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The Civil Infrastructure Systems (CIS) program supports research leading to the engineering of infrastructure systems for resilience and sustainability without excluding other key performance issues. Areas of interest include intra- and inter-physical, information and behavioral dependencies of infrastructure systems, infrastructure management, construction engineering, and transportation systems. Special emphasis is on the design, construction, operation, and improvement of infrastructure networks with a focus on systems engineering and design, performance management, risk analysis, life-cycle analysis, modeling and simulation, behavioral and social considerations not excluding other methodological areas or the integration of methods.This program does not encourage research proposals primarily focused on structural engineering, materials or sensors that support infrastructure system design, extreme event modeling, hydrological engineering, and climate modeling, since they do not fall within the scope of the CIS program. Researchers focused in these areas are encouraged to contact the Infrastructure Management and Extreme Events (IMEE), Geotechnical Engineering (GTE), Hazard Mitigation and Structural Engineering (HSME), Structural Materials and Mechanics (SMM), or the Sensors and Sensing Systems (SSS) program within CMMI. Additionally, researchers may consider contacting the Hydrologic Sciences program in the Earth Sciences Division (EAR) or the Physical and Dynamic Meteorology (PDM) program in the Atmospheric and Geospace Sciences Division (AGS) of the Directorate for Geosciences.

Critical infrastructures are the mainstay of our nation's economy, security and health. These infrastructures are interdependent. They are linked to individual preferences and community needs. For example, the electrical power system depends on the delivery of fuels to power generating stations through transportation services, the production of those fuels depends in turn on the use of electrical power, and those fuels are needed by the transportation services. Social networks, interactions, and policies can enable or hinder the successful creation of resilient complex adaptive systems. The goals of the Critical Resilient Interdependent Infrastructure Systems and Processes (CRISP) solicitation are to: (1) foster an interdisciplinary research community of engineers, computer and computational scientists and social and behavioral scientists, that creates new approaches and engineering solutions for the design and operation of infrastructures as processes and services; (2) enhance the understanding and design of interdependent critical infrastructure systems (ICIs) and processes that provide essential goods and services despite disruptions and failures from any cause, natural, technological, or malicious; (3) create the knowledge for innovation in ICIs so that they safely, securely, and effectively expand the range of goods and services they enable; and (4) improve the effectiveness and efficiency with which they deliver existing goods and services.

Critical infrastructures are the mainstay of our nation's economy, security and health. These infrastructures are interdependent. They are linked to individual preferences and community needs. For example, the electrical power system depends on the delivery of fuels to power generating stations through transportation services, the production of those fuels depends in turn on the use of electrical power, and those fuels are needed by the transportation services. Social networks, interactions, and policies can enable or hinder the successful creation of resilient complex adaptive systems. The goals of the Critical Resilient Interdependent Infrastructure Systems and Processes (CRISP) solicitation are to: (1) foster an interdisciplinary research community of engineers, computer and computational scientists and social and behavioral scientists, that creates new approaches and engineering solutions for the design and operation of infrastructures as processes and services; (2) enhance the understanding and design of interdependent critical infrastructure systems (ICIs) and processes that provide essential goods and services despite disruptions and failures from any cause, natural, technological, or malicious; (3) create the knowledge for innovation in ICIs so that they safely, securely, and effectively expand the range of goods and services they enable; and (4) improve the effectiveness and efficiency with which they deliver existing goods and services.

