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The purpose of this funding announcement (FA) is to solicit applications for Genome Centers to generate and process genomic data as part of the All of Us Research Program. The All of Us Research Program seeks to create one of the world's largest and most comprehensive precision medicine research platforms with a data resource containing multi-layered data on one million or more participants. The All of Us Genome Centers will generate both genotype and whole genome sequence data from biospecimens from this cohort. These Centers also will operate an analysis workflow resulting in high-confidence calling of all variant types (single nucleotide variants, small insertions/deletions, larger structural variants including copy number variations) and establish a robust pipeline to securely transfer data to the All of Us Data and Research Center

The PCC has supported world-class research since 2009, spending more than $8.0 M to support novel science. Research and grant-making are the foundation of the PCC and are the focus of everyday business activity. PCC-supported research contributes to a movement in addressing doping's root causes and ultimately decreasing the use of performance-enhancing drugs by all participants in all sports at all levels of play. With an emphasis on original work that focuses on improving existing analytical methods for detecting particular drugs, developing new analytical methods to test for substances not currently detectable, and discovering cost-effective approaches for testing widely abused substances across all levels of sport, the following areas of investigation reflect the PCC's current research priorities: - Developing methods of cost-effective testing to detect and deter the use of banned and illegal substances. - Developing testing protocols to detect designer substances used for doping purposes. - Improving existing analytical methods to detect particular drugs, ex. GH, IGF-1, EPO, hCG. - Developing analytical methods to detect performance enhancing drugs not currently detectable. - Longitudinal urinary excretion patterns, metabolism and dose-concentration. - Critical reviews to support interpretation of laboratory data. - Alternative specimens, (ex. oral fluid, dried blood/plasma spots) for testing.

The PCC has supported world-class research since 2008, spending more than $18.0 M to support novel science around the world. Research and grant-making are the foundation of the PCC and are the focus of everyday business activity. PCC-supported research contributes to a movement in addressing doping's root causes and ultimately decreasing the use of performance-enhancing drugs by all participants in all sports at all levels of play. Grant Cycle Deadlines: Pre-Applications are due March 1st, July 1st, and November 1st of each year. Applicants invited to submit full applications must do so by April 1st, August 1st, or December 1st, depending on the cycle (30 days after the pre-application due date). With an emphasis on original work that focuses on improving existing analytical methods for detecting particular drugs, developing new analytical methods to test for substances not currently detectable, and discovering cost-effective approaches for testing widely abused substances across all levels of sport, the following areas of investigation reflect the PCC's current research priorities: Developing methods of cost-effective testing to detect and deter the use of banned and illegal substances. Developing testing protocols to detect designer substances used for doping purposes. Improving existing analytical methods to detect particular drugs, ex. GH, IGF-1, EPO, hCG. Developing analytical methods to detect performance enhancing drugs not currently detectable. Longitudinal urinary excretion patterns, metabolism and dose-concentration. Critical reviews to support interpretation of laboratory data. Alternative specimens, (ex. oral fluid, dried blood/plasma spots) for testing. There is no maximum amount for PCC funding, though the average funding amount is $225,000. To date, over 80 projects have been funded in over 14 countries world-wide. Approximately 33% of applicants are awarded PCC funding.

On September 13, WBI will be hosting its 3rd OEA Collider Event, this time on the topic of Human Performance Enhancement. Please block your calendars from 1:30 till 3:30 and plan to join us to learn more about the opportunities within this massive market space. For the purposes of this project, we're defining Human Performance Enhancement like this: As the world becomes more complex, the demands on human performance continue to increase. Athletic endeavors, military requirements, continuing independence into one's later years are all examples of market-driven needs for human performance enhancement. Strength, speed, endurance, vigilance, multi-tasking, mental-acuity, and recovery are all enhancement opportunities of interest. Formal evaluation of blue papers will begin on approximately 17 October 2016. Wright Brothers Institute continues to work diligently on our pilot project to refine a commercialization process for regional innovators. In March we had an OEA Collider event focused on the Precision Agriculture market which has resulted in 8 Blue Paper submissions and 2 on-going projects to commercialize several of the concepts explained in those blue papers. We're making significant progress toward providing real market solutions with a combination of several innovative technologies!

