined on the Kids First Common Fund website at https://commonfund.nih.gov/kidsfirst. In addition to increased understanding of individual pediatric conditions, a goal of establishing the Data Resource is to enable discovery of shared pathways whose disruption may lead to structural birth defects and/or susceptibility to childhood cancer. Therefore, representation of a wide variety of pediatric cancers and structural birth defects within the Data Resource is essential. The overall goal is to help researchers understand the underlying mechanisms of disease, leading to more refined diagnostic capabilities and ultimately more targeted therapies or interventions.

The purpose of this funding opportunity announcement (FOA) is to stimulate research to understand the biological basis by which environmental exposures alter brain and behavioral functioning to increase risk for psychiatric disorders with onset in late-childhood, adolescence or early adulthood. A range of approaches are encouraged, from mechanistic experiments using whole organism models or in vitro and in vivo systems to human studies that add new data collection activities and/or make use of extant data or biospecimens. Investigations that further advance our understanding of the joint contribution of genes and environment in the risk for psychiatric disorders are welcomed. Applications should address either categorically defined psychiatric diagnoses and/or continuous traits expressed in the general population. Applicants are encouraged to propose studies that consider co-occurring psychiatric conditions and potential shared etiologies. It is anticipated that knowledge gained from the research supported by this FOA will inform the development of improved intervention, prevention and/or therapeutic strategies. Also listed under R21.

The Saucony Run For Good Foundation is committed to improving the lives of children by helping to prevent and reduce childhood obesity. According to the foundation, today's American youth are considered the most inactive in history and as a result the rate of obesity among U.S. children and teenagers has more than tripled over the past three decades. To that end, Saucony is inviting proposals aimed at helping run down the childhood obesity epidemic. Grants of up to $10,000 will be awarded to community-based nonprofit organizations that initiate and support running programs for kids. Program participants must be 18 years of age or younger, and the foundation will prioritize programs that serve populations not traditionally exposed to running programs.

The purpose of this Notice of Funding Opportunity Announcement (NOFO) is to conduct surveillance to assess the incidence and prevalence of diabetes among children, adolescents and young adults in the United States and provide estimates by diabetes type, age, sex, race/ethnicity and geographic area. This NOFO has three (3) components to achieve the purpose of the program * Component A focuses on surveillance of incidence and prevalence of diabetes among children and adolescents (<45 years). * Component C serves as a Coordinating Center to provide an infrastructure for standardized approaches, analytical methods, and surveillance measures. It also serves as a repository for the Component A and B data and provides consolidated estimates by diabetes type, age, race/ethnicity and geographic area.

The purpose of this Funding Opportunity Announcement (FOA) is to invite applications for multidisciplinary national conferences that will inform care and facilitate research for major issues in pediatric critical care medicine. Given the nascent stage of development, the small diverse patient populations, and the rapid expansion of the field, conducting research and establishing best practices in pediatric critical care is challenging. National conferences that convene experts from across the country hold the potential to establish the frameworks necessary to overcome these obstacles. It is anticipated that such conferences will foster collaboration among different clinical disciplines, geographically and culturally diverse institutions and medical centers, professional organizations and NIH Institutes. Specifically, it is hoped that these conferences will drive the development and acceptance of uniform definitions, facilitate the determination of common data elements, identify key knowledge gaps to advance research, and/or foster discussions on how research findings can be used to best inform guidelines for patient care.

The purpose of this funding opportunity announcement (FOA) is to promote initial establishment of basic science-clinical collaborations by providing small grants to teams of basic scientists, physician scientists, and/or clinicians. These interdisciplinary teams may include but are not limited to the following: developmental biologists, cell biologists, geneticists, genomicists, physician scientists including individuals with DVM/VMD degrees, clinicians, epidemiologists, biostatisticians, and/or bioinformaticists.