Steroid abuse has been associated with
cardiovascular diseases (CVD), including heart attacks and strokes, even in
athletes younger than 30. Steroids contribute to
the development of CVD, partly by changing the levels of lipoproteins that carry
cholesterol in the blood. Steroids, particularly
oral steroids, increase the level of low-density
lipoprotein (LDL) and decrease the level of high-density lipoprotein (HDL). High
LDL and low HDL levels increase the risk of atherosclerosis, a condition in
which fatty substances are deposited inside arteries and disrupt blood flow. If
blood is prevented from reaching the heart, the result can be a heart attack. If
blood is prevented from reaching the brain, the result can be a stroke.
Steroids also increase the risk that blood
clots will form in blood vessels, potentially disrupting blood flow and damaging
the heart muscle so that it does not pump blood effectively.