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The F.J. McGuigan Dissertation Award provides support for dissertation research oriented toward advancing a unified conception of brain and behavior, primarily - but not exclusively - in the psychophysiological area. Deadline: June 1, 2014 Sponsor APF

This Funding Opportunity Announcement (FOA) aims to stimulate the broader research community to utilize a resource funded through the American Recovery and Reinvestment Act of 2009 (Recovery Act) to generate and evaluate hypotheses about the complex interrelationships and multi-directional influences among genetics, brain maturation, neurocognitive function, and psychiatric symptoms during development. This FOA is a strategic effort to disseminate this data resource, stimulate the broader research community to use the resource, and accelerate research on neurodevelopment and trajectories of risk for mental illness. Secondary goals of this initiative are to foster collaborations among researchers from diverse fields of expertise, enhance diversity of research questions and analytic approaches, advance methods for integration across data modalities and levels of analyses (i.e., imaging, genomics, behavior), and encourage inclusion of early stage investigators among these collaborations.

This Funding Opportunity Announcement (FOA) invites applications for Silvio O. Conte Centers for Basic or Translational Mental Health Research. The institute seeks teams of researchers working at different levels of analysis and employing integrative, novel, and creative experimental approaches to address high-risk, high-impact questions with the primary objective of: (a) advancing the state of the science in brain and behavior research that will ultimately provide the foundation for understanding mental disorders; (b) supporting the integration and translation of basic and clinical neuroscience research on severe mental illnesses; and/or (c) advancing our understanding of the neurobehavioral developmental mechanisms and trajectories of psychopathology that begin in childhood and adolescence. The Conte Centers program is intended to support interdisciplinary basic and/or translational research demonstrating an extraordinary level of synergy, integration, and potential for advancing the state of the field. This program is intended only for projects that could not be achieved using other, more standard grant mechanisms. The Conte Centers program also provides an opportunity to establish interdisciplinary basic and/or translational research experiences for individuals in training.  

This FOA solicits applications for research projects that use innovative and methodologically-integrated approaches to understand how circuit activity gives rise to mental experience and behavior. The goal is to support projects that can realize a meaningful outcome within 5 years. Applications should address circuit function in the context of specific neural systems such as sensation, perception, attention, reasoning, intention, decision-making, emotion, navigation, communication, or homeostasis. Projects should link theory and data analysis to experimental design and should produce predictive models as deliverables. Projects should aim to improve the understanding of circuits of the central nervous system by systematically controlling stimuli and/or behavior while actively recording and/or manipulating dynamic patterns of neural activity. Projects can use non-human animal species, and applications should explain how the selected species offers ideal conditions for revealing general principles about the circuit basis of a specific behavior.

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) invites applications to evaluate the cumulative and progressive effects on brain structure and cognitive/behavioral function of combined HIV infection and alcohol abuse on older patients cohorts.

This FOA solicits applications for research projects that use innovative, methodologically-integrated approaches to understand how circuit activity gives rise to mental experience and behavior. The goal is to support projects that can realize a meaningful outcome within 5 years. Applications should address circuit function in the context of specific neural systems such as sensation, perception, attention, reasoning, intention, decision-making, emotion, navigation, communication or homeostasis. Projects should link theory and data analysis to experimental design and should produce predictive models as deliverables. Projects should aim to improve the understanding of circuits of the central nervous system by systematically controlling stimuli and/or behavior while actively recording and/or manipulating dynamic patterns of neural activity. Projects can use non-human and human species, and applications should explain how the selected species offers ideal conditions for revealing general principles about the circuit basis of a specific behavior.

This FOA solicits applications for research projects that use innovative, methodologically-integrated approaches to understand how circuit activity gives rise to mental experience and behavior. The goal is to support projects that can realize a meaningful outcome within 5 years. Applications should address circuit function in the context of specific neural systems such as sensation, perception, attention, reasoning, intention, decision-making, emotion, navigation, communication or homeostasis. Projects should link theory and data analysis to experimental design and should produce predictive models as deliverables. Projects should aim to improve the understanding of circuits of the central nervous system by systematically controlling stimuli and/or behavior while actively recording and/or manipulating dynamic patterns of neural activity. Projects can use non-human and human species, and applications should explain how the selected species offers ideal conditions for revealing general principles about the circuit basis of a specific behavior.