The goals of the Resilient Interdependent Infrastructure Processes and Systems (RIPS) solicitation are (1) to foster an interdisciplinary research community that discovers new knowledge for the design and operation of infrastructures as processes and services  (2) to enhance the understanding and design of interdependent critical infrastructure systems (ICIs) and processes that provide essential goods and services despite disruptions and failures from any cause, natural, technological, or malicious, and (3) to create the knowledge for innovation in ICIs to advance society with new goods and services. The objectives of this solicitation are: Create theoretical frameworks and multidisciplinary computational models of interdependent infrastructure systems, processes and services, capable of analytical prediction of complex behaviors, in response to system and policy changes. Synthesize new approaches to increase resilience, interoperations, performance, and readiness in ICIs. Understand organizational, social, psychological, legal, political and economic obstacles to improving ICI's, and identifying strategies for overcoming those obstacles. The RIPS solicitation seeks proposals with transformative ideas that will ensure ICIs services are effective, efficient, dependable, adaptable, resilient, safe, and secure.  Successful proposals are expected to study multiple infrastructures focusing on them as interdependent systems that deliver services, enabling a new interdisciplinary paradigm in infrastructure research.  Proposals that do not broadly integrate across the cyber-physical, engineering and social, behavioral and economic (SBE) sciences may be returned without review. 

The NSF ADVANCE program provides grants to enhance the systemic factors that support equity and inclusion and to mitigate the systemic factors that create inequities in the academic profession and workplaces. Systemic (or organizational) inequities may exist in areas such as policy and practice as well as in organizational culture and climate. For example, practices in academic departments that result in the inequitable allocation of service or teaching assignments may impede research productivity, delay advancement, and create a culture of differential treatment and rewards. Similarly, policies and procedures that do not mitigate implicit bias in hiring, tenure, and promotion decisions could lead to women and racial and ethnic minorities being evaluated less favorably, perpetuating historical under-participation in STEM academic careers and contributing to an academic climate that is not inclusive. All NSF ADVANCE proposals are expected to use intersectional approaches in the design of systemic change strategies in recognition that gender, race and ethnicity do not exist in isolation from each other and from other categories of social identity. The solicitation includes four funding tracks: Institutional Transformation (IT), Adaptation, Partnership, and Catalyst, in support of the NSF ADVANCE program goal to broaden the implementation of systemic strategies that promote equity for STEM faculty in academic workplaces and the academic profession.

The goal of the Smart and Connected Health (SCH) Program is to accelerate the development and use of innovative approaches that would support the much needed transformation of healthcare from reactive and hospital-centered to preventive, proactive, evidence-based, person-centered and focused on well-being rather than disease. Approaches that partner technology-based solutions with biobehavioral health research are supported by multiple agencies of the federal government including the National Science Foundation (NSF) and the National Institutes of Health (NIH). The purpose of this program is to develop next generation health care solutions and encourage existing and new research communities to focus on breakthrough ideas in a variety of areas of value to health, such as sensor technology, networking, information and machine learning technology, decision support systems, modeling of behavioral and cognitive processes, as well as system and process modeling. Effective solutions must satisfy a multitude of constraints arising from clinical/medical needs, social interactions, cognitive limitations, barriers to behavioral change, heterogeneity of data, semantic mismatch and limitations of current cyberphysical systems. Such solutions demand multidisciplinary teams ready to address technical, behavioral and clinical issues ranging from fundamental science to clinical practice.

The goal of the Smart and Connected Health (SCH) Program is to accelerate the development and use of innovative approaches that would support the much needed transformation of healthcare from reactive and hospital-centered to preventive, proactive, evidence-based, person-centered and focused on well-being rather than disease. Approaches that partner technology-based solutions with biobehavioral health research are supported by multiple agencies of the federal government including the National Science Foundation (NSF) and the National Institutes of Health (NIH). The purpose of this program is to develop next generation health care solutions and encourage existing and new research communities to focus on breakthrough ideas in a variety of areas of value to health, such as sensor technology, networking, information and machine learning technology, decision support systems, modeling of behavioral and cognitive processes, as well as system and process modeling. Effective solutions must satisfy a multitude of constraints arising from clinical/medical needs, social interactions, cognitive limitations, barriers to behavioral change, heterogeneity of data, semantic mismatch and limitations of current cyberphysical systems. Such solutions demand multidisciplinary teams ready to address technical, behavioral and clinical issues ranging from fundamental science to clinical practice.

