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The Centers of Excellence in Genomic Science (CEGS) program establishes academic Centers for advanced genome research.  Each CEGS grant supports a multi-investigator, interdisciplinary team to develop innovative genomic approaches to address a particular biomedical problem.  A CEGS project will address a critical issue in genomic science or genomic medicine, proposing a solution that would be a very substantial advance.  Thus, the research conducted at these Centers will entail substantial risk, balanced by outstanding scientific and management plans and very high potential payoff.  A CEGS will focus on the development of novel technological or computational methods for the production or analysis of comprehensive data sets, or on a particular genome-scale biomedical problem, or on other ways to develop and use genomic approaches for understanding biological systems and/or significantly furthering the application of genomic knowledge, data and methods towards clinical applications.  Exploiting its outstanding scientific plan and team, each CEGS will nurture genomic science at its institution by facilitating the interaction of investigators from different disciplines, and by providing training to new and experienced investigators, it will expand the pool of highly-qualified professional genomics scientists and engineers.

The Centers of Excellence in Genomic Science (CEGS) program establishes academic Centers for advanced genome research.  Each CEGS grant supports a multi-investigator, interdisciplinary team to develop innovative genomic approaches to address a particular biomedical problem.  A CEGS project will address a critical issue in genomic science or genomic medicine, proposing a solution that would be a very substantial advance.  Thus, the research conducted at these Centers will entail substantial risk, balanced by outstanding scientific and management plans and very high potential payoff.  A CEGS will focus on the development of novel technological or computational methods for the production or analysis of comprehensive data sets, or on a particular genome-scale biomedical problem, or on other ways to develop and use genomic approaches for understanding biological systems and/or significantly furthering the application of genomic knowledge, data and methods towards clinical applications.  Exploiting its outstanding scientific plan and team, each CEGS will nurture genomic science at its institution by facilitating the interaction of investigators from different disciplines, and by providing training to new and experienced investigators, it will expand the pool of highly-qualified professional genomics scientists and engineers.

The National Science Foundation (NSF) seeks to enhance opportunities for collaborative activities between U.S. and foreign investigators. To realize this goal, the Division of Chemistry at NSF has partnered with the Fonds zur Förderung der wissenschaftlichen Forschung (Austrian Science Fund) of Austria (FWF), the Fundação de Amparo à Pesquisa do Estado de São Paulo (Foundation for Research Support of the State of São Paulo), Brazil (FAPESP), the Agence Nationale de la Recherche (National Agency for Research) of France (ANR), the U.S.-Israel Binational Science Foundation (BSF), Japan Society for the Promotion of Science (JSPS), the National Research Foundation of Korea (NFR), the Fonds National de la Recherche (National Research Fund) of Luxembourg (FNR), the Russian Foundation for Basic Research (RFBR), and the National Science Council of Taiwan (NSC). The NSF Division of Chemistry will accept collaborative research proposals in basic research in chemistry, written in English, which establish bilateral collaborations between US investigators and investigators from the countries listed above.

The Experimental Program to Stimulate Competitive Research (EPSCoR) is a program designed to fulfill the National Science Foundation's (NSF) mandate to promote scientific progress nationwide. The EPSCoR program is directed at jurisdictions that have historically received lesser amounts of NSF Research and Development (R&D) funding. Thirty-one jurisdictions including twenty-eight states, the Commonwealth of Puerto Rico, the U. S. Virgin Islands, and Guam currently are eligible to participate. Through this program, NSF establishes partnerships with government, higher education, and industry that are designed to effect lasting improvements in a state's or region's research infrastructure, R&D capacity and hence, its national R&D competitiveness.Research Infrastructure Improvement Program: Track-2 (RII Track-2) awards provide funds in the range of $1.5 to 2.0 million per year for up to 3 years to consortia of EPSCoR jurisdictions. The awards promote opportunities for collaborations among EPSCoR jurisdictions in all areas of science, engineering, and education supported by the National Science Foundation (NSF). RII Track-2 proposals must describe a clear, comprehensive, and integrated vision to drive discovery, and train a skilled workforce capable of solving science and engineering challenges of regional, thematic, and national relevance. Proposals should also include a strong rationale for the establishment of the consortium and clearly demonstrate that the consortium is well-positioned to produce results that cannot be obtained by any single partner working independently. The Science, Technology, Engineering, and Mathematics (STEM) research and education activities should broaden participation by different types of institutions, individuals, and sectors in the project.

