How big a role does randomness play in our lives? Do we live in a world of magic and meaning or … is it all just chance and happenstance? To tackle this question, we look at the role chance and randomness play in sports, lottery tickets, and even the cells in our own body. Along the way, we talk to a woman suddenly consumed by a frenzied gambling addiction, two friends whose meeting seems purely providential, and some very noisy bacteria.