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To allow investigators time to plan and develop applications, the TSCRP is providing its strategic plan for award mechanisms to be offered in 2013 should funding become available. Congressional funds for the FY13 TSCRP have not yet been appropriated, and this document is not to be construed as an obligation by the government; there is no guarantee of funding for these planned mechanisms. Areas of Focus: The FY13 TSCRP encourages research projects applications that specifically address the critical needs of theTSC community in the following areas of focus: Genetic, epigenetic, and non-genetic modifiers of TSC. Identification and development of preclinical models and therapeutic strategies (e.g., cytotoxic agents, combination therapies). Identifying biomarkers for early detection, prognosis, and prediction of treatment outcomes (such as serum markers, imaging, electrophysiology, prenatal testing, and pharmacogenetics). Impact of TSC manifestations in adults (e.g., care management, age-specific pathogenesis, epidemiology, renal, reproductive issues, and lymphangioleiomyomatosis [LAM])). Long-term benefits and effects of mTOR inhibitors or other agents. Novel strategies for diagnosis, treatment, and prevention of TSC manifestations including those geared toward early identification and intervention. Understanding the cellular and molecular mechanisms of TSC and LAM pathogenesis. Understanding the mechanism and improving the treatment of epilepsy in TSC. Understanding the mechanism and improving treatment of TSC-associated neurocognitive disorders (TAND) including cognitive impairment, and psychiatric, behavioral, and sleep disorders.

The OR program supports fundamental research leading to the creation of innovative mathematical models, analysis, and algorithms for optimal or near optimal decision-making, applicable to the design and operation of manufacturing, service, and other complex systems. In addition to the traditional areas of Operations Research which includes discrete and continuous optimization as well as stochastic modeling and analysis, new research thrusts include simulation optimization and self-optimizing systems that can observe, learn, and adapt to changing environments.

This award is designed to support young scientists just embarking on their independent research careers.  The applicants' research interests should be consonant with those of the March of Dimes' mission: The  Mission of the March of Dimes is to improve the health of babies by preventing birth defects, premature birth and infant mortality. The March of Dimes defines a birth defect as any abnormality of structure or function, whether inherited, or acquired in utero and presenting in infancy or early childhood. Deviations from reproductive health of women and men as an underlying basis of birth defects, i.e. preconceptional events, perinatal course, and premature births, are appropriate subjects for research support. Relevance is interpreted broadly to include fundamental cell biology (embryogenesis, cell lineage, differentiation), genetics and genomics, fundamental cellular and clinical pathogenesis of disorders of importance to mothers and infants, biomedical engineering and imaging, and social and behavioral aspects. Each application should be accompanied by a Letter of Support from a Nominator (see below). The award is $150,000 for two years, including 10 percent indirect costs to sponsoring institutions.

Formerly the Behavioral Medicine & Psychology Interest Group Lectureship for Distinguished Contributions, the Richard R. Rubin Award Lecture is given in memory of Richard R.Rubin, PhD, CDE, a long time Association volunteer, who served as President, Health Care and Education, and chair of the Council on Behavioral Medicine & Psychology, and received numerous professional and service awards. Specifically, the Richard R. Rubin Award recognizes a behavioral researcher who has made outstanding and/or innovations contributions in the study and understanding of the behavioral aspects of diabetes.

Attention veterinarians, lab technicians, animal technicians, and all who work with laboratory animals: The Johns Hopkins Center for Alternatives to Animal Testing (CAAT) now is accepting proposals for the 2014 Science-based Refinement Awards (formerly the Animal Welfare Enhancement Awards). The focus of these awards is to elicit scientific evidence to support the enhancement of the housing, handling and/or experimental situations for laboratory animals. Studies may, for example, examine: how physiological and behavioral stress responses to common husbandry (e.g., capture) and traditional treatment procedures (e.g., gavage, injection, blood collection) can be reduced or eliminated (e.g., by training the subjects to cooperate rather than resist); whether animals caged at different tier levels show different physiological and behavioral stress responses when being approached by personnel, and how these responses can be minimized or avoided; whether the presence of a compatible companion buffers physiological and behavioral stress responses to experimental situations (e.g., enforced restraint); whether animals kept in legally minimum-sized cages benefit from a moderate increase in space that is (a) empty versus (b) structured in species-appropriate ways (e.g., shelter, visual blind, perch, platform, PVC tube).