The purpose of the Mentored Quantitative Research Career Development Award (K25) is to attract to NIH-relevant research those investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease. The K25 award will provide support and "protected time" for a period of supervised study and research for productive professionals with quantitative (e.g., mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry) and engineering backgrounds to integrate their expertise with NIH-relevant research. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing to lead basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should submit under this FOA include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Studies conducted with specific applications toward processes or products in mind should submit under the companion PA-18-395.

The purpose of this Dear Colleague Letter is to advise you about funding opportunities at the National Science Foundation for the research community to propose research projects or workshops that will gather data on the implementation and impacts of recent science policy initiatives including, but not limited to those noted earlier.  Especially encouraged are proposals that will: Develop new, or improve existing, analytical frameworks for evaluating the impacts of federal science policy initiatives; Explore different agencies' approaches to the implementation of particular policies to examine how variations in approach affect the achievement of intended policy outcomes; Collect case-study or quantitative data that facilitate identification of best practices in science and innovation policy implementation.

This Dear Colleague Letter is to alert all basic science and engineering communities, including education researchers, to the Foundation's interest in receiving proposals that, while investigating fundamental questions, seek to pose and test hypotheses that could inform research in forensic sciences. The interest spans both disciplinary and interdisciplinary research. Additionally, the wide public interest in forensics can provide an effective vehicle for basic research in science education. International partnerships, where appropriate, are encouraged, as are synergistic interactions with forensics and/or law enforcement agencies and organizations. Proposals for workshops to explore fundamental science drivers and their relevance to forensics are also welcome. 

The Special Grant Program in the Chemical Sciences provides funding for innovative projects in any area consistent with the Foundation's broad objective to advance the chemical sciences. The Foundation encourages proposals that are judged likely to significantly advance the chemical sciences. Examples of areas of interest include (but are not limited to): the increase in public awareness, understanding, and appreciation of the chemical sciences; innovative approaches to chemistry education at all levels (K-12, undergraduate, and graduate); and efforts to make chemistry careers more attractive. Research proposals are not customarily considered. Aspects of proposals that are important are: * broad applicability beyond the submitting institution * specific and detailed descriptions of the chemistry associated with the proposal * uniqueness of the project Favorable consideration also is given to: * a plan for sustaining this project, if relevant * significant institutional support or other sources of funding * evidence of expertise of the PIs and/or identified consultants * plans to assess effectiveness, including over the longer term

Partnerships for International Research and Education (PIRE) is an NSF-wide program that supports international activities across all NSF supported disciplines. The primary goal of PIRE is to support high quality projects in which advances in research and education could not occur without international collaboration. PIRE seeks to catalyze a higher level of international engagement in the U.S. science and engineering community. International partnerships are essential to addressing critical science and engineering problems. In the global context, U.S. researchers and educators must be able to operate effectively in teams with partners from different national environments and cultural backgrounds. PIRE promotes excellence in science and engineering through international collaboration and facilitates development of a diverse, globally-engaged, U.S. science and engineering workforce.

NSF and selected foreign counterpart science and technology agencies sponsor international research institutes for U.S. graduate students in seven East Asia and Pacific locations at times set by the counterpart agencies between June and August each year. The Summer Institutes (EAPSI) operate similarly and the research visits to a particular location take place at the same time. Although applicants apply individually to participate in a Summer Institute, awardees become part of the cohort for each location. Applicants must propose a location, host scientist, and research project that is appropriate for the host site and duration of the international visit. An EAPSI award provides U.S. graduate students in science, engineering, and education: 1) first-hand research experiences in Australia, China, Japan, Korea, New Zealand, Singapore, or Taiwan; 2) an introduction to the science, science policy, and scientific infrastructure of the respective location; and 3) an orientation to the society, culture, and language. It is expected that EAPSI awards will help students initiate professional relationships to enable future collaboration with foreign counterparts. The NSF award includes participation in the Pre-Departure Orientation, summer stipend of $5,000, and roundtrip airplane ticket to the host location. EAPSI partner agencies pay in-country living expenses during the Summer Institutes.

The Hydrologic Sciences Program focuses on the fluxes of water in the environment that constitute the water cycle as well as the mass and energy transport function of the water cycle in the environment.  The Program supports studying processes from rainfall to runoff to infiltration and streamflow; evaporation and transpiration; as well as the flow of water in soils and aquifers and the transport of suspended, dissolved and colloidal components.  Water is seen as the mode of coupling among various components of the environment and emphasis is placed on how the coupling is enabled by the water cycle and how it functions as a process.  The Hydrologic Sciences Program retains a strong focus on linking the fluxes of water and the components carried by water across the boundaries between various interacting components of the terrestrial system and the mechanisms by which these fluxes co-organize over a variety of timescales and/or alter the fundamentals of the interacting components.  The Program is also interested in how water interacts with the solid phase, the landscape and the ecosystem as well as how such interactions and couplings are altered by land use and climate change.  Studies may address aqueous geochemistry and solid phase interactions as well as physical, chemical, and biological processes as coupled to water transport. These studies commonly involve expertise from basic sciences and mathematics, and proposals may require joint review with related programs.  The Hydrologic Sciences Program will also consider some synthesis activities.