On September 13, WBI will be hosting its 3rd OEA Collider Event, this time on the topic of Human Performance Enhancement. Please block your calendars from 1:30 till 3:30 and plan to join us to learn more about the opportunities within this massive market space. For the purposes of this project, we're defining Human Performance Enhancement like this: As the world becomes more complex, the demands on human performance continue to increase. Athletic endeavors, military requirements, continuing independence into one's later years are all examples of market-driven needs for human performance enhancement. Strength, speed, endurance, vigilance, multi-tasking, mental-acuity, and recovery are all enhancement opportunities of interest. Formal evaluation of blue papers will begin on approximately 17 October 2016. Wright Brothers Institute continues to work diligently on our pilot project to refine a commercialization process for regional innovators. In March we had an OEA Collider event focused on the Precision Agriculture market which has resulted in 8 Blue Paper submissions and 2 on-going projects to commercialize several of the concepts explained in those blue papers. We're making significant progress toward providing real market solutions with a combination of several innovative technologies!

The University of South Alabama offers an interdisciplinary undergraduate research program sponsored by the National Science Foundation to work for 10 weeks over the summer semester in the area of "Structure and Function of Proteins".  Students accepted to the program must have a strong interest in basic research, and are expected to work full time in their projects under the direction of faculty advisors. Important Information Applicants must be US citizens or Permanent Residents (Green Card). Students must have completed one of the following courses or course sequences before the summer: Organic Chemistry sequence, Biochemistry sequence, Thermodynamics or Statics. All participants receive a stipend, free housing, food allowance and travel expenses. Minimum GPA of 3.0 or higher. Neither the University of South Alabama nor the National Science Foundation can provide health insurance to participants in the program. All participants are fully responsible for their own health insurance coverage. Accepted students are required to adhere to all policies of the University of South Alabama Student Handbook (The Lowdown) and Residence Life Handbook

The Shared Instrumentation for Animal Research (SIFAR) Grant Program encourages applications from groups of NIH-funded investigators to purchase or upgrade scientific instruments necessary to carry out animal experiments in all areas of biomedical research supported by the NIH. Applicants may request clusters of commercially available instruments configured as specialized integrated systems or as series of instruments to support a thematic well-defined area of research using animals or related materials. Priority will be given to uniquely configured systems to support innovative and potentially transformative investigations. This FOA supports requests for state-of-the art commercially available technologies needed for NIH-funded research using any vertebrate and invertebrate animal species. This funding opportunity announcement (FOA) does not support requests for single instruments. At least one item of the requested instrumentation must cost at least $50,000, after all applicable discounts. No instrument in a cluster can cost less than $20,000, after all applicable discounts. There is no maximum price requirement; however, the maximum award is $750,000.

The goal of this funding opportunity announcement (FOA) is to translate and adapt the most successful global, evidence-based HIV-related service provision strategies to marginalized populations in the United States (U.S.) with a substantial risk of HIV-infection and AIDS. The ultimate goal, is to produce improvements in HIV-related health outcomes in these key populations through strategies that successfully and durably reach them with timely HIV testing, prevention and treatment technologies that lead to the achievement of the UNAIDS 90-90-90 benchmarks: by 2020, 90 percent of all people living with HIV will know their HIV status, 90 percent of all people with diagnosed HIV infection will receive sustained antiretroviral therapy and 90 percent of all people receiving antiretroviral therapy will have viral suppression.