The Division of Integrative Organismal Systems (IOS) supports research aimed at understanding why organisms are structured the way they are and function as they do. Proposals should focus on organisms as a fundamental unit of biological organization. Principal Investigators (PIs) are encouraged to apply systems approaches that will lead to conceptual and theoretical insights and predictions about emergent organismal properties. Areas of inquiry include, but are not limited to, developmental biology and the evolution of developmental processes, nervous system development, structure, and function, physiological processes, functional morphology, symbioses, interactions of organisms with biotic and abiotic environments, and animal behavior.

Cyberspace has transformed the daily lives of people for the better. The rush to adopt cyberspace, however, has exposed its fragility and vulnerabilities: corporations, agencies, national infrastructure and individuals have been victims of cyber-attacks. In December 2011, the National Science and Technology Council with the cooperation of NSF has advanced a broad, coordinated federal strategic plan for cybersecurity research and development to "change the game," check the misuses of cyber technology, bolster education and training in cybersecurity, establish a science of cybersecurity, and transition promising cybersecurity research into practice.  This challenge requires a dedicated approach to research, development, and education that leverages the disciplines of mathematics and statistics, the social sciences, and engineering with the computational and information sciences.

The Army Research Institute for the Behavioral and Social Sciences is the Army's lead agency for the conduct of research, development, and analyses for the improvement of Army readiness and performance via research advances and applications of the behavioral and social sciences that address personnel, organization, training, and leader development issues. ARI contracts with educational institutions, nonprofit organizations, and private industry for research and development (R&D) in different areas, including the areas specifically identified in Part I of BAA W911NF-13-R-0001. The ARI Basic Research Program supports research projects that are designed to expand fundamental knowledge and discover general principles in the behavioral and social sciences. Efforts funded under this White Paper request will only include Basic Research.

Recognizing disciplinary differences and priorities, NSF's investment in research and development in undergraduate STEM education encompasses a range of approaches. These approaches include: experiential learning, assessment/metrics of learning and practice, scholarships, foundational education research, professional development/institutional change, formal and informal learning environments, and undergraduate disciplinary research. Both individually and integrated in a range of combinations, these approaches can lead to outcomes including: developing the STEM and STEM-related workforce, advancing science, broadening participation in STEM, educating a STEM-literate populace, improving K-12 STEM education, encouraging life-long learning, and building capacity in higher education.

The Richard Kalish Innovative Publication Award recognizes insightful and innovative publications on aging and life course development in the behavioral and social sciences. Any empirical or conceptual publication which represents state-of-the-art thinking in aging and life course development is eligible for the award provided it is in English and was published in the last three years. Two $250 awards (one for an article and one for a book) are underwritten by Baywood Publishing Company, with whom Dr. Kalish was long associated.

This two-day conference focuses on translational aspects of addiction research among chemists, biologists, and behavioral scientists. The diversity of participants and attendees at this meeting (undergraduate students to senior faculty, chemists to psychiatrists) provides a unique venue for cross-fertilization among different disciplines and in so doing promotes new and innovative approaches to medications development in addictions biology. The meeting provides a stimulating environment for young scientists who are strongly encouraged to present their work and interact with senior scientists.

The Social Psychology Program at NSF supports basic research on human social behavior, including cultural differences and development over the life span.  Among the many research topics supported are: attitude formation and change, social cognition, personality processes, interpersonal relations and group processes, the self, emotion, social comparison and social influence, and the psychophysiological and neurophysiological bases of social behavior.  The scientific merit of a proposal depends on four important factors: (1) The problems investigated must be theoretically grounded. (2) The research should be based on empirical observation or be subject to empirical validation. (3) The research design must be appropriate to the questions asked. (4) The proposed research must advance basic understanding of social behavior.