The Division of Integrative Organismal Systems (IOS) supports research aimed at understanding why organisms are structured the way they are and function as they do. Proposals should focus on organisms as a fundamental unit of biological organization. Principal Investigators (PIs) are encouraged to apply systems approaches that will lead to conceptual and theoretical insights and predictions about emergent organismal properties. Areas of inquiry include, but are not limited to, developmental biology and the evolution of developmental processes, nervous system development, structure, and function, physiological processes, functional morphology, symbioses, interactions of organisms with biotic and abiotic environments, and animal behavior.

The CRISP solicitation seeks to fund projects likely to produce new knowledge that can contribute to making ICI services more effective, efficient, dependable, adaptable, resilient, safe, and secure, taking into account the human systems in which they are embedded. Successful proposals are expected to study multiple infrastructures focusing on them as interdependent systems that deliver services, enabling a new interdisciplinary paradigm in infrastructure research. To meet the interdisciplinary criterion, proposals must broadly integrate across engineering, computer, information and computational science, and the social, behavioral and economic sciences.

The CRISP solicitation seeks to fund projects likely to produce new knowledge that can contribute to making ICI services more effective, efficient, dependable, adaptable, resilient, safe, and secure, taking into account the human systems in which they are embedded. Successful proposals are expected to study multiple infrastructures focusing on them as interdependent systems that deliver services, enabling a new interdisciplinary paradigm in infrastructure research. To meet the interdisciplinary criterion, proposals must broadly integrate across engineering, computer, information and computational science, and the social, behavioral and economic sciences.

The goal of the Smart and Connected Health (SCH) Program is to accelerate the development and use of innovative approaches that would support the much needed transformation of healthcare from reactive and hospital-centered to preventive, proactive, evidence-based, person-centered and focused on well-being rather than disease. Approaches that partner technology-based solutions with biobehavioral health research are supported by multiple agencies of the federal government including the National Science Foundation (NSF) and the National Institutes of Health (NIH). The purpose of this program is to develop next generation health care solutions and encourage existing and new research communities to focus on breakthrough ideas in a variety of areas of value to health, such as sensor technology, networking, information and machine learning technology, decision support systems, modeling of behavioral and cognitive processes, as well as system and process modeling. Effective solutions must satisfy a multitude of constraints arising from clinical/medical needs, social interactions, cognitive limitations, barriers to behavioral change, heterogeneity of data, semantic mismatch and limitations of current cyberphysical systems. Such solutions demand multidisciplinary teams ready to address technical, behavioral and clinical issues ranging from fundamental science to clinical practice.

A sustainable world is one in which human needs are met equitably and without sacrificing the ability of future generations to meet their needs.  Meeting this formidable challenge requires a substantial increase in our understanding of the integrated system of society, the natural world, and the alterations humans bring to Earth.  NSF's Science, Engineering, and Education for Sustainability (SEES) activities aim to address this need through support for interdisciplinary research and education. Coastal SEES is focused on the sustainability of coastal systems.  For this solicitation we define coastal systems as the swath of land closely connected to the sea, including barrier islands, wetlands, mudflats, beaches, estuaries, cities, towns, recreational areas, and maritime facilities; the continental seas and shelves; and the overlying atmosphere.

The Partnerships for Innovation: Building Innovation Capacity (PFI:BIC) program supports academe-industry partnerships which are led by an interdisciplinary academic research team collaborating with a least one industry partner. In this program, there is a heavy emphasis on the quality, composition, and participation of the partners, including the appropriate contributions for each role. These partnerships focus on the integration of technologies into a specified human-centered service system with the potential to achieve transformational change, satisfying a real need by making an existing service system smart(er) or by spurring the creation of an entirely new smart service system.

