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This Funding Opportunity Announcement (FOA) supports Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that will develop and/or validate devices or electronic systems that can: 1) monitor biologically- or behaviorally-based processes applicable to mind and body interventions or 2) be used to assist in optimizing the practice or increasing the efficacy of mind and body interventions.  The applications should: 1) lead to the development of new technologies, 2) adapt existing innovative technologies, devices and/or electronic systems, 3) repurpose existing devices and electronic systems, or 4) conduct testing of single or combined components of an integrated, long term, automated, wearable monitoring, stimulation device or electronic system in order to monitor or enhance the mechanistic processes or functional outcomes of mind and body interventions. For the purposes of this FOA, mind and body interventions are defined as non-pharmacological approaches that include mind/brain focused interventions (e.g., meditation, hypnosis), body-based approaches (e.g., acupuncture, massage, spinal manipulation/mobilization), or combined mind and body meditative movement approaches (e.g., yoga, tai-chi, qigong).  

This program supports theoretical and computational materials research and education in the topical areas represented in DMR programs, including condensed matter physics, polymers, solid-state and materials chemistry, metals and nanostructures, electronic and photonic materials, ceramics, and biomaterials. The program supports fundamental research that advances conceptual, analytical, and computational techniques for materials research. A broad spectrum of research is supported using electronic structure methods, many-body theory, statistical mechanics, and Monte Carlo and molecular dynamics simulations, along with other techniques, many involving advanced scientific computing. Emphasis is on approaches that begin at the smallest appropriate length scale, such as electronic, atomic, molecular, nano-, micro-, and mesoscale, required to yield fundamental insight into material properties, processes, and behavior and to reveal new materials phenomena. Areas of recent interest include, but are not limited to: strongly correlated electron systems; low-dimensional systems; nonequilibrium phenomena, including pattern formation, microstructural evolution, and fracture; high-temperature superconductivity; nanostructured materials and mesoscale phenomena; quantum coherence and its control; and soft condensed matter, including systems of biological interest.

A. Proposals for the development of novel collaborative perception algorithms that will enable heterogeneous teams of UxS (specifically unmanned air and ground systems) to share knowledge and perform joint target search and tracking autonomously. While existing distributed data fusion methods have looked at probabilistic representations for fusing detections at a decision level, work is needed to investigate shared perceptual features that exist across unmanned air and ground systems to enable the performance of collaborative tasks.  B. Development of a new Rigid Body Dynamics Software Library for Mathematical and Physics-Based Modeling and Simulation. The basic research proposed here would involve the development of a new software library for the temporal (time) integration of the governing equations of rigid body dynamics. The temporal integration technique employed in this new library involves the application of the Runge-Kutta method of various orders and possibly other finite-difference-type techniques to a system of equations consisting of kinematic equations (arising from the Lie Group structure of the group of rotation transformations) which define the first and second time derivatives of the rotation transformation in terms of angular velocity and angular acceleration together with the equations of motion (balance of momentum and balance of angular momentum) of a rigid body. C. Robustness of the Use of Botanical DNA Materials as Anti-Counterfeit Markers for Electronic Components - The project will solicit academic laboratory participation for doing testing that demonstrates the 'robustness' of the use of Botanical DNA material as anti-counterfeit markers for electronic components. Request analysis of candidate DNA marker materials utilizing current DNA manipulation technology. This would be done especially in light of results from (1) above.

The purpose of this Funding Opportunity Announcement (FOA) is to provide regional access for cryoelectron microscopy (cryoEM) laboratories to state-of-the-art data collection capabilities.  NIGMS will support consortia of established and early stage investigator laboratories whose research has an established specialization in and dependence on cryoEM.  These laboratories will coordinate with each other to share facilities and resources for direct electron detection.  Consortia will consist of a host institution which already has a modern high-performing cryoEM installation and proven capabilities for high-resolution data collection, partnered with regional participating institutions.  A consortium will support surplus capacity for cryoEM data collection (infrastructure and services) at the host institution and make it available as a resource for the participating regional institutions.  Projects will support access for cryoEM laboratories at participating institutions to resources and services at host sites.  Projects will (a) contribute to the fixed costs of maintaining the host facility and extend services in proportion to the resources dedicated to the regional users and (b) support access to the facility by the regional laboratories.  The host institution need not already have an electron detector; this FOA can help fund acquisition of direct detection equipment.  Support is limited to enabling the participating cryoEM laboratories to collect data and perform the initial stages of processing raw images, and does not include other research activities.  Consortia will consist of a minimum of 3-5 institutions; award budgets will depend on the number and data collection needs of the regional participating cryoEM laboratories.  This initiative is not intended to support service centers of the traditional type in which the host laboratory performs the cryoEM analysis for non-specialist collaborators. 