The Office of Research, Development, Test, and Evaluation, under Defense Programs within the Department of Energy's (DOE) National Nuclear Security Administration (NNSA), announce their interest in receiving grant applications for new or renewal awards for research in the Stewardship Science Academic Alliances (SSAA) Program. The SSAA Program, established in 2002, was developed to support state-of-the-art research at U.S. academic institutions in areas of fundamental physical science and technology of relevance to the Stockpile Stewardship Program mission, with a focus on those areas not supported by other federal agencies. For purposes of this FOA, the research areas of interest are: properties of materials under extreme conditions and/or hydrodynamics (condensed matter physics and materials science, and fluid dynamics); low energy nuclear science; and radiochemistry.

The National Science Foundation (NSF), through its Divisions of Electrical, Communications and Cyber Systems (ECCS), Computing and Communication Foundations (CCF), Molecular and Cellular Biosciences (MCB), and Materials Research (DMR) announces a follow-up solicitation on the Semiconductor Synthetic Biology for Information Storage and Retrieval Program (SemiSynBio-II).  Future ultra-low energy storage-based computing systems can be built on principles derived from organic systems that are at the intersection of physics, chemistry, biology, computer science and engineering.  Next-generation information storage technologies can be envisioned that are driven by biological principles and use biomaterials in the fabrication of devices and systems that can store data for more than 100 years with storage capacity 1,000 times more than current storage technologies.  Such a research effort can have a significant impact on the future of information storage and retrieval technologies. This focused solicitation seeks high-risk/high-return interdisciplinary research on novel concepts and enabling technologies that will address the fundamental scientific issues and technological challenges associated with the underpinnings of synthetic biology integrated with semiconductor technology. This research will foster interactions among various disciplines including biology, physics, chemistry, materials science, computer science and engineering that will enable in heretofore unanticipated breakthroughs.

The National Science Foundation Directorates for Mathematical and Physical Sciences (MPS), Computer and Information Science and Engineering (CISE), Engineering (ENG), and the Simons Foundation Division of Mathematics and Physical Sciences will jointly sponsor up to two new research collaborations consisting of mathematicians, statisticians, electrical engineers, and theoretical computer scientists. Research activities will be focused on explicit topics involving some of the most challenging questions in the general area of Mathematical and Scientific Foundations of Deep Learning. Each collaboration will conduct training through research involvement of recent doctoral degree recipients, graduate students, and/or undergraduate students from across this multi-disciplinary spectrum. Annual meetings of the Principal Investigators ("PIs") and other principal researchers involved in the collaborations will be held at the Simons Foundation in New York City. This program complements NSF's National Artificial Intelligence Research Institutes program by supporting collaborative research focused on the mathematical and scientific foundations of Deep Learning through a different modality and at a different scale.

The National Science Foundation (NSF) Directorates for Engineering (ENG) and Geosciences (GEO), the Divisions of Integrative Organismal Systems (IOS) and Environmental Biology (DEB), in the Directorate for Biological Sciences (BIO), the Division of Computer and Network Systems in the Directorate Computer and Information Science and Engineering (CISE/CNS), and the Division of Chemistry (CHE) in the Directorate for Mathematical and Physical Sciences, in collaboration with the US Department of Agriculture National Institute of Food and Agriculture (USDA NIFA) encourage convergent research that transforms existing capabilities in understanding dynamic soil processes, including soil formation, through advances in sensor systems and modeling. The Signals in the Soil (SitS) program fosters collaboration among the two partner agencies and the researchers they support by combining resources and funding for the most innovative and high-impact projects that address their respective missions. To make transformative advances in our understanding of soils, multiple disciplines must converge to produce environmentally-benign novel sensing systems with multiple modalities that can adapt to different environments and collect and transmit data for a wide range of biological, chemical, and physical parameters. Effective integration of sensor data will be key for achieving a better understanding of signaling interactions among plants, animals, microbes, the soil matrix, and aqueous and gaseous components. New sensor networks have the potential to inform models in novel ways, to radically change how data is obtained from various natural and managed (both urban and rural) ecosystems, and to better inform the communities that directly rely on soils for sustenance and livelihood.

