Skip to main content

Home/ Neuropsychology/ Group items tagged growth

Rss Feed Group items tagged

Tero Toivanen

Autism Blog - Autism: Is it all about bigger brains? « Left Brain/Right Brain - 0 views

  • in light of the increased cranial volumn and minicolumnar density in autism, more recent studies have begun targeting certain proteins and steroids called Growth Factors, which are in part intimately involved in neocortical expansion.
  • Basic Fibroblast Growth Factor (bFGF or FGF2) has particularly important implications in autism given its involvement in prolonging the period of cell division of the number of undifferentiated radial glial cells (cortical stem cells) which determine the total number of eventual minicolumns: the longer these radial glial divide, the greater the number of minicolumns, like that seen in autism.
  • It’s fascinating to think that while autism can undoubtedly provide for its share of handicap, these foundational elements may be “abnormal” only in the sense that they’re extremes of those things which make us most human.
  •  
    Basic Fibroblast Growth Factor (bFGF or FGF2) has particularly important implications in autism given its involvement in prolonging the period of cell division of the number of undifferentiated radial glial cells (cortical stem cells) which determine the total number of eventual minicolumns: the longer these radial glial divide, the greater the number of minicolumns, like that seen in autism.
Tero Toivanen

Learning keeps brain healthy: study - 0 views

  •  
    "The findings confirm a critical relationship between learning and brain growth and point to ways we can amplify that relationship through possible future treatments
Tero Toivanen

The five ages of the brain: Adolescence - life - 04 April 2009 - New Scientist - 0 views

  • Jay Giedd at the National Institute of Mental Health in Bethesda, Maryland, and his colleagues have followed the progress of nearly 400 children, scanning many of them every two years as they grew up. They found that adolescence brings waves of grey-matter pruning, with teens losing about 1 per cent of their grey matter every year until their early 20s (Nature Neuroscience, vol 2, p 861).
  • This cerebral pruning trims unused neural connections that were overproduced in the childhood growth spurt, starting with the more basic sensory and motor areas.
  • Among the last to mature is the dorsolateral prefrontal cortex at the very front of the frontal lobe. This area is involved in control of impulses, judgement and decision-making, which might explain some of the less-than-stellar decisions made by your average teen. This area also acts to control and process emotional information sent from the amygdala - the fight or flight centre of gut reactions - which may account for the mercurial tempers of adolescents.
  • ...5 more annotations...
  • These changes have both benefits and pitfalls. At this stage of life the brain is still childishly flexible, so we are still sponges for learning. On the other hand, the lack of impulse control may lead to risky behaviours such as drug and alcohol abuse, smoking and unprotected sex.
  • As grey matter is lost, though, the brain gains white matter
  • Substance abuse is particularly concerning, as brain imaging studies suggest that the motivation and reward circuitry in teen brains makes them almost hard-wired for addiction.
  • since drug abuse and stressful events - even a broken heart - have been linked to mood disorders later in life, this is the time when both are best avoided.
  • Making the most of this time is a matter of throwing all that teen energy into learning and new experiences - whether that means hitting the books, learning to express themselves through music or art, or exploring life by travelling the world.
  •  
    Jay Giedd at the National Institute of Mental Health in Bethesda, Maryland, and his colleagues have followed the progress of nearly 400 children, scanning many of them every two years as they grew up. They found that adolescence brings waves of grey-matter pruning, with teens losing about 1 per cent of their grey matter every year until their early 20s (Nature Neuroscience, vol 2, p 861).
Tero Toivanen

Does Vitamin D Improve Brain Function?: Scientific American - 0 views

  • And although vitamin D is well known for promoting bone health and regulating vital calcium levels—hence its addition to milk—it does more than that. Scientists have now linked this fat-soluble nutrient’s hormonelike activity to a number of functions throughout the body, including the workings of the brain.
  • We know there are receptors for vitamin D throughout the central nervous system and in the hippocampus
  • We also know vitamin D activates and deactivates enzymes in the brain and the cerebrospinal fluid that are involved in neurotransmitter synthesis and nerve growth.
  • ...5 more annotations...
  • In addition, animal and laboratory studies suggest vitamin D protects neurons and reduces inflammation.
  • The scientists found that the lower the subjects’ vitamin D levels, the more negatively impacted was their perform­ance on a battery of mental tests. Compared with people with optimum vitamin D levels, those in the lowest quartile were more than twice as likely to be cognitively impaired.
  • The data show that those people with lower vitamin D levels exhibited slower information-processing speed. This correlation was particularly strong among men older than 60 years.
  • Although we now know that low levels of vitamin D are associated with cognitive impairment, we do not know if high or optimum levels will lessen cognitive losses. It is also unclear if giving vitamin D to those who lack it will help them regain some of these high-level functions.
  • So how much is enough vitamin D? Experts say 1,000 to 2,000 IU daily—about the amount your body will synthesize from 15 to 30 minutes of sun exposure two to three times a week—is the ideal range for almost all healthy adults. Keep in mind, however, that skin color, where you live and how much skin you have exposed all affect how much vitamin D you can produce.
  •  
    And although vitamin D is well known for promoting bone health and regulating vital calcium levels-hence its addition to milk-it does more than that. Scientists have now linked this fat-soluble nutrient's hormonelike activity to a number of functions throughout the body, including the workings of the brain.
1 - 4 of 4
Showing 20 items per page