The purpose of this Funding Opportunity Announcement (FOA) is to provide regional access for cryoelectron microscopy (cryoEM) laboratories to state-of-the-art data collection capabilities. NIGMS will support consortia of established and early stage investigator laboratories whose research has an established specialization in and dependence on cryoEM. These laboratories will coordinate with each other to share facilities and resources for direct electron detection. Consortia will consist of a host institution which already has a modern high-performing cryoEM installation and proven capabilities for high-resolution data collection, partnered with regional participating institutions. A consortium will support surplus capacity for cryoEM data collection (infrastructure and services) at the host institution and make it available as a resource for the participating regional institutions. Projects will support access for cryoEM laboratories at participating institutions to resources and services at host sites. Projects will (a) contribute to the fixed costs of maintaining the host facility and extend services in proportion to the resources dedicated to the regional users and (b) support access to the facility by the regional laboratories. The host institution need not already have an electron detector; this FOA can help fund acquisition of direct detection equipment. Support is limited to enabling the participating cryoEM laboratories to collect data and perform the initial stages of processing raw images, and does not include other research activities. Consortia will consist of a minimum of 3-5 institutions; award budgets will depend on the number and data collection needs of the regional participating cryoEM laboratories. This initiative is not intended to support service centers of the traditional type in which the host laboratory performs the cryoEM analysis for non-specialist collaborators.

CMMT supports theoretical and computational materials research in the topical areas represented in DMR's Topical Materials Research Programs (these are also variously known as Individual Investigator Award (IIA) Programs, or Core Programs, or Disciplinary Programs), which include: Condensed Matter Physics (CMP), Biomaterials (BMAT), Ceramics (CER), Electronic and Photonic Materials (EPM), Metals and Metallic Nanostructures (MMN), Polymers (POL), and Solid State and Materials Chemistry (SSMC). The CMMT program supports fundamental research that advances conceptual understanding of hard and soft materials, and materials-related phenomena; the development of associated analytical, computational, and data-centric techniques; and predictive materials-specific theory, simulation, and modeling for materials research.Research may encompass the advance of new paradigms in materials research, including emerging data-centric approaches utilizing data-analytics or machine learning. Computational efforts span from the level of workstations to advanced and high-performance scientific computing. Emphasis is on approaches that begin at the smallest appropriate length scale, such as electronic, atomic, molecular, nano-, micro-, and mesoscale, required to yield fundamental insight into material properties, processes, and behavior, to predict new materials and states of matter, and to reveal new materials phenomena. Approaches that span multiple scales of length and time may be required to advance fundamental understanding of materials properties and phenomena, particularly for polymeric materials and soft matter.

The purpose of the FOA is to support the structural characterization of protein species associated with Alzheimer's Disease Related Dementias (ADRDs) through the utilization of cryo-electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET) of proteins expressed in human tissue and cell sources. Studies in response to this RFA should also include the development of research tools and resources to further characterize/validate the protein species. This FOA is in response to the Alzheimer's Disease Related Dementias (ADRD) challenges outlined in the 2016 update to the National Plan to Address Alzheimer's Disease.

The purpose of this funding opportunity announcement is to support studies on electronic nicotine delivery systems (ENDS) that examine population-based, clinical and applied prevention of disease, including etiology of use, epidemiology of use, potential risks, benefits and impacts on other tobacco use behavior among different populations.