Cyberspace has transformed the daily lives of people. Society's overwhelming reliance on cyberspace, however, has exposed its fragility and vulnerabilities: corporations, agencies, national infrastructure and individuals continue to suffer cyber-attacks. Achieving a truly secure cyberspace requires addressing both challenging scientific and engineering problems involving many components of a system, and vulnerabilities that stem from human behaviors and choices. Examining the fundamentals of security and privacy as a multidisciplinary subject can lead to fundamentally new ways to design, build and operate cyber systems, protect existing infrastructure, and motivate and educate individuals about cybersecurity. The Cybersecurity Enhancement Act of 2014,as amended by the National Defense Authorization Act for FY 2018, authorizes the National Science Foundation, in coordination with the Office of Personnel Management and the Department of Homeland Security, to offer a scholarship program to recruit and train the next generation of information technology professionals, industry control system security professionals and security managers to meet the needs of the cybersecurity mission for federal, state, local, and tribal governments. The goals of the CyberCorps(R): Scholarship for Service (SFS) program are aligned with the U.S. National Cyber Strategy to develop a superior cybersecurity workforce. The SFS program welcomes proposals to establish or to continue scholarship programs in cybersecurity. All scholarship recipients must work after graduation for a federal, state, local, or tribal Government organization in a position related to cybersecurity for a period equal to the length of the scholarship. A proposing institution must provide clearly documented evidence of a strong existing academic program in cybersecurity.

NOAA's Office of Weather and Air Quality (OWAQ) is soliciting proposals for weather, air quality, and earth-system modeling research reflecting multiple science objectives spanning time scales from hours to seasons, and from weather and water observations and earth system modeling to social and behavioral science. There will be three grant competitions from this notification valued at approximately $7,000,000 as follows: 1) Joint Technology Transfer Initiative (JTTI), 2) Verification of the Origins of Rotation in Tornadoes Experiment - Southeast U.S. (VORTEX-SE), and 3) Climate Testbed (CTB). In alignment with the Weather Forecasting and Innovation Act of 2017 (Public Law 115-25), the funded projects should improve NOAA's understanding and ultimately its services of weather and water forecasting through engagement with the external scientific community on key science gaps of mutual interest. Through this funding opportunity, NOAA will support new weather, water, climate, earth system, and air quality observing and forecasting applications, including improved analysis techniques, better statistical or dynamic forecast models and techniques, and communication of that information to better inform the public.

The multi-agency Ecology and Evolution of Infectious Diseases program supports research on the ecological, evolutionary, and social drivers that influence the transmission dynamics of infectious diseases. The central theme of submitted projects must be the quantitative or computational understanding of pathogen transmission dynamics. The intent is discovery of principles of infectious disease transmission and testing mathematical or computational models that elucidate infectious disease systems. Projects should be broad, interdisciplinary efforts that go beyond the scope of typical studies. They should focus on the determinants and interactions of transmission among humans, non-human animals, and/or plants. This includes, for example, the spread of pathogens; the influence of environmental factors such as climate; the population dynamics and genetics of reservoir species or hosts; the feedback between ecological transmission and evolutionary dynamics; and the cultural, social, behavioral, and economic dimensions of pathogen transmission. Research may be on zoonotic, environmentally-borne, vector-borne, or enteric pathogens of either terrestrial or aquatic systems and organisms, including diseases of animals and plants, at any scale from specific pathogens to inclusive environmental systems.

This Funding Opportunity Announcement (FOA) encourages Exploratory/Developmental Research Grant Award (R21) applications to study molecular and cellular mechanisms of tissue injury and repair associated with alcohol use in humans. Excessive alcohol consumption has the potential to adversely affect multiple organ systems including the liver, brain, heart, pancreas, lung, kidney, endocrine and immune systems, as well as bone and skeletal muscle. In addition, there is accumulating evidence that long term alcohol consumption is associated with reduced host capacity for recovery and repair following trauma. The mechanisms for these alcohol-induced effects on tissue injury and repair are currently not fully understood. NIAAA is especially interested in integrative research that elucidates alcohol's effects on complex mechanisms of injury and repair that are either common or specific to each organ system. This FOA also encourages the study of alcohol's effect on stem cells, embryonic development, and regeneration. Also encourages are studies on molecular and cellular actions of moderate alcohol consumption. A better understanding of these underlying mechanisms may provide new avenues for developing more effective and novel approaches for prognosis, diagnosis, intervention, and treatment of alcohol-induced organ damage.

