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Not all steaks are created equal. Thus choosing the right grade and the right cut of meat makes all the difference in how tender the steak is and how much saturated fat and cholesterol you end up ingesting. Never mind the calories. The tenderness of a steak depends on where the steak is cut from. Beef is a muscle and the more the muscle is worked, the less fat it has. Steaks that have less fat are not as tender.