CIFAR invites exceptional early career researchers to join CIFAR's global network of 370 researchers from 18 countries who together are pursuing answers to some of the most complex challenges facing the world today. The CIFAR Azrieli Global Scholars program provides funding, skills training, mentorship, and opportunities to collaborate with outstanding colleagues from diverse disciplines to position scholars as leaders and agents of change within academia and beyond. CIFAR Azrieli Global Scholars receive: * $100,000 CDN in unrestricted research support * A two-year membership to a CIFAR research program, with outstanding research leaders from across disciplines. Learn what it's like to be a CIFAR Fellow * Specialized leadership and communication skills training Applicants can be from anywhere in the world, must hold a PhD (or equivalent) and be within the first five years of a full-time academic appointment. Please note that postdoctoral fellows are not eligible to apply to the program. Scholars' research interests must be aligned with the themes of an eligible CIFAR research program.  In 2018, the eligible programs are: * Azrieli Program in Brain, Mind & Consciousness * Bio-Inspired Solar Energy * Gravity & the Extreme Universe * Humans & the Microbiome * Molecular Architecture of Life

The ASADRP is seeking applications to explore integrated approaches to address alcohol and substance use disorders (ASUD), especially related to traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD), through multidisciplinary, team-based research efforts that translate basic knowledge into enhanced clinical pharmacological treatment protocols. The program's goal is to organize multidisciplinary, team-based translational research efforts to: Identify promising compounds; Conduct proof-of-principle basic research to determine which compounds are most appropriate for human research trials; Conduct human proof-of-concept trials with promising compounds.

The ASADRP is seeking applications to explore integrated approaches to address alcohol and substance use disorders (ASUD), especially related to traumatic brain injury (TBI) and post-traumatic stress disorder (PTSD), through multidisciplinary, team-based research efforts that translate basic knowledge into enhanced clinical pharmacological treatment protocols. The program's goal is to organize multidisciplinary, team-based translational research efforts to: Identify promising compounds; Conduct proof-of-principle basic research to determine which compounds are most appropriate for human research trials; Conduct human proof-of-concept trials with promising compounds.

The program supports research addressing learning in individuals and in groups, across a wide range of domains at one or more levels of analysis including: molecular/cellular mechanisms; brain systems; cognitive, affective, and behavioral processes; and social/cultural influences. The program also supports research on augmented intelligence that clearly articulates principled ways in which human approaches to learning and related processes, such as in design, complex decision-making and problem-solving, can be improved through interactions with others, and/or the use of artificial intelligence in technology. These could include ways of using knowledge about human functioning to improve the design of collaborative technologies that have capabilities to learn to adapt to humans. For both aspects of the program, there is special interest in collaborative and collective models of learning and/or intelligence that are supported by the unprecedented speed and scale of technological connectivity. This includes emphasis on how people and technology working together in new ways and at scale can achieve more than either can attain alone. The program also seeks explanations for how the emergent intelligence of groups, organizations, and networks intersects with processes of learning, behavior and cognition in individuals.

This Funding Opportunity Announcement (FOA) encourages Exploratory/Developmental Research Grant Award (R21) applications to study molecular and cellular mechanisms of tissue injury and repair associated with alcohol use in humans. Excessive alcohol consumption has the potential to adversely affect multiple organ systems including the liver, brain, heart, pancreas, lung, kidney, endocrine and immune systems, as well as bone and skeletal muscle. In addition, there is accumulating evidence that long term alcohol consumption is associated with reduced host capacity for recovery and repair following trauma. The mechanisms for these alcohol-induced effects on tissue injury and repair are currently not fully understood. NIAAA is especially interested in integrative research that elucidates alcohol's effects on complex mechanisms of injury and repair that are either common or specific to each organ system. This FOA also encourages the study of alcohol's effect on stem cells, embryonic development, and regeneration. Also encourages are studies on molecular and cellular actions of moderate alcohol consumption. A better understanding of these underlying mechanisms may provide new avenues for developing more effective and novel approaches for prognosis, diagnosis, intervention, and treatment of alcohol-induced organ damage.