This Funding Opportunity Announcement (FOA) encourages research project grant (R01) applications to leverage large-scale, real-world data from electronic health records (EHRs) from a variety of systems (e.g., the Department of Defense (DOD), Department of Veterans Affairs (VA), Centers for Medicare and Medicaid Services administrative claims, as well as public or private health care systems and networks) to understand risk, onset, course, and impact of treatments and services for mental and neurological disorders and to identify promising new mental health and neurological disorders research. There is particular interest in leveraging EHRs and administrative data to 1) understand and improve the treatment of post traumatic psychopathology, including posttraumatic stress disorder, depression, traumatic brain injury (TBI), and risk for suicide; and 2) characterize post-trauma multi-symptom recovery trajectory patterns of TBI, that may include post traumatic stress disorder, depression, cognitive impairment, pain, substance abuse disorder and risk for suicide. NIMH also invites innovative approaches to use EHR and administrative data to understand risk, onset, course, and impact of treatments and services for mental disorders more broadly.

The purpose of this funding opportunity announcement is to support studies on electronic nicotine delivery systems (ENDS) that examine population-based, clinical and applied prevention of disease, including etiology of use, epidemiology of use, potential risks, benefits and impacts on other tobacco use behavior among different populations.

The purpose of this funding opportunity announcement is to support basic research examining how Electronic Nicotine Delivery Systems (ENDS) aerosols affect normal and disease states relevant to human cells, tissues and organs.

The Small Business Innovation Research (SBIR) Program stimulates technological innovation in the private sector by strengthening the role of small business concerns in meeting Federal research and development needs, increasing the commercial application of federally supported research results, and fostering and encouraging participation by socially and economically disadvantaged and women-owned small businesses. The SBIR program solicits proposals from the small business sector consistent with NSF's mission. The program is governed by Public Law 112-81 (SBIR/STTR Reauthorization Act of 2011). A main purpose of the legislation is to stimulate technological innovation and increase private sector commercialization. The NSF SBIR program is therefore in a unique position to meet both the goals of NSF and the purpose of the SBIR legislation by transforming scientific discovery into both social and economic benefit, and by emphasizing private sector commercialization. Accordingly, NSF has formulated broad solicitation topics for SBIR that conform to the high-technology investment sector's interests. The topics are: Biological and Chemical Technologies (BC) Education Applications (EA) Electronics, Information and Communication Technologies (EI) Nanotechnology, Advanced Materials, and Manufacturing (NM)

The Small Business Innovation Research (SBIR) Program stimulates technological innovation in the private sector by strengthening the role of small business concerns in meeting Federal research and development needs, increasing the commercial application of federally supported research results, and fostering and encouraging participation by socially and economically disadvantaged and women-owned small businesses. The topics, listed below, are detailed on the SBIR/STTR topics homepage: Educational Technologies and Applications (EA) Information and Communication Technologies (IC) Semiconductors (S) and Photonic (PH) Devices and Materials Electronic Hardware, Robotics and Wireless Technologies (EW) Advanced Manufacturing and Nanotechnology (MN) Advanced Materials and Instrumentation (MI) Chemical and Environmental Technologies (CT) Biological Technologies (BT) Smart Health (SH) and Biomedical (BM) Technologies

DARPA is soliciting innovative research proposals in the field of UV laser technology that will enable enhanced detection and discrimination of specific biological and chemical compounds using Raman spectroscopy. The goal of the Laser UV Sources for Tactical Efficient Raman (LUSTER) program is to develop compact, efficient, high-power ultraviolet lasers capable of achieving output power >1 W, wall-plug efficiency >10%, linewidth < 0.01 nm and all at wavelengths between 220-240 nm. Various methods such as direct electrical injection, electron beam pumping, second harmonic generation or other alternatives will be considered as long as all of the metrics can be met or exceeded. See the full DARPA-BAA-14-20 document attached.

