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The Early Investigator Research Award supports prostate cancer-focused research opportunities for individuals in the early stages of their careers, under the guidance of one or more designated Mentors. This opportunity allows for early-career investigators to develop a research project, investigate a problem or question in prostate cancer research, and further their intellectual development as prostate cancer researchers of the future. All application components for the Early Investigator Research Award are to be written by the Principal Investigator (PI), with appropriate direction from the Mentor(s).

The Physician Research Award supports a mentored research experience to prepare physicians with clinical duties and/or responsibilities for productive careers in prostate cancer research. The mentored physician is considered the Principal Investigator (PI) of the application. This award emphasizes equally the quality of the proposed research project and the career development of the PI, which should prepare physicians for careers in basic, population science, translational, or clinical prostate cancer research. All applications for the Physician Research Award are to be written by the PI, with appropriate direction from the Mentor(s).

This Funding Opportunity Announcement (FOA) invites R21 applications for studies that address knowledge gaps in mechanisms of Fc-dependent, antibody-mediated killing of infected cells or aberrant cells, or antibody-mediated therapeutic ablation of cells implicated in immune pathologies, including autoimmune and allergic diseases. More specifically, the purpose of this FOA is to promote innovative and exploratory research to elucidate mechanisms of antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cell-mediated phagocytosis (ADCP), and to promote development of tools, technologies, and animal models to facilitate identification and evaluation of cytotoxic killing mechanisms mediated by human antibodies in vivo.

The Fusion Energy Sciences (FES) program of the Office of Science (SC) and the Defense Program (DP) of the National Nuclear Security Administration (NNSA), both of the U.S. Department of Energy (DOE), jointly announce their interests in receiving grant applications for new awards and grant renewals for research in the SC-NNSA Joint Program in High-Energy-Density (HED) laboratory plasmas. All individuals or groups planning to submit applications for new or renewal funding in Fiscal Year 2018 should submit in response to this Funding Opportunity Announcement (FOA). The specific areas of interest are: 1. HED Hydrodynamics 2. Radiation-Dominated Dynamics and Material Properties 3. Magnetized HED Plasma Physics 4. Nonlinear Optics of Plasmas and Laser-Plasma Interactions 5. Relativistic HED Plasmas and Intense Beam Physics 6. Warm Dense Matter 7. High-Z, Multiply Ionized HED Atomic Physics 8. Diagnostics for HED Laboratory Plasmas More specific information on each area of interest is outlined in the general and program specific supplementary information provided.