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Weiye Loh

Glowing trees could light up city streets - environment - 25 November 2010 - New Scientist - 0 views

  • If work by a team of undergraduates at the University of Cambridge pans out, bioluminescent trees could one day be giving our streets this dreamlike look. The students have taken the first step on this road by developing genetic tools that allow bioluminescence traits to be easily transferred into an organism.
  • Nature is full of glow-in-the-dark critters, but their shine is feeble - far too weak to read by, for example. To boost this light, the team, who were participating in the annual International Genetically Engineered Machines competition (iGEM), modified genetic material from fireflies and the luminescent marine bacterium Vibrio fischeri to boost the production and activity of light-yielding enzymes. They then made further modifications to create genetic components or "BioBricks" that can be inserted into a genome.
  • So are glowing trees coming soon to a street near you? It's unlikely, says Alexandra Daisy Ginsberg, a designer and artist who advised the Cambridge team. "We already have light bulbs," she says. "We're not going to spend our money and time engineering a replacement for something that works very well." However, she adds that "bio-light" has a distinctive allure. "There's something much more visceral about a living light. If you have to feed the light and look after it, then it becomes more precious."
Weiye Loh

TODAYonline | World | Off-the-shelf body parts? - 0 views

  • LONDON - Scientific advances including techniques allowing patients to grow new joints inside their own bodies will allow the elderly to remain active well beyond their 100th birthdays, researchers claim. British scientists are working on a system which should allow the elderly to buy body parts "off the shelf" and even regenerate their own damaged joints and hearts. Their ultimate aim is to fix up the body with customised replacement parts grown to order. They have already carried out human trials on heart valves which are still working four years after they were transplanted. At the University of Leeds, Britain's biggest bioengineering unit and the world leader in artificial joint replacement research is coordinating a project that aims to give people 50 active years after the age of 50."It is the rise of the bionic pensioner," said Professor Christina Doyle, whose company is working with the university to develop the new technologies. "The idea is when something wears out, your surgeon can buy a replacement off the shelf or, more accurately, in a bag."The university is spending £50 million ($114 million) over the next five years on the new project. The main thrust of the research centres on a method of tissue and medical engineering which the university is at the forefront of developing. Led by the immunologist Professor Eileen Ingham, they are pioneering a technique of stripping the living cells from donor human and animal parts, leaving just the collagen or elastin "scaffold" of the tissue. These "biological shells", which could be for knee, ankle or hip ligaments, as well as blood vessels and heart valves, are then transplanted into the patient whose own body then invades them replacing the removed cells with their own. The technique, which could be available within five years, effectively removes the need for anti-rejection drugs. It is similar to the recently developed system of using stem cells to regrow organs outside the body, but costs about a tenth of the price.
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