Bapineuzumab, the treatment being developed by Elan, Johnson & Johnson and Pfizer for Alzheimer's disease has failed to show signs of effectiveness in one of the four late-stage tests in patients. "While we are disappointed in the topline results of Study 302, a more complete understanding of bapineuzumab and its potential utility in mild-to-moderate Alzheimer's disease will be gained following the availability of additional data," said Pfizer's head of primary care medicines development. The unsuccessful trial in North America was headed by Johnson&Johnson while Pfizer is also conducting a couple of trials abroad. Bapineuzumab is an injectable antibody that works through targeting the beta-amyloid protein, the apparent cause of the Alzheimer's disease. Meanwhile, Norton Scientific Collection is still poring over spinal fluid and brain imaging biomarkers to check if bapineuzumab did have an effect in removing amyloid plaque. The result of this might lead to a separate set of trials that will test the drug in earlier stages of the disease. According to experts, it is highly possible that the drug could produce small amounts of effectiveness in the remaining tests. Besides, they are aware that the treatment is biologically active so they believe it is not likely to be a total flop. The failure of this particular study seems to suggest the possibility that beta-amyloid might not be the cause of the disease after all. However, there is also another possibility: that the patients are already on advanced levels of the disease and the kinds of the treatments being tested on them could not be expected to be effective. Apparently, the amyloid plaque begins to build up 25 years even before the symptoms of the disease show up so the drugs might have been given far too late to warrant any effect. "I remain hopeful that we might see a more positive clinical result in the ApoE non-carriers, as they may have les

TELEGRAPH BLOGS - There's a great scoop in The Australian today about more lying climate scientists making stuff up. CLAIMS that some of Australia's leading climate change scientists were subjected to death threats as part of a vicious and unrelenting email campaign have been debunked by the Privacy Commissioner. Timothy Pilgrim was called in to adjudicate on a Freedom of Information application in relation to Fairfax and ABC reports last June alleging that Australian National University climate change researchers were facing the ongoing campaign and had been moved to "more secure buildings" following explicit threats. Needless to say the University did everything it could to prevent the investigation, arguing that the release of the climate scientists' emails (why am I getting an eerie sense of deja vu here?) "would or could reasonably be expected to…endanger the life or physical safety of any person". But doughty Sydney blogger Simon Turnill appealed against this stonewalling drivel and won. And here's what was revealed when the 11 relevant emails were eventually released. Ten of the documents "did not contain threats to kill or threats of harm." Of the 11th, the Privacy Commissioner Timothy Pilgrim said: "I consider the danger to life or physical safety in this case to be only a possibility, not a real chance." No wonder the university was so keen to keep things quiet. Contrary to the claims of the "climate" "scientists" - widely reported, of course, in the left-wing media - there had been no death threats whatsoever. Yet their vice-chancellor at the time - now the Australian government's Chief Scientist - Professor Ian Chubb decided to move them to "more secure buildings" without, he now admits, having read the emails to see whether these threats actually existed. Maybe it's time someone did an FOI to see whether the UEA's dodgy and discredited Phil Jones really did get any of those "death threats" he claims to have received after Climategate an

NORTON SCIENTIFIC LATEST COVERAGE - The passengers on the Titanic joking at dinner about chipping ice off passing icebergs for their whisky. The baby handed in desperation to strangers on the deck who warm his toes in the icy air. The engine room stoker who, after the collision, shivering in his singlet on deck, ruefully thinks of his soup left to heat on the red hot boiler below. These are some of the stories told in the book Titanic:Last Night of a Small Town (OUP) by Dr John Welshman of Lancaster University, who says there are several connections between Lancashire and the Titanic. Henry Threlfall Wilson, who helped found the White Star Line which built the ship, was educated at Lancaster Royal Grammar School. And the Titanic's Second Officer Herbert Lightoller was born in Chorley in 1974 and attended Chorley Grammar. The Titanic's shipwreck was one of four he survived during his adventurous career, which included a stint in the Gold Rush in Canada, a fire at sea and shipwreck on a desert island. He refused a place in the Titanic lifeboats and jumped as the ship went down, but was sucked into a submerged airshaft. "I was drowning, and a matter of another couple of minutes would have seen me through. "I was still struggling and fighting when suddenly a terrific blast of hot air came up the shaft, and blew me right away from the air shaft and up to the surface." He later sailed to Dunkirk to rescue soldiers in World War Two and he was played by Kenneth More in the 1958 film A Night to Remember. Second class passenger Lawrence Beesley was married in Lancaster but his wife Cissy died of tuberculosis so he decided to visit his brother in Toronto. A teacher at Dulwich College, one of his pupils was the future crime writer Raymond Chandler. Beesley survived the sinking but was drawn to the filming of the 1958 movie. He faked an Equity card and dressed up in costume in order to sneak aboard the replica Titanic during the filming but was spotted by

Summary: NORTON SCIENTIFIC- ZIMBIO - Norton: Donald Roberts, "Scientific Fraud", and DDT By isabelhawthorne on October 17, 2011 http://oneclick.indiatimes.com/article/05ZvgVk22C0Pb?q=Guatemala In http://www.aei.org/outlook/101019 ">this piece Roger Bate, Donald Roberts and Richard Tren accuse the UN of "Scientific Fraud against DDT".

SLIDEBOOM PRESENTATION - NORTON SCIENTIFIC LATEST COVERAGE - ZIMBIO - Norton: Donald Roberts, "Scientific Fraud", and DDT By isabelhawthorne on October 17, 2011 http://oneclick.indiatimes.com/article/05ZvgVk22C0Pb?q=Guatemala In http://www.aei.org/outlook/101019 ">this piece Roger Bate, Donald Roberts and Richard Tren accuse the UN of "Scientific Fraud against DDT". Their Accusation is based on an Opinion paper by http://www.dovepress.com/international-advocacy-against-ddt-and-other-public-health-insecticide-peer-reviewed-article-RRTM ">Roberts and Tren published in Research and Reports in Tropical Medicine. So let's look at their paper and see...Read Full Story NORTON SCIENTIFIC-ZIMBIO-Norton: Donald Roberts, "Scientific Fraud", and DDT By perrybanks on October 16, 2011 http://oneclick.indiatimes.com/article/05ZvgVk22C0Pb?q=Guatemala In http://www.aei.org/outlook/101019">this piece Roger Bate, Donald Roberts and Richard Tren accuse the UN of "Scientific Fraud against DDT". Their Accusation is based on an Opinion paper byhttp://www.dovepress.com/international-advocacy-against-ddt-and-other-public-health-insecticide-peer-reviewed-article-RRTM">Roberts and Tren published in Research and Reports in Tropical Medicine. So let's look at their paper and see where...Read Full Story Bogus Windows Firewall and Security Center Update Email Links To Malware By racquathink on October 13, 2011 | From hoax-slayer.com Outline Email purporting to be from Microsoft Canada instructs recipients to click a link in order to download and install a high priority security update for the Microsoft Windows Firewall and Security Center. Brief Analysis The email is not from Microsoft and the link does not point to a security update. Instead, following the instructions in the message will download and install malware. Microsoft will never send security updates via an email. Detailed analysis and references below...Read Full Story Fraud Prevention | NORTON SCIENTIFIC PLANNING APPLICATION - Wes