The purpose of this Funding Opportunity Announcement (FOA) in Malawi is to strengthen the laboratory systems by training human resources, improving laboratory infrastructure, building capacity in data management and use, and improving quality management systems. The objectives are to provide pre-service and in-service training for various cadre or laboratory staff, and to equip and perform alterations and refurbishments to at least 10 laboratories to perform essential microbiology, mycobacteriology, parasitology, hematology and chemistry. The FOA will also develop laboratory information management systems (LIMS) and improve the use of generated data in decision making, increase quality by supporting laboratories to develop and adhere to quality management systems (QMS), and strengthen quality control and quality assurance. The activities of the program will include health systems strengthening by increasing human resources, implementing necessary alterations and refurbishment to physical infrastructure, improving the specimen referral system, and improving data generation and handling capabilities through an electronic information system.

The Shared Instrument Grant (SIG) program encourages applications from groups of NIH-supported investigators to purchase or upgrade a single item of expensive, specialized, commercially available instruments or integrated systems that cost at least $50,000. The maximum award is $600,000. Types of instruments supported include, but are not limited to: X-ray diffraction systems, nuclear magnetic resonance (NMR) and mass spectrometers, DNA and protein sequencers, biosensors, electron and confocal microscopes, cell-sorters, and biomedical imagers.

Any area of education related to the radiologic sciences is eligible for Education Scholar Grant support. Projects may include, but are not limited to: advanced training in the discipline of education, possibly resulting in an advanced degree/certificate (development of teachers and educational leaders); development, dissemination and evaluation of printed or electronic educational materials; research of teaching methods and evaluation processes; education in emerging nations; medical student, resident, fellow, CME participant, allied health professional student education. RSNA and the Association of University Radiologists (AUR) have collaborated on a joint award beginning in 2013. This co-sponsored Education Scholar Grant will leverage funds to support additional projects in radiology education. Interested applicants should apply through the standard application process.

The U.S. Army Medical Research and Materiel Command's (USAMRMC) mission is to provide solutions to medical problems of importance to the American Service member at home and abroad, as well as to the general public at large. The scope of this effort and the priorities attached to specific projects are influenced by changes in military and civilian medical science and technology, operational requirements, military threat assessments, and national defense strategies. The extramural research and development programs play a vital role in the fulfillment of the objectives established by the USAMRMC. General information on USAMRMC can be obtained at https://mrmc.detrick.army.mil/. This Fiscal Year 2015 (FY15) Broad Agency Announcement (BAA) is intended to solicit extramural research and development ideas and is issued under the provisions of the Competition in Contracting Act of 1984 (Public Law 98-369), as implemented in Federal Acquisition Regulation (FAR) 6.102(d)(2) and 35.016. In accordance with FAR 6.102, projects funded under this BAA must be for basic and applied research and that part of development not related to the development of a specific system or hardware procurement. Projects must be for scientific study and experimentation directed toward advancing the state-of-the-art or increasing knowledge or understanding rather than focusing on a specific system or hardware solution. Research and development funded through this BAA is intended and expected to benefit and inform both military and civilian medical practice and knowledge. This FY15 BAA is continuously open for a 12-month period, from October 1, 2014 through September 30, 2015, at 11:59 p.m. Eastern Time. Submission of a pre-proposal/pre-application is required and must be submitted through the new electronic Biomedical Research Application Portal (eBRAP) (https://eBRAP.org/). Pre-proposal/pre-applications may be submitted at any time throughout the 12-month period. If the USAMRMC is interested in rece

The purpose of this Funding Opportunity Announcement (FOA) is to support research aimed at understanding the biological and physiological effects of aerosol mixtures produced by electronic cigarettes (ECs) on cells, tissues and organs of the oral cavity including oral and periodontal epithelia, gingiva, salivary glands, and tooth. This FOA will also support research on elucidation of the effects of ECs on oral microbiome.  Research supported by this FOA would provide essential and necessary information on the biological effects of ECs that would in turn lead to evidence based foundational information for health policy decisions.

This program supports theoretical and computational materials research and education in the topical areas represented in DMR programs, including condensed matter physics, polymers, solid-state and materials chemistry, metals and nanostructures, electronic and photonicmaterials, ceramics, and biomaterials. The program supports fundamental research that advances conceptual, analytical, and computational techniques for materials research.