To foster innovative collaborative approaches to research projects that propose novel pairings of investigators from at least two broadly disparate disciplines. The proposal must focus on the collaborative relationship, such that the scientific objectives could not be achieved without the efforts of at least two co-principal investigators and their respective disciplines. The combination and integration of studies may be inclusive of basic, clinical, population, behavioral, and/or translational research. Projects must include at least one Co-PI from a field outside cardiovascular disease and stroke. This award is also intended to foster collaboration between established and early- or mid-career investigators. Applications by existing collaborators are permitted, provided that the proposal is for a new and novel idea or approach that has not been funded before. Multidisciplinary research broadly related to cardiovascular function, cardiovascular disease, and stroke, or to related clinical, basic science, bioengineering, biotechnology, or public health problems. Proposals are encouraged from all basic science disciplines as well as epidemiological, behavioral, community and clinical investigations that bear on cardiovascular and stroke problems. AHA awards are open to the array of academic and health professionals. This includes but is not limited to all academic disciplines (biology, chemistry, engineering, mathematics, technology, physics, etc.) and all health-related professions (physicians, nurses, advanced practice nurses, pharmacists, dentists, physical and occupational therapists, statisticians, nutritionists, behavioral scientists, health attorneys, engineers, etc.).

The NSF Division of Undergraduate Education (DUE) in collaboration with AAAS will offer an Improving Undergraduate STEM Education: Education and Human Resources (IUSE: EHR) webinar focusing on opportunities for funding in the IUSE: EHR program, specifically associated with expectations of the new IUSE solicitation, NSF 19-601. An audio archive and slides will be posted after the webinar at https://aaas-iuse.org. The IUSE: EHR program "seeks to promote novel, creative, and transformative approaches to generating and using new knowledge about STEM teaching and learning to improve STEM education for all undergraduates." The program supports proposals interested in improving undergraduate education, developing faculty expertise, preparing K-12 teachers, and providing all undergraduate students with STEM competencies and a basic understanding of STEM concepts and principles. All projects must contribute to the body of knowledge about what works in undergraduate STEM education and the conditions that lead to improved STEM teaching and learning. 

The NSF Division of Undergraduate Education (DUE) in collaboration with AAAS will offer an Improving Undergraduate STEM Education: Education and Human Resources (IUSE: EHR) webinar focusing on opportunities for funding in the IUSE: EHR program, specifically associated with the Institutional and Community Transformation (ICT) track of the IUSE program. An audio archive and slides will be posted after the webinar at https://aaas-iuse.org. The IUSE: EHR program "seeks to promote novel, creative, and transformative approaches to generating and using new knowledge about STEM teaching and learning to improve STEM education for all undergraduates." The program supports proposals interested in improving undergraduate education, developing faculty expertise, preparing K-12 teachers, and providing all undergraduate students with STEM competencies and a basic understanding of STEM concepts and principles. All projects must contribute to the body of knowledge about what works in undergraduate STEM education and the conditions that lead to improved STEM teaching and learning. The ICT track seeks to fund innovative work on systemic change that may be measured at the departmental, institutional, or multi-institutional level, or across communities of STEM educators and/or educational researchers. ICT projects are expected to include one or more theories of change to guide the proposed work and this webinar will provide information about expectations for Identifying and incorporating these theories of change.

July 16 | 3:00-4:30pm ET The IUSE: EHR program seeks to promote novel, creative, and transformative approaches to generating and using new knowledge about STEM teaching and learning to improve STEM education for all undergraduates. The program supports proposals interested in improving undergraduate education, developing faculty expertise, preparing K-12 teachers, and providing all undergraduate students with STEM competencies and a basic understanding of STEM concepts and principles. All projects must contribute to the body of knowledge about what works in undergraduate STEM education and the conditions that lead to improved STEM teaching and learning.

In 2020, we are offering a series of research grants to stimulate innovative research in challenging areas of future importance. Grants of 100,000 EUR - 500,000 EUR per year for up to 3 years are availabe in the areas of  - Drug discovery  - Bioreactor design for cultured meat - Next generation machine learning - Pandemic preparedness / fighting new emerging viral infectious disease The research grants program is open to scientists in all career stages who are affiliated with any research-based institution, university or company. Applicants submit their application for the focus topics containing non-confidential information only. You may apply for more than one focus topic. If your application is successful, you will be invited to submit a full proposal and join a deep-dive workshop with the other finalists in 2020.   Submissions are accepted from scientists in all countries all over the world. 

