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Meningococcal meningitis - Prevention - 0 views

www.medmerits.com/...P6 EnglishII HSA MeningitisGoogleGroup Challenge1
shared by shaneep110 on 05 Sep 14 - No Cached
    • shaneep110
      shaneep110 on 05 Sep 14
       
      The first paragraph and maybe the second/third are the only ones of value.
  • Meningococcal disease risk can be decreased by approximately 90% in household contacts of a patient by administration of antibiotics known to eradicate meningococcal carriage
    • shaneep110
      shaneep110 on 05 Sep 14
       
      Meningococcal - Inflammation of the meninges due to infection with the bacterium Neisseria meningitidis.
  • hemoprophylaxis significantly decreased the risk of meningococcal disease for household contacts with a risk ratio of 0.11 for those receiving chemoprophylaxis
    • shaneep110
      shaneep110 on 05 Sep 14
       
      chemoprophylaxis - the use of drugs to prevent disease.
  • ...17 more annotations...
  • This is based on a meta-analysis of 4 retrospective studies and one small trial with 1249 cases of meningococcal disease and more than 4200 household contacts
  • In the United States, antimicrobial chemoprophylaxis is the primary means for prevention of meningococcal disease among close contacts of a patient with invasive meningococcal disease
    • shaneep110
      shaneep110 on 05 Sep 14
       
      antimicrobial - an agent that kills microorganisms or inhibits their growth. 
  • The number needed to treat to prevent a single secondary household case was 218
  • (Purcell et al 2004). T
  • herefore, chemoprophylaxis should be recommended for the index patient with meningococcal disease and all household contacts within 24 hours of diagnosis of the primary case.
  • There are no high quality experimental trials addressing control policies for meningococcal disease and no adequate studies of chemoprophylaxis in day care settings. Nevertheless, current management guidelines support chemoprophylaxis within 24 hours for all close contacts
  • Chemoprophylaxis administered more than 14 days after contact with an index case is probably of no value. Also, chemoprophylaxis does not protect against subsequent reacquisition of N meningitidis.
  • Close Contacts Warranting Chemoprophylaxis for Meningococcal Disease
    • shaneep110
      shaneep110 on 05 Sep 14
       
      New Title: ways of transmission 
  • Persons having contact with patient’s oral secretions during 7 days prior to disease onset
  • -- Kissing -- Sharing of toothbrushes -- Sharing of eating utensils -- Mouth-to-mouth resuscitation -- Unprotected contact during endotracheal intubation
    • shaneep110
      shaneep110 on 05 Sep 14
       
      Unprotected Sex
  • Persons at Low Risk for Whom Chemoprophylaxis is Not Recommended
    • shaneep110
      shaneep110 on 05 Sep 14
       
      New Title: Low Risk People
  • Casual contact (eg, at school or work) without direct exposure to patient’s oral secretions Indirect contact only (ie, only contact is with a high-risk contact and not a case) Health care worker without direct exposure to patient’s oral secretions
  • Rifampin, ceftriaxone, and ciprofloxacin
    • shaneep110
      shaneep110 on 05 Sep 14
       
      Rifampin - a reddish-brown antibiotic used chiefly to treat tuberculosis and leprosy. ceftriaxone - Treats infections caused by certain types of bacteria. This medicine is a cephalosporin antibiotic.  cephalosporin - any of a group of semisynthetic broad-spectrum antibiotics resembling penicillin. ciprofloxacin - This medicine is a quinolone antibiotic that treats infections and is given to people who have been exposed to anthrax. quinolone - any of a class of antibiotics used in treating a variety of mainly Gram-negative infections, and thought to be responsible for antibiotic resistance in some microbes. Gram-negative - a staining technique for the preliminary identification of bacteria, in which a violet dye is applied, followed by a decolorizing agent and then a red dye. The cell walls of certain bacteria
  • (Centers for Disease Control and Prevention 2000; 2001; Committee on Infectious Disease 2000).
  • azithromycin
    • shaneep110
      shaneep110 on 05 Sep 14
       
      azithromycin - Treats bacterial infections. This medicine is a macrolide antibiotic. macrolide - any of a class of antibiotics containing a lactone ring, of which the first and best known is erythromycin. lactone - an organic compound containing an ester group -OCO- as part of a ring. erythromycin - an antibiotic used in the treatment of infections caused byan antibiotic used in the treatment of infections caused by Gram-positive bacteria. It is similar in its effects to penicillin. Gram-positive - a staining technique for the preliminary identification of bacteria, in which a violet dye is applied, followed by a decolorizing agent and then a red dye. The cell walls of certain bacteria.
  • nasopharyngeal
    • shaneep110
      shaneep110 on 05 Sep 14
       
      nasopharyngeal - of or relating to or located near the nasopharynx nasopharynx - the upper part of the pharynx, connecting with the nasal cavity above the soft palate.
  • the drug of choice is rifampin, which is both effective and inexpensive. For young children rifampin can be administered with greater patient acceptance in a flavored syrup. Rifampin is not recommended for use in pregnant women. Rifampin may interfere with the efficacy of oral contraceptives, and some antiepileptic and anticoagulant medications. Rifampin may also stain the urine orange for a couple days and may stain soft contact lenses. Ciprofloxacin is also not recommended for use in pregnant women.
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Meningitis - Prevention.com - 1 views

www.prevention.com/...meningitis EnglishII HSA MeningitisGoogleGroup Challenge1
shared by shaneep110 on 05 Sep 14 - No Cached
  • Meningitis is an inflammation of coverings (meninges) of the brain and spinal cord.
  • Most often it is caused by a viral or bacterial infection.
  • systemic lupus erythematosus.
    • shaneep110
      shaneep110 on 05 Sep 14
       