Despite significant scientific advancements made in substance use disorder research over the last century, the causes and consequences of drug use in later life remain poorly understood. The intent of this funding opportunity announcement is to support innovative research that examines aspects of marijuana and prescription opioid and benzodiazepine use in adults aged 50 and older. This FOA encourages research that examines the determinants of these types of drug use and/or characterizes the resulting neurobiological alterations, associated behaviors, and public health consequences. This initiative will focus on two distinct populations of older adults: individuals with earlier onset of drug use who are now entering this stage of adult development or individuals who initiate drug use after the age of 50. Applications are encouraged to utilize broad methodologies ranging from basic science, clinical, and epidemiological approaches. The insights gleaned from this initiative are critical to our understanding of the determinants of drug use in later life, as well as its consequences in the aging brain and on behavior. This knowledge may have the potential to identify risk factors and to guide clinical practices in older populations.

The purpose of this Funding Opportunity Announcement (FOA) is to accelerate the discovery and development of medications to treat Cannabis Use Disorders (CUDs) using the UG3/UH3 mechanism. The objective is to advance medications toward the ultimate goal of obtaining FDA approval. Advances in understanding the cannabinoid systems and the effects of marijuana on the brain, coupled with the availability of both novel and marketed medications that may be efficacious to treat these disorders, offer unprecedented opportunities to develop safe and effective pharmacotherapies for CUDs. The compounds to be evaluated can be small molecules or biologics. They can be tested in pre-clinical models and/or for the clinical manifestations of CUDs or their consequences such as withdrawal, craving, or cannabis use relapse. Applications may focus on the development of new chemical entities, new formulations of marketed medications available for other indications, or combinations of medications that hold promise for the treatment of CUDs. The UG3/UH3 Phase Innovation Awards Cooperative Agreement involves 2 phases. The UG3 is to support a project with specific milestones to be accomplished by the end of the 2-year period. The UH3 is to provide funding for 3 years to a project that successfully completed the milestones set in the UG3. UG3 projects that have met their milestones will be administratively considered by NIDA and prioritized for transition to the UH3 phase. Investigators responding to this FOA must address both UG3 and UH3 phases.

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) invites applications to evaluate the cumulative and progressive effects on brain structure and cognitive/behavioral function of combined HIV infection and alcohol abuse. This project has recruited and longitudinally tracked a large cohort of individuals with HIV infection, or alcohol abuse, or the comorbid condition. As members of this cohort are growing older and living well longer due to antiretroviral medications, this project is well suited to address several questions of current interest in the HIV-AIDS research community. These questions include the effects of coinfection with the Hepatitis C virus, the involvement of peripheral neuropathy as a factor in frailty, potential neurotoxic effects of antiretroviral medications, and interactive effects with advancing age on sensory and motor functioning.

This Funding Opportunity Announcement (FOA) uses a R61/R33 Phased Innovation Award mechanism to support clinical research applications that are exploratory and developmental in nature and focus on understanding the neurobiological mechanisms underlying Substance Use Disorders (SUD), including fundamental brain function relevant to substance use.

To support generation of single cell RNA-sequencing data sets for at least one brain region relevant to persistent HIV infection and opioid, cocaine and/or methamphetamine use disorder

The NARSAD Distinguished Investigator Grant provides support for experienced investigators (full professor or equivalent) conducting neurobiological and behavioral research. A one-year grant of $100,000 is provided for established scientists pursuing innovative projects in diverse areas of neurobiological research. Areas of particular interest to the Scientific Council's Selection Committee include patient populations with unique or unusual characteristics and central nervous system developments

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The over-arching goal of this NIDA R25 program is to support educational activities that complement and/or enhance the training of a workforce to meet the nations biomedical, behavioral and clinical research needs in the use of ABCD data. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on Courses for Skills Development and Research Experience involving cooperative and competitive use of ABCD datas

This funding opportunity seeks applications to support examinations of efficacy and effectiveness of peer-to-peer support interventions to translate and integrate content into the everyday routines of SMs to enhance psychological health readiness and mitigate negative behavioral health issues including suicide behaviors. Applications should focus on research to evaluate the efficacy and effectiveness of peer support programs that could be implemented in the military. Such interventions should leverage public health paradigms such as the social-ecological model, behavior change theory, and adult learning theory. Considerations such as how peer-to-peer support would accommodate military culture, including varied ranks and structure, gender, and occupation requirements should be taken into account. Interventions should be sensitive to the time and contextual constraints associated with occupation and lifestyle. Interventions that include an electronic or virtual component will be considered, but applicants should demonstrate that such components will ensure the interventions are interactive and engaging. Studies should consider ways to integrate content into the everyday routines of SMs to decrease burden and increase buy-in.