WHO CAN APPLY? I-Corps@Ohio funds will be offered on a competitive basis to teams of faculty researchers and graduate students developing institution-based technologies from Ohio colleges and universities. Under the supervision of business and entrepreneurial mentors, teams will develop market-driven value propositions and scalable business models around their technologies and attract follow on funding to support company formation and market entry. APPLICATION PROCESS The I-Corps@Ohio proposal submission process consists of five steps: 1. mandatory meeting with the appropriate TTO representative(s) at the PI's institution; 2. team selection of technology track (science and engineering or medtech); 3. registration of all team members in the online portal; 4. proposal submission; and 5. full team interview with I-Corps@Ohio program representatives. All teams are required to complete the online profile and submission questionnaire beginning October 23, 2019. Deadline to apply is January 15, 2019. The PI may complete this information or designate another member of the team as the lead member. Subsequent members of the team will be invited to join by the lead member through the application portal and must complete his or her profile. Every effort should be made to identify all team members prior to submitting the online proposal submission questionnaire. Additional team members may be added later. You will be asked to select from two tracks: Medtech Track: Teams will select Medtech Track if the subject technology is in the form of medical devices, diagnostics, medicines, vaccines, software, testing procedures and systems and is developed to solve a health/clinical problem and improve the quality of human life. Science and Engineering (S&E) Track: Teams will select S&E Track if the technology does not fit into the Medtech category.

This Funding Opportunity Announcement (FOA) intends to support a Brain Cell Data Center (BCDC) that will work with other BICCN Centers and interested researchers to establish a web-accessible information system to capture, store, analyze, curate, and display all data and metadata on brain cell types, and their connectivity. The BCDC is expected to: (1) lead the effort to establish spatial and semantic standards for managing heterogeneous brain cell census data types and information; (2) lead the effort to collect and register multimodal brain cell census data to common brain coordinate systems; (3) generate searchable 2D and 3D digital brain atlases for cell census data; and (4) generate a unified and comprehensive brain cell knowledge base that integrates all existing brain cell census data and information across diverse repositories.  A central goal of this and the three companion FOAs is to build a brain cell census resource that can be widely used throughout the research community.

The Agency for Healthcare Research and Quality's (AHRQ) mission is to produce evidence to make health care safer, higher quality, more accessible, equitable, and affordable, and to work within the U.S. Department of Health and Human Services and with other partners to make sure that the evidence is understood and used. AHRQ's Center for Quality Improvement and Patient Safety (CQuIPS) is addressing patient safety and medication research by focusing on the safe usage of medications.  This perspective centers on how medications move through the health care system and how this systemic process can be improved so that patients are not harmed, while health care delivery is improved.  CQuIPS encourages the involvement of all members of the health care team, especially patients and families, nurses, pharmacists, technicians (pharmacy and medication administration technicians), health care administrators, risk managers, and physicians across all settings of care, including in the home. This FOA will fund investigative research demonstration projects that examine the effective implementation of processes, policies, and behaviors that support safe use of medication as well as its sustainment and dissemination.

The Division of Integrative Organismal Systems (IOS) supports research aimed at understanding why organisms are structured the way they are and function as they do. Proposals should focus on organisms as a fundamental unit of biological organization. Principal Investigators (PIs) are encouraged to apply systems approaches that will lead to conceptual and theoretical insights and predictions about emergent organismal properties. Areas of inquiry include, but are not limited to, developmental biology and the evolution of developmental processes, nervous system development, structure, and function, physiological processes, functional morphology, symbioses, interactions of organisms with biotic and abiotic environments, and animal behavior. Proposals are welcomed in all areas of science supported by the Division of Integrative Organismal Systems. All investigator-initiated proposals to the core programs in the Division of Integrative Organismal Systems must now be invited based on merit review of preliminary proposals. 

Candidates must hold a Ph.D. (or equivalent) in chemistry, computational or evolutionary molecular biology, computer science, economics, mathematics, neuroscience, ocean sciences (including marine biology), physics, or a related field; Candidates must hold a tenure track (or equivalent) position at a college, university or other degree-granting institution in the United States or Canada;  Candidates must normally be no more than six years from completion of their most recent Ph.D. (or equivalent) as of the year of their nomination.  (That is, most recent Ph.D. must have been awarded on or after September 2007.)** While Fellows are expected to be at an early stage of their research careers, there should be strong evidence of independent research accomplishments. Candidates in all fields are normally below the rank of associate professor and do not hold tenure, but these are not strict requirements. The Alfred P. Sloan Foundation welcomes nominations of all candidates who meet the traditional high standards of this program, and strongly encourages the participation of women and members of underrepresented minority groups.