      Systemic lupus erythematosus (SLE) is a disease that leads to long-term (chronic) inflammation.
  • ...37 more annotations...
  • Viral, or aseptic, meningitis is the most common type.
    • shaneep110
      shaneep110 on 05 Sep 14
       
      aspestic - free from contamination caused by harmful bacteria, viruses, or other microorganisms.
  • In general, viral meningitis is not directly contagious. Anyone can get viral meningitis, but it occurs most often in children. Many different viruses can cause meningitis
  • an enterovirus tends to be the usual culprit.
    • shaneep110
      shaneep110 on 05 Sep 14
       
      Meaning of enterovirus - any of a group of RNA viruses that typically occur in the gastrointestinal tract, sometimes spreading to the central nervous system or other parts of the body. gastrointestinal - of or relating to the stomach and the intestines.
  • In the past, the three most common types of bacterial meningitis were caused by Neisseria meningitidis, Haemophilus influenza and Streptococcus pneumoniae.
    • shaneep110
      shaneep110 on 05 Sep 14
       
      Neisseria meningitidis, often referred to as meningococcus, is a bacterium that can cause meningitis and other forms of meningococcal disease such as meningococcemia, a life-threatening sepsis. Haemophilus influenzae is a Gram-negative, coccobacillary, facultatively anaerobic bacterium belonging to the Pasteurellaceae family. H. influenzae was first described in 1892 by Richard Pfeiffer during an influenza pandemic. Streptococcus pneumoniae, or pneumococcus, is a Gram-positive, alpha-hemolytic, aerotolerant, aerobic member of the genus Streptococcus.
  • Viral meningitis due to enterovirus peaks in mid-summer through early autumn. But it can occur any time of the year.
  • Bacterial meningitis
  • is a very serious and potentially fatal infection.
  • It can strike very healthy people, but infants and older people are more susceptible.
  • Except for the rare case of herpes meningitis, viral meningitis will resolve on its own after 7 to 10 days.
  • Now that we have very effective vaccines to help prevent all three types, bacterial meningitis in otherwise healthy children and adults occurs less often.
  • Besides infants and the elderly, people with chronic diseases and/or impaired immune systems have the greatest risk of meningitis caused by bacteria and fungi.
  • Symptoms
    • shaneep110
      shaneep110 on 05 Sep 14
       
      These three are common side-effects, so it may not be noticed at first.
  • The symptoms of meningitis vary, but often include:
    • shaneep110
      shaneep110 on 05 Sep 14
       
      All are common except sensitivity to light, so meningitis is hard to figure out when its happening.
  • Other symptoms may include:
  • Symptoms may be milder in cases of viral meningitis, while in cases of bacterial meningitis, symptoms may come on quite suddenly. In very young children, symptoms may be particularly hard to detect.
  • The fluid is removed from the spinal cord with a needle in a procedure known as a spinal tap or lumbar puncture.
    • shaneep110
      shaneep110 on 05 Sep 14
       
      Lumbar- back
  • Diagnosis
  • Meningitis is diagnosed by testing some of the fluid that surrounds the spinal cord for disease-causing bacteria or infection-fighting cells.
  • Babies with meningitis may be less active, vomit, refuse to eat or be irritable. A person in later stages of bacterial meningitis may have seizures and lose consciousness (pass out).
  • Expected Duration
  • Some people carry the germs in their nose and throat and can pass them on to other people, even though these "carriers" are not sick.
  • Viral meningitis tends to get better on its own in seven to 10 days. In contrast, if bacterial meningitis is not diagnosed and treated early, it can cause permanent disability or death.
  • Prevention
  • he bacteria and viruses that cause meningitis are found in bodily fluids, such as saliva and mucus, and are spread by direct contact.
  • The length of time that medication is needed for bacterial meningitis depends on the person's age, response to the medication and other factors.
  • If you are in close contact with someone who has been diagnosed with bacterial meningitis, you may be given antibiotics to prevent you from getting the disease.
  • Vaccination against Streptococcus pneumoniae (pneumonia shot), Haemophilus influenzae and Neisseria meningitidis is the best way to prevent bacterial meningitis.
    • shaneep110
      shaneep110 on 05 Sep 14
       
      Definitions above
  • There is no vaccine to prevent the common types of viral meningitis.
    • shaneep110
      shaneep110 on 05 Sep 14
       
      Look up research on what's being done about this, perhaps.
  • Bacterial meningitis is a medical emergency. It requires high dose intravenous antibiotics in a hospital setting. Depending upon the patient and suspected type of bacterial meningitis, intravenous dexamethasone, a corticosteroid, may be given at the time of diagnosis
    • shaneep110
      shaneep110 on 05 Sep 14
       
      Intravenous - IV Dexamethasone is a potent synthetic member of the glucocorticoid class of steroid drugs that has anti-inflammatory and immunosuppressant effects. Corticosteroid - any of a group of steroid hormones produced in the adrenal cortex or made synthetically. There are two kinds: glucocorticoids and mineralocorticoids. They have various metabolic functions and some are used to treat inflammation.
  • Viral meningitis is treated much like the flu, with rest and plenty of fluids, and you should recover in a week to 10 days.
  • Treatment
  • If you or your child is exhibiting symptoms of meningitis, contact your doctor immediately.
  • For people with viral meningitis, the outlook is excellent.
  • The prognosis for bacterial meningitis depends on the person's age, which bacterium is causing the disease, and how early the disease was diagnosed.
  • Up to 10% of people with this disease will die, and a larger percentage of survivors have long-term consequences, such as hearing loss or neurological problems.
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