The primary objective is to support scholarships for nuclear science, engineering, technology and related disciplines to develop a workforce capable of supporting the design, construction, operation, and regulation of nuclear facilities and the safe handling of nuclear materials. The primary objective is to support fellowships for nuclear science, engineering, technology and related disciplines to develop a workforce capable of supporting the design, construction, operation, and regulation of nuclear facilities and the safe handling of nuclear materials. The primary objective is to support faculty development for nuclear science, engineering, technology and related disciplines to develop a workforce capable of supporting the design, construction, operation, and regulation of nuclear facilities and the safe handling of nuclear materials. The grants specifically target probationary, tenure-track faculty during the first 6 years of their career and new faculty hires in the following academic areas: Nuclear, Mechanical, Civil, Environmental, Electrical, Fire Protection, Geotechnical, Structural and Materials Sciences Engineering as well as Health Physics. The program provides support to enable newer faculty to enhance their careers as professors and researchers in the university department where employed.

The purpose of the Cyberlearning for Work at the Human-Technology Frontier program is to fund exploratory and synergistic research in learning technologies to prepare learners to excel in work at the human-technology frontier. This program responds to the pressing societal need to educate and re-educate learners of all ages (students, teachers and workers) in science, technology, engineering, and mathematics (STEM) content areas to ultimately function in highly technological environments, including in collaboration with intelligent systems. Innovative technologies can reshape learning processes, which in turn can influence new technology design. Learning technology research in this program should be informed by the convergence of multiple disciplines: education and learning sciences, computer and information science and engineering, and cognitive, behavioral and social sciences. This program funds learning technology research in STEM and other foundational areas that enable STEM learning.

The National Science Foundation (NSF), through its Divisions of Electrical, Communications and Cyber Systems (ECCS), Computing and Communication Foundations (CCF), Molecular and Cellular Biosciences (MCB), and Materials Research (DMR) announces a follow-up solicitation on the Semiconductor Synthetic Biology for Information Storage and Retrieval Program (SemiSynBio-II). Future ultra-low energy storage-based computing systems can be built on principles derived from organic systems that are at the intersection of physics, chemistry, biology, computer science and engineering. Next-generation information storage technologies can be envisioned that are driven by biological principles and use biomaterials in the fabrication of devices and systems that can store data for more than 100 years with storage capacity 1,000 times more than current storage technologies. Such a research effort can have a significant impact on the future of information storage and retrieval technologies. This focused solicitation seeks high-risk/high-return interdisciplinary research on novel concepts and enabling technologies that will address the fundamental scientific issues and technological challenges associated with the underpinnings of synthetic biology integrated with semiconductor technology. This research will foster interactions among various disciplines including biology, physics, chemistry, materials science, computer science and engineering that will enable in heretofore unanticipated breakthroughs.

The National Science Foundation (NSF) invites investigators at U.S. organizations to submit proposals to conduct research about the Arctic. Arctic research includes field and modeling studies, data analysis, and synthesis about the arctic region.The goal of the NSF Section for Arctic Sciences, Division of Polar Programs (PLR),??is to gain a better understanding of the Arctic's physical, biological, geological, chemical, social and cultural processes; the interactions of oceanic, terrestrial, atmospheric, biological, social, cultural, and economic systems; and the connections that define the Arctic. The Arctic Sciences and other NSF programs support projects that contribute to the development of the next generation of researchers and scientific literacy for all ages through education, outreach, and broadening participation in science, technology, engineering, and mathematics. Program representatives from polar and other non-polar NSF programs that support arctic research coordinate across NSF, including joint review and funding of arctic proposals and mutual support of special projects with high logistical costs.

The Science and Technology Centers (STC): Integrative Partnerships program supports innovative, potentially transformative, complex research and education projects that require large-scale, long-term awards. STCs conduct world-class research through partnerships among academic institutions, national laboratories, industrial organizations, and/or other public/private entities, and via international collaborations, as appropriate. They provide a means to undertake significant investigations at the interfaces of disciplines and/or fresh approaches within disciplines. STCs may involve any area of science and engineering that NSF supports. STC investments support the NSF vision of creating and exploiting new concepts in science and engineering and providing global leadership in research and education.

The Office of Basic Energy Sciences (BES), U.S. Department of Energy (DOE), announces its interest in receiving applications from single investigator or small groups of investigators for support of experimental and theoretical efforts to advance materials and chemical sciences research for quantum information sciences (QIS).