The Process and Reaction Engineering program supports fundamental and applied research on: Rates and mechanisms of important classes of catalyzed and uncatalyzed chemical reactions as they relate to the design, production, and application of catalysts, chemical processes, biochemical processes, and specialized materials Chemical and biochemical phenomena occurring at or near solid surfaces and interfaces Electrochemical and photochemical processes of engineering significance or with commercial potential Design and optimization of complex chemical and biochemical processes Dynamic modeling and control of process systems and individual process units Reactive processing of polymers, ceramics, and thin films Interactions between chemical reactions and transport processes in reactive systems, and the use of this information in the design of complex chemical and biochemical reactors  Recent emphasis on the development of sustainable energy technologies means that the support of projects on the processing aspects of chemical systems that further such technologies have high priority when funding decisions are made. Areas that focus on reactors of all types - fuel cells, batteries, microreactors, biochemical reactors, etc.; reactor design in general; and design and control of all systems associated with energy from renewable sources, have high priority for funding.

The Office of the Science Advisor (OSA), Office of Research and Development (ORD) at the U.S. Environmental Protection Agency (EPA) is seeking 1 individual, to interact with all of these councils  and forums, but primary focus will be to support the Council for Regulatory Environmental Modeling (CREM), Forum on Environmental Measurements (FEM), and Environmental Laboratory Advisory  Board (ELAB). The Office of the Science Advisor (OSA), led by the Agency Science Advisor and the Deputy Director, provides leadership in cross-Agency science and science policy development and implementation to  ensure the best possible use of science at the Agency. The OSA accomplishes this through the: Science and Technology Policy Council, Risk Assessment Forum, Program in Human Research Ethics, Forum  on Environmental Measurements, Environmental Laboratory Advisory Board, and Council for Regulatory Environmental Modeling.  The duty location is Research Triangle Park, North Carolina. Work is expected to begin in September or October, 2013 and have a one (1) year period. Two (2) additional one (1) year optional periods may  be exercised, depending on performance and need. The total duration of the order, including base and any option periods and other extension shall not exceed thirty six months or 3 years. The student  contractor will be paid by the hour for a maximum of 1928 hours annually. The total value of the order (base and all option periods) shall not exceed $150,000.00.

The National Institute on Drug Abuse (NIDA) will solicit proposals from qualified organizations capable of maintaining and expanding the NIDA Center for Genetic Studies. In this effort, the contractor will be required to: (1) Receive de-identified clinical, diagnostic, pedigree structure, environmental exposure information and other phenotypic data along with blood samples or other biospecimens from funded grants and/or contracts supporting research on the genetics of addiction and addiction vulnerability; (2) Process these data and materials to create databases, serum, DNA, RNA, and cell lines; (3) Widely distribute all data and materials in the NIDA Human Genetics Initiative to qualified investigators in the scientific community in a cost effective manner; (4) Maintain storage of data and biomaterials; (5) As stipulated by NIDA staff, perform microarray typing on pre-existing and/or new de-identified biospecimens; (6) As stipulated by NIDA staff, perform high-throughput sequencing on pre-existing and/or new de-identified biospecimens for genomic and/or epigenomic analyses; (7) Support the creation of reprogrammed cellular derivatives, such as induced pluripotent stem cells (iPSCs) to facilitate the molecular and cellular study of brain development and addiction processes; (8) Create a cyberinfrastructure that enables interoperability and full access to distributed data, software and other information science resources as well as research summaries and outbound links for all addiction related studies available through the NIH database of Genotype and Phenotype (dbGaP) system; and (9) Faciliate NIDA genetic studies data (both genotype and phenotype) being uploaded into NIH databases such as BioSample, and the dbGaP systems.