As part of NSF's Cyberinfrastructure Framework for 21st Century Science and Engineering (CIF21) activity, the Directorate for Social, Behavioral and Economic Sciences (SBE) seeks to develop user-friendly large-scale next-generation data resources and relevant analytic techniques to advance fundamental research in SBE areas of study. Successful proposals will, within the financial resources provided by the award, construct such databases and/or relevant analytic techniques and produce a finished product that will enable new types of data-intensive research. The databases or techniques should have significant impacts, either across multiple fields or within broad disciplinary areas, by enabling new types of data-intensive research in the SBE sciences.

The goals of the Resilient Interdependent Infrastructure Processes and Systems (RIPS) solicitation are (1) to foster an interdisciplinary research community that discovers new knowledge for the design and operation of infrastructures as processes and services  (2) to enhance the understanding and design of interdependent critical infrastructure systems (ICIs) and processes that provide essential goods and services despite disruptions and failures from any cause, natural, technological, or malicious, and (3) to create the knowledge for innovation in ICIs to advance society with new goods and services. The objectives of this solicitation are: Create theoretical frameworks and multidisciplinary computational models of interdependent infrastructure systems, processes and services, capable of analytical prediction of complex behaviors, in response to system and policy changes. Synthesize new approaches to increase resilience, interoperations, performance, and readiness in ICIs. Understand organizational, social, psychological, legal, political and economic obstacles to improving ICI's, and identifying strategies for overcoming those obstacles. The RIPS solicitation seeks proposals with transformative ideas that will ensure ICIs services are effective, efficient, dependable, adaptable, resilient, safe, and secure.  Successful proposals are expected to study multiple infrastructures focusing on them as interdependent systems that deliver services, enabling a new interdisciplinary paradigm in infrastructure research.  Proposals that do not broadly integrate across the cyber-physical, engineering and social, behavioral and economic (SBE) sciences may be returned without review. 

Pathway supports innovative basic, clinical, translational, epidemiological, behavioral, or health services research relevant to any diabetes type, diabetes-related disease state, or diabetes complication. The Association seeks exceptional candidates from a broad range of disciplines, including medicine, biology, chemistry, computing, physics, mathematics and engineering.

The Interdisciplinary Behavioral and Social Science Research (IBSS) competition promotes the conduct of interdisciplinary research by teams of investigators in the social and behavioral sciences.  Emphasis is placed on support for research that involves researchers from multiple disciplinary fields, that integrates scientific theoretical approaches and methodologies from multiple disciplinary fields, and that is likely to yield generalizable insights and information that will advance basic knowledge and capabilities across multiple disciplinary fields.

The United Mitochondrial Disease Foundation (UMDF) is committed to facilitating the development of treatments and cures for mitochondrial disease and recognizes that research, from benchtop to bedside, is the path to success. The sponsor also recognizes that there is often a gap in the funding of research projects for rare disorders. They seek to fund high potential impact projects that will forward the cause of improving the lives of those affected by mitochondrial disease.  

The program's goals are to support psychology's efforts to improve areas of critical need in society, including but not limited to innovative scientifically based clinical work with serious mental illness, serious emotional disturbance, incarcerated or homeless individuals, children with serious emotional disturbance (SED) and adults with serious mental illness (SMI); and to encourage early career psychologists to devote their careers to under-served populations.

This year, as part of our impact initiative, we will be asking applicants to consider impact from the onset. SFPRF defines impact as the demonstrable contribution that family planning research makes to society. This includes impact on clinical practice, public policy, health services, programs, or culture. Research projects should have the potential to exert influence through policies or practices that enhance family planning, including contraception and abortion. When addressing impact, consider who could potentially benefit from your work, as well as ways to increase the chances that those potential benefits will reach the target audience.

This year, as part of our impact initiative, we will be asking applicants to consider impact from the onset. SFPRF defines impact as the demonstrable contribution that family planning research makes to society. This includes impact on clinical practice, public policy, health services, programs, or culture. Research projects should have the potential to exert influence through policies or practices that enhance family planning, including contraception and abortion. When addressing impact, consider who could potentially benefit from your work, as well as ways to increase the chances that those potential benefits will reach the target audience.

The Cognitive Neuroscience Program seeks highly innovative and interdisciplinary proposals aimed at advancing a rigorous understanding of how the human brain supports thought, perception, affect, action, social processes, and other aspects of cognition and behavior, including how such processes develop and change in the brain and through time.