This Funding Opportunity Announcement (FOA) will support pilot, feasibility or exploratory research in 5 priority areas in substance use epidemiology and health services, including: 1) responses to sudden and severe emerging drug issues (e.g. the ability to look into a large and sudden spike in synthetic cannabinoid use/overdoses in a particular community); 2) responses to emerging marijuana trends and topics related to the shifting policy landscape; 3) responses to unexpected and time-sensitive prescription drug abuse research opportunities (e.g.,new state or local efforts); 4) responses to unexpected and time-sensitive medical system issues (e.g. opportunities to understand addiction services in the evolving health care system); and 5) responses to unexpected and time-sensitive criminal or juvenile justice opportunities (e.g. new system and/or structural level changes) that relate to drug abuse and access and provision of health care service. It should be clear that the knowledge gained from the proposed study is time-sensitive and that an expedited rapid review and funding are required in order for the scientific question to be answered.

The Understanding the Rules of Life: Microbiome Theory and Mechanisms (URoL:MTM) program is an integrative collaborationacross Directorates and Offices within the National Science Foundation. The objective of URoL:MTM is to understand and establish the theory and mechanisms that govern the structure and function of microbiomes, a collection of microbes in a specific habitat/environment. This may include but is not limited to host-associated microbiomes, such as those with humans and other organisms, where i) the microbiome impacts host physiology, behavior, development, and fitness; ii) the host influences the metabolic activity, dynamics and evolution of the microbiome, and iii) the environment (biological, chemical, physical, and social) influences and is influenced by both the host and the microbiome. Recent progress has transformed our ability to identify and catalogue the microbes present in a given environment and measure multiple aspects ofbiological, chemical, physical, and social environments that affect the interactions among the members of the microbiome, the host, and/or habitat. Much descriptive and correlative work has been performed on many microbiome systems, particularly those in the human, soil, aquatic, and built environments. This research has resulted in new hypotheses about the microbiome's contributions to potential system function or dysfunction. The current challenge is to integrate the wide range of accumulated data and information and build on them to develop new causal/mechanistic models or theories of interactions and interdependencies across scales and systems.

The goal of the Smart and Connected Health (SCH) Program is to accelerate the development and use of innovative approaches that would support the much needed transformation of healthcare from reactive and hospital-centered to preventive, proactive, evidence-based, person-centered and focused on well-being rather than disease. Approaches that partner technology-based solutions with biobehavioral health research are supported by multiple agencies of the federal government including the National Science Foundation (NSF) and the National Institutes of Health (NIH). The purpose of this program is to develop next generation health care solutions and encourage existing and new research communities to focus on breakthrough ideas in a variety of areas of value to health, such as sensor technology, networking, information and machine learning technology, decision support systems, modeling of behavioral and cognitive processes, as well as system and process modeling.

The goals of the Critical Resilient Interdependent Infrastructure Systems and Processes (CRISP) solicitation are to: (1) foster an interdisciplinary research community of engineers, computer and computational scientists and social and behavioral scientists, that creates new approaches and engineering solutions for the design and operation of infrastructures as processes and services; (2) enhance the understanding and design of interdependent critical infrastructure systems (ICIs) and processes that provide essential goods and services despite disruptions and failures from any cause, natural, technological, or malicious; (3) create the knowledge for innovation in ICIs so that they safely, securely, and effectively expand the range of goods and services they enable; and (4) improve the effectiveness and efficiency with which they deliver existing goods and services.

The OR program supports fundamental research leading to the creation of innovative mathematical models, analysis, and algorithms for optimal or near optimal decision-making, applicable to the design and operation of manufacturing, service, and other complex systems. In addition to the traditional areas of Operations Research which includes discrete and continuous optimization as well as stochastic modeling and analysis, new research thrusts include simulation optimization and self-optimizing systems that can observe, learn, and adapt to changing environments.

The HHPR Summit is an international meeting supporting human systems research held in Dayton, Ohio with the objective of linking defense and academic research to the commercial domains. The Summit is a forum to generate research knowledge and ideas, recruit and retain key organizations and researchers in the human systems domain, and link research to entrepreneurial outcomes, and diffuse information.